Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 103505915 . G A CCDS3657.1:NM_003998.3:c.1004cGg>cAg_NP_003989.2:p.335R>Q Homo sapiens nuclear factor kappa B subunit 1 (NFKB1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1svc 2 P19838 99.73 0.0 X-RAY
 1996-06-10 ARG B:334 P:335 46.0 0.204 E -144.0 133.9 46.0 0.204 0.0 HOH
 3.753
 CD
 O
2v2t 2 P25799 98.16 0.0 X-RAY
 2007-07-03 ARG B:295 B:332 48.0 0.213 E -150.0 144.3 48.0 0.213 0.0 HOH
 8.594
 NE
 O
1nfk 2 P25799 98.15 0.0 X-RAY
 1996-12-23 ARG C:294 A:332 45.0 0.2 E -147.3 138.9 45.0 0.2 0.0 HOH
 1.677
 HH21
 O
ARG D:294 B:332 33.0 0.147 E -159.5 136.2 33.0 0.147 0.0 HOH
 2.826
 HH12
 O
1ooa 2 P25799 98.15 0.0 X-RAY
 2003-07-22 ARG C:295 A:332 39.0 0.173 E -148.0 133.8 39.0 0.173 0.0 HOH
 3.098
 NH1
 O
ARG D:295 B:332 48.0 0.213 E -147.9 136.9 NA NA NA
2o61 4 P19838 100.0 0.0 X-RAY
 2007-07-24 ARG D:296 B:332 40.0 0.178 E -148.3 134.4 40.0 0.178 0.0
1le5 4 P25799 98.08 0.0 X-RAY
 2003-04-15 ARG F:295 B:332 38.0 0.169 E -139.4 145.9 38.0 0.169 0.0 HOH
 3.191
 NH2
 O
ARG H:295 F:332 21.0 0.093 E -141.1 147.9 NA NA NA
1le9 4 P25799 98.08 0.0 X-RAY
 2003-04-15 ARG F:295 B:332 43.0 0.191 E -139.9 138.2 43.0 0.191 0.0
ARG H:295 F:332 31.0 0.138 E -136.3 137.4 NA NA NA
1lei 4 P25799 98.08 0.0 X-RAY
 2003-04-15 ARG D:295 B:332 46.0 0.204 E -136.0 126.7 46.0 0.204 0.0 HOH
 8.828
 O
 O
2i9t 4 P25799 98.08 0.0 X-RAY
 2007-02-06 ARG D:295 B:632 49.0 0.218 E -148.3 137.6 49.0 0.218 0.0
1vkx 4 P25799 98.08 0.0 X-RAY
 1998-12-09 ARG D:294 B:632 26.0 0.116 -155.1 128.2 26.0 0.116 0.0
3gut 2 P19838 98.08 0.0 X-RAY
 2009-09-08 ARG B:294 B:632 47.0 0.209 E -149.2 123.7 47.0 0.209 0.0
ARG D:294 D:632 39.0 0.173 E -170.3 120.8 39.0 0.173 0.0
ARG F:294 F:632 43.0 0.191 E -149.6 122.8 NA NA NA
ARG H:294 H:632 44.0 0.196 B -175.5 115.5 NA NA NA
1ikn 2 P25799 99.16 5e-80 X-RAY
 1999-04-12 ARG B:88 C:332 40.0 0.178 E -156.8 129.0 40.0 0.178 0.0 HOH
 2.805
 CD
 O
3jv4 2 P25799 99.13 4e-77 X-RAY
 2010-11-24 ARG B:88 B:332 51.0 0.227 E -152.1 142.4 51.0 0.227 0.0
ARG D:88 D:332 45.0 0.2 E -140.9 130.9 NA NA NA
ARG F:88 F:332 37.0 0.164 E -158.8 143.8 NA NA NA
1nfi 2 P19838 100.0 4e-72 X-RAY
 1998-11-18 ARG B:87 B:335 43.0 0.191 E -141.1 124.3 43.0 0.191 0.0 HOH
 2.906
 NH2
 O
ARG D:87 D:335 43.0 0.191 E -141.2 124.4 NA NA NA
1u36 1 P25799 97.17 3e-70 X-RAY
 2004-08-17 ARG A:88 A:332 39.0 0.173 E -144.8 131.9 39.0 0.173 0.0 HOH
 2.904
 NH1
 O
1u41 1 P25799 98.11 3e-70 X-RAY
 2004-08-17 ARG A:88 A:332 62.0 0.276 B -151.9 143.4 62.0 0.276 0.0 HOH
 1.864
 NH2
 O
ARG B:88 B:332 47.0 0.209 E -151.5 129.3 47.0 0.209 0.0 HOH
 3.021
 NH2
 O
ARG C:88 C:332 52.0 0.231 E -160.0 138.8 NA NA NA
ARG D:88 D:332 53.0 0.236 E -138.4 134.3 NA NA NA
1bfs 1 P25799 99.06 2e-69 X-RAY
 1998-01-28 ARG A:88 A:332 41.0 0.182 E -149.9 125.4 41.0 0.182 0.0 HOH
 1.909
 HE
 H1
1u3y 1 P25799 97.17 2e-69 X-RAY
 2004-08-17 ARG A:88 A:332 40.0 0.178 E -144.4 130.5 40.0 0.178 0.0 HOH
 2.811
 NH1
 O
1u3j 1 P25799 98.11 2e-68 X-RAY
 2004-08-17 ARG A:88 A:332 39.0 0.173 E -143.5 132.7 39.0 0.173 0.0 HOH
 2.865
 NH2
 O
1u42 1 P25799 97.17 4e-68 X-RAY
 2004-08-17 ARG A:88 A:332 164.0 0.729 B -147.7 130.2 49.0 0.218 0.511 A:P25799:0.511
 HOH
 3.102
 NH2
 O
1u3z 1 P25799 97.17 7e-68 X-RAY
 2004-08-17 ARG A:88 A:332 40.0 0.178 E -141.2 133.1 40.0 0.178 0.0 HOH
 2.853
 NH1
 O
7rg4 2 P19838 100.0 7e-21 X-RAY
 2021-08-25 ARG B:4 NA:NA DO NA DO DO DO NA NA NA
7rg5 2 P19838-3 100.0 7e-21 X-RAY
 2021-08-25 ARG B:4 NA:NA DO NA DO DO DO NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19838-f1 1 P19838 99.9 0.0 ARG A:334 A:334 43.0 0.191 E -133.0 134.3