Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 102030143 . C A CCDS34037.1:NM_000944.4:c.352Gac>Tac_NP_000935.1:p.118D>Y Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1aui 1 Q08209 100.0 0.0 X-RAY
 1997-12-03 ASP A:118 A:118 0.0 0.0 64.3 62.1 0.0 0.0 0.0 ZN
FE
HOH
 2.604
2.263
3.747
 OD2
OD2
OD2
 ZN
FE
O
4orb 1 P63328 97.7 0.0 X-RAY
 2015-05-20 ASP A:118 A:118 2.0 0.013 64.9 64.3 2.0 0.013 0.0 ZN
FE
HOH
 2.470
3.064
4.624
 OD2
OD2
OD2
 ZN
FE
O
4il1 1 P62161,P63100,P63329 97.76 0.0 X-RAY
 2013-10-02 ASP A:451 A:451 2.0 0.013 52.0 70.2 2.0 0.013 0.0 HOH
 3.027
 OD2
 O
ASP B:451 B:451 1.0 0.007 49.0 70.9 NA NA NA
ASP C:451 C:451 2.0 0.013 48.4 72.4 NA NA NA
ASP D:451 D:451 2.0 0.013 -89.0 107.6 NA NA NA
4or9 1 P16298 85.63 0.0 X-RAY
 2015-05-20 ASP A:147 A:127 2.0 0.013 55.6 68.2 2.0 0.013 0.0 FE
ZN
HOH
 2.479
2.581
4.253
 OD2
OD2
N
 FE
ZN
O
4orc 1 P16298 85.63 0.0 X-RAY
 2015-05-20 ASP A:147 A:127 2.0 0.013 70.3 53.7 2.0 0.013 0.0 ZN
FE
PO4
HOH
 2.556
2.637
3.536
4.932
 OD2
OD2
OD2
N
 ZN
FE
O1
O
4ora 1 P16298 85.23 0.0 X-RAY
 2015-05-20 ASP A:147 A:127 1.0 0.007 59.6 59.9 1.0 0.007 0.0 ZN
FE
HOH
 2.916
3.685
4.151
 OD2
OD2
N
 ZN
FE
O
2p6b 2 Q08209 100.0 0.0 X-RAY
 2007-06-05 ASP B:121 A:118 3.0 0.02 58.6 59.4 3.0 0.02 0.0 ZN
FE
PO4
HOH
 2.396
2.228
3.104
4.419
 OD2
OD2
OD2
N
 ZN
FE
O1
O
ASP D:121 C:118 4.0 0.027 55.9 58.4 4.0 0.027 0.0 ZN
FE
PO4
HOH
 2.605
2.196
3.063
4.279
 OD2
OD2
OD2
CB
 ZN
FE
O1
O
1tco 1 P48452 99.73 0.0 X-RAY
 1997-02-12 ASP A:101 A:118 3.0 0.02 48.9 66.2 3.0 0.02 0.0 ZN
FE
PO4
HOH
 2.387
2.321
3.174
4.207
 OD2
OD2
OD2
N
 ZN
FE
O2
O
1mf8 1 Q08209 100.0 0.0 X-RAY
 2002-10-16 ASP A:99 A:118 2.0 0.013 71.4 68.0 2.0 0.013 0.0 PO4
 7.036
 OD2
 O3
1m63 1 Q08209 100.0 0.0 X-RAY
 2002-09-25 ASP A:118 A:118 1.0 0.007 54.7 71.5 1.0 0.007 0.0 ZN
FE
 2.257
2.275
 OD2
OD2
 ZN
FE
ASP E:118 E:118 1.0 0.007 45.1 71.2 1.0 0.007 0.0 ZN
FE
 2.255
2.289
 OD2
OD2
 ZN
FE
5sve 1 Q08209 100.0 0.0 X-RAY
 2017-01-11 ASP A:118 A:118 2.0 0.013 57.1 63.4 2.0 0.013 0.0 FE
ZN
HOH
 2.207
2.447
2.631
 OD2
OD2
OD2
 FE
ZN
O
4f0z 1 Q08209 100.0 0.0 X-RAY
 2013-03-06 ASP A:120 A:118 2.0 0.013 56.3 62.6 2.0 0.013 0.0 GOL
HOH
 3.568
2.491
 OD2
OD2
 HO1
O
6nuc 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 ASP A:120 A:118 3.0 0.02 53.9 62.0 3.0 0.02 0.0 FE
ZN
PO4
HOH
 2.183
2.252
3.173
2.585
 OD2
OD2
OD2
OD2
 FE
ZN
O4
O
6nuf 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 ASP A:120 A:118 4.0 0.027 55.2 62.0 4.0 0.027 0.0 FE
ZN
PO4
HOH
 2.105
2.216
3.026
2.510
 OD2
OD2
OD2
OD2
 FE
ZN
O4
O
6nuu 1 Q08209 99.46 0.0 X-RAY
 2019-07-03 ASP A:120 A:118 2.0 0.013 49.4 65.2 2.0 0.013 0.0 FE
ZN
PO4
HOH
 2.092
2.325
3.208
2.777
 OD2
OD2
OD2
OD2
 FE
ZN
O4
O
3ll8 2 Q08209 100.0 0.0 X-RAY
 2011-01-12 ASP B:105 A:118 3.0 0.02 57.8 53.8 3.0 0.02 0.0 PO4
ZN
FE
HOH
 3.235
2.265
2.294
4.230
 OD2
OD2
OD2
N
 O1
ZN
FE
O
ASP D:105 C:118 3.0 0.02 52.5 54.8 NA NA NA
5c1v 1 Q08209 99.42 0.0 X-RAY
 2016-02-03 ASP A:117 A:118 2.0 0.013 55.4 64.9 2.0 0.013 0.0 FE
ZN
PO4
 2.563
2.118
2.950
 OD2
OD2
OD2
 FE
ZN
O4
ASP B:117 B:118 2.0 0.013 54.1 65.4 NA NA NA
6uuq 1 Q08209 100.0 0.0 X-RAY
 2020-09-09 ASP A:95 A:118 3.0 0.02 56.3 61.6 3.0 0.02 0.0 PO4
PO4
ZN
FE
HOH
 3.072
4.312
2.151
2.263
2.685
 OD2
OD2
OD2
OD2
OD2
 O1
O2
ZN
FE
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q08209-f1 1 Q08209 100.0 0.0 ASP A:118 A:118 2.0 0.013 54.4 64.9
af-p16298-f1 1 P16298 85.63 0.0 ASP A:127 A:127 1.0 0.007 54.6 61.6
af-p48454-f1 1 P48454 81.84 0.0 ASP A:114 A:114 2.0 0.013 54.0 63.7