Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 123372914 . A C CCDS3726.1:NM_000586.3:c.455cTg>cGg_NP_000577.2:p.152L>R Homo sapiens interleukin 2 (IL2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ye3 3 P60568 100.0 1e-95 X-RAY
 2020-12-30 LEU C:133 C:127 49.0 0.288 T -73.3 -8.0 49.0 0.288 0.0
LEU F:133 F:127 64.0 0.376 H -75.0 -49.1 NA NA NA
LEU I:133 I:127 117.0 0.688 -81.0 360.0 NA NA NA
1m47 1 P60568 100.0 2e-95 X-RAY
 2002-07-31 LEU A:132 A:132 36.0 0.212 T -112.3 -3.5 36.0 0.212 0.0 HOH
 7.083
 CD2
 O
1m48 1 P60568 100.0 2e-95 X-RAY
 2002-07-31 LEU A:132 A:132 81.0 0.476 -133.7 360.0 81.0 0.476 0.0 HOH
 2.721
 O
 O
LEU B:132 B:132 49.0 0.288 T -108.5 61.8 NA NA NA
1m49 1 P60568 100.0 2e-95 X-RAY
 2002-07-31 LEU A:132 A:132 92.0 0.541 -86.9 360.0 92.0 0.541 0.0 HOH
 7.232
 CD2
 O
LEU B:132 B:132 41.0 0.241 T -108.2 40.3 NA NA NA
1m4c 1 P60568 100.0 2e-95 X-RAY
 2002-07-31 LEU A:132 NA:NA DO NA DO DO DO NA NA NA
LEU B:132 B:132 88.0 0.518 -179.5 360.0 NA NA NA
1pw6 1 P60568 100.0 2e-95 X-RAY
 2004-01-13 LEU A:132 A:132 NA NA NA NA NA NA NA NA
LEU B:132 B:132 44.0 0.259 T -93.5 21.5 NA NA NA
1z92 1 P60568 100.0 2e-95 X-RAY
 2005-06-07 LEU A:132 A:132 52.0 0.306 -64.6 43.9 52.0 0.306 0.0
2b5i 1 P60568 100.0 2e-95 X-RAY
 2005-11-29 LEU A:132 A:132 34.0 0.2 H -54.0 -21.6 34.0 0.2 0.0 HOH
 5.599
 O
 O
5utz 3 P60568 100.0 2e-95 X-RAY
 2018-07-11 LEU C:132 D:132 57.0 0.335 H -74.3 -10.7 57.0 0.335 0.0
LEU F:132 A:132 48.0 0.282 H -75.3 -11.0 NA NA NA
LEU I:132 E:132 57.0 0.335 H -74.3 -11.0 NA NA NA
LEU L:132 I:132 65.0 0.382 H -75.4 -11.2 NA NA NA
7dr4 3 P60568 100.0 2e-95 X-RAY
 2021-04-14 LEU I:132 G:132 81.0 0.476 T -77.2 7.6 NA NA NA
LEU J:132 I:132 80.0 0.471 T -82.1 1.6 NA NA NA
LEU K:132 J:132 50.0 0.294 H -92.3 -10.1 NA NA NA
LEU L:132 K:132 68.0 0.4 T -78.7 6.5 68.0 0.4 0.0
1py2 1 P60568 100.0 7e-95 X-RAY
 2004-01-13 LEU A:132 A:132 118.0 0.694 -151.8 360.0 118.0 0.694 0.0
LEU B:132 B:132 85.0 0.5 -96.8 360.0 NA NA NA
LEU C:132 NA:NA DO NA DO DO DO NA NA NA
LEU D:132 D:132 77.0 0.453 -78.2 360.0 NA NA NA
2erj 4 P60568 99.25 1e-94 X-RAY
 2006-02-21 LEU D:132 D:132 32.0 0.188 H -70.8 -18.0 32.0 0.188 0.0
LEU H:132 H:132 38.0 0.224 H -80.7 -25.6 NA NA NA
3ink 1 P60568 99.25 1e-94 X-RAY
 1993-10-31 LEU A:132 C:132 45.0 0.265 -88.3 26.6 45.0 0.265 0.0
LEU B:132 D:132 62.0 0.365 H -95.4 -25.3 62.0 0.365 0.0
1qvn 1 P60568 99.24 3e-94 X-RAY
 2005-04-05 LEU A:132 A:132 90.0 0.529 -150.5 360.0 90.0 0.529 0.0
LEU B:132 B:132 89.0 0.524 -152.2 360.0 NA NA NA
LEU C:132 C:132 79.0 0.465 -137.3 360.0 79.0 0.465 0.0
LEU D:132 D:132 82.0 0.482 -120.6 360.0 NA NA NA
1m4b 1 P60568 99.25 4e-94 X-RAY
 2002-07-31 LEU A:132 A:132 43.0 0.253 T -96.2 27.6 43.0 0.253 0.0
1m4a 1 P60568 99.25 6e-94 X-RAY
 2002-07-31 LEU A:132 A:132 70.0 0.412 -123.3 360.0 70.0 0.412 0.0
1nbp 1 P60568 99.25 6e-94 X-RAY
 2002-12-18 LEU A:132 A:132 45.0 0.265 T -113.5 -11.5 45.0 0.265 0.0 HOH
 6.939
 C
 O
5lqb 1 P60568 99.24 9e-94 X-RAY
 2016-12-14 LEU A:131 A:152 33.0 0.194 -71.6 86.6 33.0 0.194 0.0 HOH
 3.038
 CD1
 O
7m2g 1 P60568 98.5 3e-93 X-RAY
 2021-08-04 LEU A:132 A:152 74.0 0.435 -81.0 360.0 74.0 0.435 0.0 HOH
 3.163
 O
 O
4nej 1 Q6QWN0 99.23 8e-92 X-RAY
 2014-11-19 LEU A:129 A:132 54.0 0.318 T -116.1 -9.6 54.0 0.318 0.0 2K1
HOH
 8.471
4.290
 O
CD2
 O1
O
4nem 1 Q6QWN0 99.23 8e-92 X-RAY
 2014-11-19 LEU A:129 A:132 45.0 0.265 T -122.1 9.4 45.0 0.265 0.0
5m5e 3 ? 90.6 8e-71 X-RAY
 2017-05-03 LEU C:151 D:132 43.0 0.253 H -76.9 -23.8 43.0 0.253 0.0 HOH
 7.719
 CD2
 O
3qaz 1 P60568 94.07 9e-71 X-RAY
 2012-04-11 LEU A:135 A:132 54.0 0.318 -107.7 146.8 54.0 0.318 0.0
LEU D:135 D:132 50.0 0.294 T -91.8 3.1 NA NA NA
LEU G:135 G:132 52.0 0.306 T -92.8 13.5 NA NA NA
LEU J:135 J:132 41.0 0.241 T -52.7 -14.5 NA NA NA
LEU M:135 M:132 48.0 0.282 T -58.4 4.9 NA NA NA
LEU P:135 P:132 42.0 0.247 -81.1 154.3 NA NA NA
LEU S:135 S:132 53.0 0.312 T -90.6 7.3 NA NA NA
LEU V:135 V:132 40.0 0.235 T -65.2 -39.8 NA NA NA
LEU Y:135 Y:132 99.0 0.582 -92.3 360.0 NA NA NA
LEU BA:135 NA:NA DO NA DO DO DO NA NA NA
LEU EA:135 e:132 54.0 0.318 T -78.0 0.1 NA NA NA
LEU HA:135 h:132 50.0 0.294 T -81.1 -0.5 NA NA NA
3qb1 1 P60568 94.07 9e-71 X-RAY
 2012-04-11 LEU A:135 A:132 58.0 0.341 T -92.9 16.1 58.0 0.341 0.0
LEU B:135 B:132 53.0 0.312 T -93.9 15.8 NA NA NA
LEU C:135 C:132 56.0 0.329 T -92.6 17.3 NA NA NA
LEU D:135 D:132 57.0 0.335 T -92.1 14.0 NA NA NA
LEU E:135 E:132 55.0 0.324 T -90.8 17.4 NA NA NA
LEU F:135 F:132 55.0 0.324 T -93.0 14.5 NA NA NA
LEU G:135 G:132 55.0 0.324 T -94.3 14.1 NA NA NA
LEU H:135 H:132 53.0 0.312 T -93.2 14.3 NA NA NA
6vwu 1 Q6QWN0,P60568,P01589 98.31 2e-34 X-RAY
 2020-04-29 LEU A:58 A:58 40.0 0.235 -78.9 63.4 40.0 0.235 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60568-f1 1 P60568 100.0 6e-111 LEU A:152 A:152 51.0 0.3 H -93.8 -16.9