Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 102001781 . T A CCDS34037.1:NM_000944.4:c.863tAc>tTc_NP_000935.1:p.288Y>F Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1aui 1 Q08209 100.0 0.0 X-RAY
 1997-12-03 TYR A:288 A:288 72.0 0.313 E -159.9 172.9 72.0 0.313 0.0 HOH
 3.803
 CE2
 O
4orb 1 P63328 97.7 0.0 X-RAY
 2015-05-20 TYR A:288 A:288 73.0 0.317 E -156.6 161.3 73.0 0.317 0.0
4il1 1 P62161,P63100,P63329 97.76 0.0 X-RAY
 2013-10-02 TYR A:621 A:621 74.0 0.322 E -154.4 -174.2 74.0 0.322 0.0 HOH
 7.960
 CE1
 O
TYR B:621 B:621 71.0 0.309 E -154.1 -173.6 NA NA NA
TYR C:621 C:621 71.0 0.309 E -152.4 -171.9 NA NA NA
TYR D:621 D:621 72.0 0.313 E -154.8 -171.5 NA NA NA
4or9 1 P16298 85.63 0.0 X-RAY
 2015-05-20 TYR A:317 A:297 76.0 0.33 E -158.9 167.1 76.0 0.33 0.0 HOH
 3.013
 O
 O
4orc 1 P16298 85.63 0.0 X-RAY
 2015-05-20 TYR A:317 A:297 79.0 0.343 E -152.9 170.8 79.0 0.343 0.0 HOH
 9.547
 CE1
 O
4ora 1 P16298 85.23 0.0 X-RAY
 2015-05-20 TYR A:317 A:297 76.0 0.33 E -157.2 161.7 76.0 0.33 0.0 HOH
 3.782
 CE2
 O
2p6b 2 Q08209 100.0 0.0 X-RAY
 2007-06-05 TYR B:291 A:288 66.0 0.287 E -165.3 166.9 38.0 0.165 0.122 D:Q08209:0.061
A:None:0.1
 HOH
 3.179
 O
 O
TYR D:291 C:288 69.0 0.3 E -170.2 170.0 34.0 0.148 0.152 B:Q08209:0.022
A:None:0.148
 HOH
 4.406
 CE2
 O
1tco 1 P48452 99.73 0.0 X-RAY
 1997-02-12 TYR A:271 A:288 76.0 0.33 E -168.5 169.0 76.0 0.33 0.0 HOH
 2.845
 OH
 O
1mf8 1 Q08209 100.0 0.0 X-RAY
 2002-10-16 TYR A:269 A:288 70.0 0.304 E 173.7 169.2 70.0 0.304 0.0
1m63 1 Q08209 100.0 0.0 X-RAY
 2002-09-25 TYR A:288 A:288 70.0 0.304 -158.9 171.0 70.0 0.304 0.0
TYR E:288 E:288 71.0 0.309 E -167.0 177.2 71.0 0.309 0.0
5sve 1 Q08209 100.0 0.0 X-RAY
 2017-01-11 TYR A:288 A:288 79.0 0.343 E -154.3 167.9 79.0 0.343 0.0 HOH
 7.573
 O
 O
4f0z 1 Q08209 100.0 0.0 X-RAY
 2013-03-06 TYR A:290 A:288 73.0 0.317 E -161.9 162.6 50.0 0.217 0.1 C:O36972:0.1
 GOL
HOH
 8.668
2.076
 HE1
HH
 HO3
O
6nuc 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 TYR A:290 A:288 75.0 0.326 E -159.3 160.1 53.0 0.23 0.096 C:P19634:0.096
 HOH
 2.051
 HH
 O
6nuf 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 TYR A:290 A:288 78.0 0.339 E -162.2 160.7 53.0 0.23 0.109 C:P19634:0.109
 HOH
 2.207
 HH
 O
6nuu 1 Q08209 99.46 0.0 X-RAY
 2019-07-03 TYR A:290 A:288 75.0 0.326 E -161.7 164.2 47.0 0.204 0.122 C:P19634:0.122
 HOH
 2.359
 HH
 O
3ll8 2 Q08209 100.0 0.0 X-RAY
 2011-01-12 TYR B:275 A:288 65.0 0.283 E -158.1 165.3 42.0 0.183 0.1 A:P24588:0.1
 HOH
 3.632
 O
 O
TYR D:275 C:288 69.0 0.3 E -160.0 161.6 NA NA NA
5c1v 1 Q08209 99.42 0.0 X-RAY
 2016-02-03 TYR A:287 A:288 71.0 0.309 E -160.5 177.3 71.0 0.309 0.0
TYR B:287 NA:NA DO NA DO DO DO NA NA NA
6uuq 1 Q08209 100.0 0.0 X-RAY
 2020-09-09 TYR A:265 A:288 85.0 0.37 E -160.4 163.8 50.0 0.217 0.153 B:P53805:0.152
 HOH
 2.841
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q08209-f1 1 Q08209 100.0 0.0 TYR A:288 A:288 74.0 0.322 E -153.2 160.2
af-p16298-f1 1 P16298 85.63 0.0 TYR A:297 A:297 78.0 0.339 E -155.3 162.5
af-p48454-f1 1 P48454 81.84 0.0 TYR A:284 A:284 75.0 0.326 E -152.8 161.4