Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 123377316 . A C CCDS3726.1:NM_000586.3:c.190Ttt>Gtt_NP_000577.2:p.64F>V Homo sapiens interleukin 2 (IL2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6ye3 3 P60568 100.0 1e-95 X-RAY
 2020-12-30 PHE C:45 C:39 1.0 0.005 B -114.9 141.9 1.0 0.005 0.0 HOH
 7.981
 O
 O
PHE F:45 F:39 2.0 0.01 E -109.2 138.9 NA NA NA
PHE I:45 I:39 1.0 0.005 E -115.3 135.9 NA NA NA
1m47 1 P60568 100.0 2e-95 X-RAY
 2002-07-31 PHE A:44 A:44 1.0 0.005 B -118.0 148.6 1.0 0.005 0.0 HOH
 3.687
 CA
 O
1m48 1 P60568 100.0 2e-95 X-RAY
 2002-07-31 PHE A:44 A:44 0.0 0.0 B -117.2 146.4 0.0 0.0 0.0 FRG
HOH
 3.656
4.020
 CA
O
 N32
O
PHE B:44 B:44 0.0 0.0 B -118.8 149.8 NA NA NA
1m49 1 P60568 100.0 2e-95 X-RAY
 2002-07-31 PHE A:44 A:44 0.0 0.0 B -117.8 150.1 0.0 0.0 0.0 CMM
HOH
 3.735
4.209
 CA
CE1
 N40
O
PHE B:44 B:44 0.0 0.0 B -123.8 148.6 NA NA NA
1m4c 1 P60568 100.0 2e-95 X-RAY
 2002-07-31 PHE A:44 A:44 5.0 0.024 B -119.3 163.3 5.0 0.024 0.0
PHE B:44 B:44 4.0 0.019 B -120.0 163.2 NA NA NA
1pw6 1 P60568 100.0 2e-95 X-RAY
 2004-01-13 PHE A:44 A:44 1.0 0.005 B -117.4 150.4 1.0 0.005 0.0 SO4
FRB
 8.610
4.032
 C
CA
 O4
N3
PHE B:44 B:44 0.0 0.0 B -113.8 144.8 NA NA NA
1z92 1 P60568 100.0 2e-95 X-RAY
 2005-06-07 PHE A:44 A:44 5.0 0.024 E -104.0 152.2 0.0 0.0 0.024 B:P01589:0.024
2b5i 1 P60568 100.0 2e-95 X-RAY
 2005-11-29 PHE A:44 A:44 4.0 0.019 B -98.0 148.7 0.0 0.0 0.019 D:P01589:0.019
 HOH
 3.623
 CD2
 O
5utz 3 P60568 100.0 2e-95 X-RAY
 2018-07-11 PHE C:44 D:44 0.0 0.0 B -115.5 143.0 0.0 0.0 0.0 HOH
 3.525
 CE2
 O
PHE F:44 A:44 1.0 0.005 E -114.4 142.2 NA NA NA
PHE I:44 E:44 0.0 0.0 E -114.5 140.6 NA NA NA
PHE L:44 I:44 3.0 0.014 E -113.2 143.8 NA NA NA
7dr4 3 P60568 100.0 2e-95 X-RAY
 2021-04-14 PHE I:44 G:44 1.0 0.005 E -113.5 145.4 NA NA NA
PHE J:44 I:44 0.0 0.0 E -107.7 158.8 NA NA NA
PHE K:44 J:44 0.0 0.0 B -109.8 141.5 NA NA NA
PHE L:44 K:44 1.0 0.005 E -115.6 144.1 1.0 0.005 0.0 HOH
 4.163
 CE2
 O
1py2 1 P60568 100.0 7e-95 X-RAY
 2004-01-13 PHE A:44 A:44 2.0 0.01 B -122.0 147.6 2.0 0.01 0.0 FRH
 3.634
 CA
 N4
PHE B:44 B:44 2.0 0.01 B -133.1 150.5 NA NA NA
PHE C:44 C:44 1.0 0.005 B -112.6 154.2 NA NA NA
PHE D:44 D:44 1.0 0.005 B -116.1 145.2 NA NA NA
2erj 4 P60568 99.25 1e-94 X-RAY
 2006-02-21 PHE D:44 D:44 5.0 0.024 B -109.0 154.1 0.0 0.0 0.024 A:P01589:0.024
PHE H:44 H:44 5.0 0.024 B -113.3 137.8 NA NA NA
3ink 1 P60568 99.25 1e-94 X-RAY
 1993-10-31 PHE A:44 C:44 2.0 0.01 E -118.2 139.8 2.0 0.01 0.0
PHE B:44 D:44 1.0 0.005 B -136.5 143.2 1.0 0.005 0.0
1qvn 1 P60568 99.24 3e-94 X-RAY
 2005-04-05 PHE A:44 A:44 1.0 0.005 B -119.5 157.2 1.0 0.005 0.0 FRI
 4.232
 CA
 N5
PHE B:44 B:44 1.0 0.005 B -124.5 153.1 NA NA NA
PHE C:44 C:44 1.0 0.005 B -117.0 148.8 1.0 0.005 0.0 FRI
 3.770
 CA
 N5
PHE D:44 D:44 1.0 0.005 B -120.9 143.6 NA NA NA
1m4b 1 P60568 99.25 4e-94 X-RAY
 2002-07-31 PHE A:44 A:44 0.0 0.0 B -118.1 150.1 0.0 0.0 0.0 NMP
HOH
 3.809
3.747
 CA
O
 N3
O
1m4a 1 P60568 99.25 6e-94 X-RAY
 2002-07-31 PHE A:44 A:44 2.0 0.01 B -115.0 149.2 2.0 0.01 0.0 MPE
HOH
 8.438
3.850
 CZ
CE1
 C17
O
1nbp 1 P60568 99.25 6e-94 X-RAY
 2002-12-18 PHE A:44 A:44 1.0 0.005 B -121.5 143.7 1.0 0.005 0.0 HOH
 3.565
 CA
 O
5lqb 1 P60568 99.24 9e-94 X-RAY
 2016-12-14 PHE A:43 A:64 2.0 0.01 B -102.1 140.1 2.0 0.01 0.0 HOH
 3.342
 CA
 O
7m2g 1 P60568 98.5 3e-93 X-RAY
 2021-08-04 PHE A:44 A:64 0.0 0.0 B -97.0 140.1 0.0 0.0 0.0 HOH
 3.784
 CE1
 O
4nej 1 Q6QWN0 99.23 8e-92 X-RAY
 2014-11-19 PHE A:41 A:44 4.0 0.019 B -119.8 140.3 4.0 0.019 0.0 2K1
HOH
 3.430
3.718
 CZ
CA
 C
O
4nem 1 Q6QWN0 99.23 8e-92 X-RAY
 2014-11-19 PHE A:41 A:44 2.0 0.01 B -118.2 141.8 2.0 0.01 0.0 HOH
 3.909
 CE2
 O
5m5e 3 ? 90.6 8e-71 X-RAY
 2017-05-03 PHE C:63 D:44 1.0 0.005 B -119.6 139.8 1.0 0.005 0.0 HOH
 4.429
 CE1
 O
3qaz 1 P60568 94.07 9e-71 X-RAY
 2012-04-11 PHE A:47 A:44 4.0 0.019 E -86.0 161.8 4.0 0.019 0.0
PHE D:47 D:44 3.0 0.014 E -87.5 159.3 NA NA NA
PHE G:47 G:44 3.0 0.014 E -90.3 164.1 NA NA NA
PHE J:47 J:44 1.0 0.005 B -99.9 150.6 NA NA NA
PHE M:47 M:44 3.0 0.014 B -79.9 159.9 NA NA NA
PHE P:47 P:44 3.0 0.014 B -89.6 131.0 NA NA NA
PHE S:47 S:44 6.0 0.029 E -111.7 163.3 NA NA NA
PHE V:47 V:44 6.0 0.029 B -119.6 166.3 NA NA NA
PHE Y:47 Y:44 4.0 0.019 E -123.8 168.4 NA NA NA
PHE BA:47 b:44 2.0 0.01 B -125.9 145.5 NA NA NA
PHE EA:47 e:44 5.0 0.024 B -113.0 147.9 NA NA NA
PHE HA:47 h:44 3.0 0.014 B -104.8 155.7 NA NA NA
3qb1 1 P60568 94.07 9e-71 X-RAY
 2012-04-11 PHE A:47 A:44 1.0 0.005 E -111.9 150.7 1.0 0.005 0.0
PHE B:47 B:44 1.0 0.005 E -112.9 150.4 NA NA NA
PHE C:47 C:44 2.0 0.01 E -117.9 152.3 NA NA NA
PHE D:47 D:44 0.0 0.0 E -111.8 149.7 NA NA NA
PHE E:47 E:44 1.0 0.005 E -114.5 152.9 NA NA NA
PHE F:47 F:44 0.0 0.0 E -112.5 151.6 NA NA NA
PHE G:47 G:44 0.0 0.0 E -113.4 151.0 NA NA NA
PHE H:47 H:44 0.0 0.0 E -113.1 152.6 NA NA NA
6vwu 1 Q6QWN0,P60568,P01589 82.95 2e-23 X-RAY
 2020-04-29 PHE A:102 A:102 0.0 0.0 B -101.3 162.7 0.0 0.0 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p60568-f1 1 P60568 100.0 6e-111 PHE A:64 A:64 0.0 0.0 E -100.2 145.8