Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr3 57561286 . G A CCDS2884.1:NM_001660.3:c.445Cgt>Tgt_NP_001651.1:p.149R>C Homo sapiens ADP ribosylation factor 4 (ARF4), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1z6x 1 P18085 100.0 5e-133 X-RAY
 2005-04-12 ARG A:149 A:149 179.0 0.796 -91.2 -58.8 179.0 0.796 0.0 HOH
 6.130
 O
 O
ARG B:149 B:149 169.0 0.751 -116.8 164.0 NA NA NA
2b6h 1 P84085 90.8 5e-119 X-RAY
 2005-10-11 ARG A:161 A:149 225.0 1.0 S -117.3 139.4 225.0 1.0 0.0 UNX
HOH
 8.189
4.677
 CA
O
 UNK
O
3aq4 1 P36397 80.56 1e-109 X-RAY
 2011-01-26 ARG A:152 A:149 245.0 1.0 S -121.3 -28.8 245.0 1.0 0.0 HOH
 2.464
 O
 O
ARG B:152 B:149 228.0 1.0 T -78.2 -17.5 NA NA NA
1r8q 1 P84080 81.92 2e-108 X-RAY
 2004-01-20 ARG A:149 A:149 178.0 0.791 -131.2 147.6 178.0 0.791 0.0 HOH
 2.572
 O
 O
ARG C:149 B:149 183.0 0.813 -121.0 159.2 NA NA NA
1rrf 1 P84079 81.92 2e-108 X-RAY
 1996-06-20 ARG A:149 A:149 104.0 NA S -104.4 60.8 104.0 NA NA
1rrg 1 P84079 81.92 2e-108 X-RAY
 1996-06-20 ARG A:149 A:149 201.0 0.893 -93.2 90.3 201.0 0.893 0.0 HOH
 4.389
 CA
 O
ARG B:149 B:149 214.0 0.951 S -84.0 3.3 214.0 0.951 0.0 HOH
 3.621
 CA
 O
1hur 1 P84077 81.82 2e-107 X-RAY
 1995-07-10 ARG A:148 A:149 186.0 0.827 -91.8 142.9 186.0 0.827 0.0 HOH
 3.898
 NE
 O
ARG B:148 B:149 195.0 0.867 -92.1 158.1 195.0 0.867 0.0 HOH
 8.502
 NH1
 O
3o47 1 Q8N6T3,P84077 84.94 5e-103 X-RAY
 2010-08-11 ARG A:297 A:279 167.0 0.742 -120.3 167.7 167.0 0.742 0.0
ARG B:297 B:279 72.0 NA -117.4 141.7 NA NA NA
6ii6 2 P61204 82.53 2e-102 X-RAY
 2019-08-07 ARG C:137 C:149 177.0 0.787 T -93.8 140.0 177.0 0.787 0.0 HOH
 2.474
 NH1
 O
ARG D:137 D:149 202.0 0.898 -109.6 177.4 NA NA NA
7mge 4 P84077 84.47 7e-102 EM
 2021-06-23 ARG D:135 E:149 175.0 0.778 S -132.6 136.4 175.0 0.778 0.0
7dn8 2 P84077 82.93 1e-101 X-RAY
 2021-12-15 ARG B:137 D:149 175.0 0.778 -133.5 147.1 175.0 0.778 0.0 HOH
 2.828
 N
 O
ARG D:137 B:149 173.0 0.769 -133.4 147.2 NA NA NA
ARG F:137 F:149 174.0 0.773 -134.0 147.3 NA NA NA
ARG H:137 H:149 173.0 0.769 -133.3 147.3 NA NA NA
1r8s 1 P84080 85.0 1e-101 X-RAY
 2004-01-20 ARG A:132 A:149 215.0 0.956 S -103.6 -46.0 215.0 0.956 0.0 FMT
HOH
 3.508
4.262
 N
N
 O1
O
1re0 1 P32889 85.0 1e-101 X-RAY
 2003-12-16 ARG A:132 A:149 222.0 0.987 S -80.4 -29.7 222.0 0.987 0.0 CIT
HOH
 2.498
4.496
 N
C
 O7
O
1s9d 1 P84080 85.0 1e-101 X-RAY
 2004-02-10 ARG A:132 A:149 197.0 0.876 T -71.4 -29.7 197.0 0.876 0.0 HOH
 3.625
 N
 O
1u81 1 P84077 85.0 1e-101 NMR
 2004-10-05 ARG A:132 A:149 105.0 0.467 -121.3 -169.3 105.0 0.467 0.0
4c0a 2 P84080 85.0 1e-101 X-RAY
 2013-09-25 ARG C:132 C:149 226.0 1.0 -134.3 48.7 NA NA NA
ARG D:132 D:149 209.0 0.929 S -124.0 42.7 NA NA NA
ARG G:132 G:149 224.0 0.996 -107.5 -74.2 224.0 0.996 0.0
ARG H:132 H:149 201.0 0.893 -97.3 -93.9 NA NA NA
6fae 2 P84077 83.95 4e-101 X-RAY
 2018-01-17 ARG B:181 B:149 105.0 NA T -75.2 -61.0 105.0 NA NA HOH
 9.723
 N
 O
4hmy 5 P84077 83.85 2e-100 X-RAY
 2013-03-06 ARG E:140 C:149 214.0 0.951 -87.4 153.2 214.0 0.951 0.0
6cri 3 P84077 83.85 2e-100 EM
 2018-08-01 ARG C:133 C:149 181.0 0.804 T -69.9 145.7 181.0 0.804 0.0
ARG E:133 H:149 172.0 0.764 S -127.2 136.6 163.0 0.724 0.04 U:P84077:0.04
ARG K:133 K:149 182.0 0.809 T -72.9 145.1 182.0 0.809 0.0
ARG M:133 U:149 166.0 0.738 S -138.3 136.2 72.0 0.32 0.418 E:P84077:0.418
ARG S:133 L:149 188.0 0.836 T -74.8 145.9 188.0 0.836 0.0
ARG U:133 V:149 173.0 0.769 S -135.7 132.7 63.0 0.28 0.489 M:P84077:0.489
7dn9 2 P84077 83.85 2e-100 X-RAY
 2021-12-15 ARG B:133 B:149 181.0 0.804 -129.3 143.9 181.0 0.804 0.0
ARG D:133 D:149 177.0 0.787 -129.3 143.0 NA NA NA
ARG F:133 F:149 177.0 0.787 -129.0 143.4 NA NA NA
ARG H:133 H:149 177.0 0.787 -128.8 143.3 NA NA NA
1j2j 1 Q8BSL7 84.38 3e-100 X-RAY
 2003-05-06 ARG A:134 A:149 209.0 0.929 -109.6 151.2 209.0 0.929 0.0 HOH
 3.009
 O
 O
1o3y 1 P84078 84.38 3e-100 X-RAY
 2003-05-20 ARG A:134 A:149 208.0 0.924 -115.3 142.5 208.0 0.924 0.0 HOH
 2.584
 O
 O
ARG B:134 B:149 167.0 0.742 -130.0 157.7 NA NA NA
2j59 1 P84078 84.38 3e-100 X-RAY
 2007-02-20 ARG A:134 A:149 185.0 0.822 -92.1 -8.0 185.0 0.822 0.0 HOH
 3.506
 N
 O
ARG B:134 B:149 189.0 0.84 T -81.0 -21.4 NA NA NA
ARG C:134 C:149 202.0 0.898 -120.3 158.0 NA NA NA
ARG D:134 D:149 186.0 0.827 -98.5 -37.8 NA NA NA
ARG E:134 E:149 204.0 0.907 -121.6 153.6 NA NA NA
ARG F:134 F:149 172.0 0.764 -131.7 156.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p18085-f1 1 P18085 100.0 2e-133 ARG A:149 A:149 226.0 1.0 T -75.0 -29.9
af-p84085-f1 1 P84085 90.0 2e-123 ARG A:149 A:149 239.0 1.0 T -70.7 -27.6
af-p84077-f1 1 P84077 81.92 1e-108 ARG A:149 A:149 215.0 0.956 T -64.4 -23.4