Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 128811336 . C A CCDS3735.1:NM_014264.4:c.1775tCt>tAt_NP_055079.3:p.592S>Y Homo sapiens polo like kinase 4 (PLK4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4n7v 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 SER A:13 A:592 88.0 0.765 -111.3 150.5 88.0 0.765 0.0
SER B:13 B:592 84.0 0.73 -74.7 149.8 84.0 0.73 0.0
4n7z 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 SER A:13 A:592 92.0 0.8 -94.2 155.2 92.0 0.8 0.0 HOH
 6.748
 C
 O
4n9j 1 O00444 100.0 5e-163 X-RAY
 2014-07-02 SER A:12 A:592 87.0 0.757 -99.5 153.1 87.0 0.757 0.0 HOH
 3.543
 N
 O
SER B:12 B:592 83.0 0.722 -101.9 152.5 83.0 0.722 0.0 HOH
 3.294
 N
 O
6n45 1 O00444,Q9Y4B6 97.4 2e-160 X-RAY
 2019-09-04 SER A:16 A:592 77.0 0.67 -125.7 158.4 77.0 0.67 0.0
SER B:16 B:592 86.0 0.748 -84.5 158.4 86.0 0.748 0.0
6n46 1 O00444 98.25 1e-159 X-RAY
 2019-09-04 SER A:33 A:7 75.0 0.652 -72.2 160.5 75.0 0.652 0.0
SER B:33 B:7 90.0 0.783 -71.5 159.9 90.0 0.783 0.0
SER C:33 C:7 76.0 0.661 -70.5 160.4 NA NA NA
SER D:33 D:7 90.0 0.783 -73.4 156.1 NA NA NA
SER E:33 E:7 75.0 0.652 -71.3 157.6 NA NA NA
SER F:33 F:7 81.0 0.704 -72.4 162.6 NA NA NA
SER G:33 G:7 68.0 0.591 -70.8 160.2 NA NA NA
SER H:33 H:7 78.0 0.678 -70.7 161.1 NA NA NA
6w38 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 SER B:8 B:592 73.0 0.635 -93.9 154.5 73.0 0.635 0.0
6w3i 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 SER B:8 B:592 86.0 0.748 -72.6 155.2 86.0 0.748 0.0
6w3j 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 SER B:8 B:592 73.0 0.635 -93.6 154.5 73.0 0.635 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o00444-f1 1 O00444 100.0 0.0 SER A:592 A:592 77.0 0.67 -76.7 169.8