Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr4 | 123377467 | . | C | A | CCDS3726.1:NM_000586.3:c.129atG>atT_NP_000577.2:p.43M>I | Homo sapiens interleukin 2 (IL2), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6ye3 | 3 | P60568 | 100.0 | 1e-95 |
X-RAY |
2020-12-30 | MET | C:24 | C:18 | 78.0 | 0.422 | H | -61.3 | -40.0 | 78.0 | 0.422 | 0.0 |
HOH |
7.850 |
O |
O |
||
MET | F:24 | F:18 | 115.0 | 0.622 | H | -64.7 | -35.6 | NA | NA | NA | |||||||||||||
MET | I:24 | I:18 | 96.0 | 0.519 | H | -60.0 | -45.7 | NA | NA | NA | |||||||||||||
1m47 | 1 | P60568 | 100.0 | 2e-95 |
X-RAY |
2002-07-31 | MET | A:23 | A:23 | 65.0 | 0.351 | H | -63.1 | -37.4 | 65.0 | 0.351 | 0.0 |
HOH |
3.155 |
CE |
O |
||
1m48 | 1 | P60568 | 100.0 | 2e-95 |
X-RAY |
2002-07-31 | MET | A:23 | A:23 | 133.0 | 0.719 | H | -66.6 | -41.8 | 133.0 | 0.719 | 0.0 |
HOH |
3.093 |
CG |
O |
||
MET | B:23 | B:23 | 100.0 | 0.541 | H | -65.5 | -36.7 | NA | NA | NA | |||||||||||||
1m49 | 1 | P60568 | 100.0 | 2e-95 |
X-RAY |
2002-07-31 | MET | A:23 | A:23 | 138.0 | 0.746 | H | -70.7 | -40.4 | 138.0 | 0.746 | 0.0 |
HOH |
4.640 |
N |
O |
||
MET | B:23 | B:23 | 98.0 | 0.53 | H | -66.8 | -38.4 | NA | NA | NA | |||||||||||||
1m4c | 1 | P60568 | 100.0 | 2e-95 |
X-RAY |
2002-07-31 | MET | A:23 | A:23 | 106.0 | 0.573 | H | -68.1 | -35.6 | 106.0 | 0.573 | 0.0 | ||||||
MET | B:23 | B:23 | 105.0 | 0.568 | H | -67.4 | -36.6 | NA | NA | NA | |||||||||||||
1pw6 | 1 | P60568 | 100.0 | 2e-95 |
X-RAY |
2004-01-13 | MET | A:23 | A:23 | 118.0 | 0.638 | H | -60.5 | -48.5 | 118.0 | 0.638 | 0.0 | ||||||
MET | B:23 | B:23 | 84.0 | 0.454 | H | -56.8 | -50.3 | NA | NA | NA | |||||||||||||
1z92 | 1 | P60568 | 100.0 | 2e-95 |
X-RAY |
2005-06-07 | MET | A:23 | A:23 | 114.0 | 0.616 | H | -58.1 | -41.7 | 114.0 | 0.616 | 0.0 | ||||||
2b5i | 1 | P60568 | 100.0 | 2e-95 |
X-RAY |
2005-11-29 | MET | A:23 | A:23 | 86.0 | 0.465 | H | -55.9 | -51.4 | 55.0 | 0.297 | 0.168 |
B:P14784:0.168 |
HOH |
5.655 |
SD |
O |
|
5utz | 3 | P60568 | 100.0 | 2e-95 |
X-RAY |
2018-07-11 | MET | C:23 | D:23 | 96.0 | 0.519 | H | -62.7 | -43.8 | 5.0 | 0.027 | 0.492 |
A:Q6GMX6:0.492 |
HOH |
3.574 |
N |
O |
|
MET | F:23 | A:23 | 81.0 | 0.438 | H | -62.9 | -43.2 | NA | NA | NA | |||||||||||||
MET | I:23 | E:23 | 81.0 | 0.438 | H | -62.9 | -43.4 | NA | NA | NA | |||||||||||||
MET | L:23 | I:23 | 85.0 | 0.459 | H | -62.9 | -43.5 | NA | NA | NA | |||||||||||||
7dr4 | 3 | P60568 | 100.0 | 2e-95 |
X-RAY |
2021-04-14 | MET | I:23 | G:23 | 70.0 | 0.378 | H | -63.8 | -47.2 | NA | NA | NA | ||||||
MET | J:23 | I:23 | 86.0 | 0.465 | H | -64.9 | -49.7 | NA | NA | NA | |||||||||||||
MET | K:23 | J:23 | 72.0 | 0.389 | H | -65.2 | -41.9 | NA | NA | NA | |||||||||||||
MET | L:23 | K:23 | 64.0 | 0.346 | H | -66.3 | -45.8 | 64.0 | 0.346 | 0.0 | |||||||||||||
1py2 | 1 | P60568 | 100.0 | 7e-95 |
X-RAY |
2004-01-13 | MET | A:23 | A:23 | 103.0 | 0.557 | H | -68.6 | -35.4 | 103.0 | 0.557 | 0.0 | ||||||
MET | B:23 | B:23 | 123.0 | 0.665 | H | -60.0 | -47.3 | NA | NA | NA | |||||||||||||
MET | C:23 | C:23 | 115.0 | 0.622 | H | -66.0 | -42.0 | NA | NA | NA | |||||||||||||
MET | D:23 | D:23 | 106.0 | 0.573 | H | -71.2 | -36.0 | NA | NA | NA | |||||||||||||
2erj | 4 | P60568 | 99.25 | 1e-94 |
X-RAY |
2006-02-21 | MET | D:23 | D:23 | 95.0 | 0.514 | H | -74.7 | -35.4 | 59.0 | 0.319 | 0.195 |
B:P14784:0.195 |
|||||
MET | H:23 | H:23 | 104.0 | 0.562 | H | -64.4 | -37.3 | NA | NA | NA | |||||||||||||
3ink | 1 | P60568 | 99.25 | 1e-94 |
X-RAY |
1993-10-31 | MET | A:23 | C:23 | 40.0 | 0.216 | H | -71.5 | -25.8 | 40.0 | 0.216 | 0.0 | ||||||
MET | B:23 | D:23 | 32.0 | 0.173 | H | -68.1 | -30.3 | 32.0 | 0.173 | 0.0 | |||||||||||||
1qvn | 1 | P60568 | 99.24 | 3e-94 |
X-RAY |
2005-04-05 | MET | A:23 | A:23 | 108.0 | 0.584 | H | -66.7 | -48.1 | 108.0 | 0.584 | 0.0 |
ZN |
5.574 |
CE |
ZN |
||
MET | B:23 | B:23 | 112.0 | 0.605 | H | -62.6 | -45.5 | NA | NA | NA | |||||||||||||
MET | C:23 | C:23 | 112.0 | 0.605 | H | -69.9 | -43.2 | 112.0 | 0.605 | 0.0 | |||||||||||||
MET | D:23 | D:23 | 114.0 | 0.616 | H | -71.2 | -35.4 | NA | NA | NA | |||||||||||||
1m4b | 1 | P60568 | 99.25 | 4e-94 |
X-RAY |
2002-07-31 | MET | A:23 | A:23 | 110.0 | 0.595 | H | -59.0 | -38.9 | 110.0 | 0.595 | 0.0 |
HOH |
5.101 |
CE |
O |
||
1m4a | 1 | P60568 | 99.25 | 6e-94 |
X-RAY |
2002-07-31 | MET | A:23 | A:23 | 72.0 | 0.389 | H | -69.2 | -32.6 | 72.0 | 0.389 | 0.0 |
MPE HOH |
9.834 3.536 |
O CE |
S1 O |
||
1nbp | 1 | P60568 | 99.25 | 6e-94 |
X-RAY |
2002-12-18 | MET | A:23 | A:23 | 83.0 | 0.449 | H | -58.3 | -43.9 | 83.0 | 0.449 | 0.0 |
MHC HOH |
4.465 3.403 |
O CA |
C15 O |
||
5lqb | 1 | P60568 | 99.24 | 9e-94 |
X-RAY |
2016-12-14 | MET | A:22 | A:43 | 35.0 | 0.189 | H | -61.7 | -47.2 | 35.0 | 0.189 | 0.0 |
HOH |
2.931 |
O |
O |
||
7m2g | 1 | P60568 | 98.5 | 3e-93 |
X-RAY |
2021-08-04 | MET | A:23 | A:43 | 67.0 | 0.362 | H | -57.2 | -44.0 | 67.0 | 0.362 | 0.0 |
HOH |
2.681 |
O |
O |
||
4nej | 1 | Q6QWN0 | 99.23 | 8e-92 |
X-RAY |
2014-11-19 | MET | A:20 | A:23 | 111.0 | 0.6 | H | -59.2 | -40.0 | 111.0 | 0.6 | 0.0 |
HOH |
2.773 |
O |
O |
||
4nem | 1 | Q6QWN0 | 99.23 | 8e-92 |
X-RAY |
2014-11-19 | MET | A:20 | A:23 | 96.0 | 0.519 | H | -62.8 | -39.2 | 96.0 | 0.519 | 0.0 |
HOH |
3.832 |
O |
O |
||
5m5e | 3 | ? | 90.6 | 8e-71 |
X-RAY |
2017-05-03 | MET | C:42 | D:23 | 105.0 | 0.568 | H | -69.3 | -40.2 | 68.0 | 0.368 | 0.2 |
A:P14784:0.2 |
HOH |
3.190 |
CE |
O |
|
3qaz | 1 | P60568 | 94.07 | 9e-71 |
X-RAY |
2012-04-11 | MET | A:26 | A:23 | 67.0 | 0.362 | H | -62.6 | -38.3 | 35.0 | 0.189 | 0.173 |
B:P14784:0.173 |
|||||
MET | D:26 | D:23 | 73.0 | 0.395 | H | -54.7 | -35.6 | NA | NA | NA | |||||||||||||
MET | G:26 | G:23 | 64.0 | 0.346 | H | -46.8 | -58.4 | NA | NA | NA | |||||||||||||
MET | J:26 | J:23 | 72.0 | 0.389 | H | -60.7 | -30.3 | NA | NA | NA | |||||||||||||
MET | M:26 | M:23 | 65.0 | 0.351 | H | -55.2 | -59.8 | NA | NA | NA | |||||||||||||
MET | P:26 | P:23 | 66.0 | 0.357 | H | -66.0 | -43.0 | NA | NA | NA | |||||||||||||
MET | S:26 | S:23 | 70.0 | 0.378 | H | -68.1 | -35.8 | NA | NA | NA | |||||||||||||
MET | V:26 | V:23 | 70.0 | 0.378 | H | -70.9 | -28.1 | NA | NA | NA | |||||||||||||
MET | Y:26 | Y:23 | 72.0 | 0.389 | H | -71.2 | -28.8 | NA | NA | NA | |||||||||||||
MET | BA:26 | b:23 | 69.0 | 0.373 | H | -54.1 | -33.8 | NA | NA | NA | |||||||||||||
MET | EA:26 | e:23 | 74.0 | 0.4 | H | -62.9 | -37.0 | NA | NA | NA | |||||||||||||
MET | HA:26 | h:23 | 67.0 | 0.362 | H | -52.4 | -43.4 | NA | NA | NA | |||||||||||||
3qb1 | 1 | P60568 | 94.07 | 9e-71 |
X-RAY |
2012-04-11 | MET | A:26 | A:23 | 70.0 | 0.378 | H | -63.0 | -43.1 | 70.0 | 0.378 | 0.0 | ||||||
MET | B:26 | B:23 | 67.0 | 0.362 | H | -66.8 | -42.1 | NA | NA | NA | |||||||||||||
MET | C:26 | C:23 | 70.0 | 0.378 | H | -68.8 | -41.2 | NA | NA | NA | |||||||||||||
MET | D:26 | D:23 | 69.0 | 0.373 | H | -67.6 | -39.9 | NA | NA | NA | |||||||||||||
MET | E:26 | E:23 | 70.0 | 0.378 | H | -69.4 | -40.8 | NA | NA | NA | |||||||||||||
MET | F:26 | F:23 | 69.0 | 0.373 | H | -64.6 | -41.4 | NA | NA | NA | |||||||||||||
MET | G:26 | G:23 | 70.0 | 0.378 | H | -62.4 | -42.3 | NA | NA | NA | |||||||||||||
MET | H:26 | H:23 | 68.0 | 0.368 | H | -65.3 | -40.3 | NA | NA | NA | |||||||||||||
6vwu | 1 | Q6QWN0,P60568,P01589 | 82.95 | 2e-23 |
X-RAY |
2020-04-29 | MET | A:81 | A:81 | 51.0 | 0.276 | H | -65.3 | -43.6 | 51.0 | 0.276 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p60568-f1 | 1 | P60568 | 100.0 | 6e-111 | MET | A:43 | A:43 | 91.0 | 0.492 | H | -62.1 | -44.0 |