Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 128811357 . T A CCDS3735.1:NM_014264.4:c.1796tTa>tAa_NP_055079.3:p.599L>* Homo sapiens polo like kinase 4 (PLK4), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4n7v 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 LEU A:20 A:599 6.0 0.035 -79.5 147.9 4.0 0.024 0.011 B:O00444:0.012
LEU B:20 B:599 7.0 0.041 -77.5 137.3 6.0 0.035 0.006 A:O00444:0.006
4n7z 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 LEU A:20 A:599 6.0 0.035 -95.0 128.8 4.0 0.024 0.011 A:O00444:0.012
 HOH
 3.482
 CA
 O
4n9j 1 O00444 100.0 5e-163 X-RAY
 2014-07-02 LEU A:19 A:599 8.0 0.047 -70.6 138.5 6.0 0.035 0.012 B:O00444:0.012
 HOH
 3.635
 CA
 O
LEU B:19 B:599 9.0 0.053 -73.6 140.4 7.0 0.041 0.012 A:O00444:0.012
 HOH
 5.633
 N
 O
6n45 1 O00444,Q9Y4B6 97.4 2e-160 X-RAY
 2019-09-04 LEU A:23 A:599 5.0 0.029 -96.7 126.5 5.0 0.029 0.0
LEU B:23 B:599 2.0 0.012 -89.1 125.2 2.0 0.012 0.0
6n46 1 O00444 98.25 1e-159 X-RAY
 2019-09-04 LEU A:40 A:14 13.0 0.076 -108.8 145.1 13.0 0.076 0.0
LEU B:40 B:14 13.0 0.076 -107.4 143.9 13.0 0.076 0.0
LEU C:40 C:14 13.0 0.076 -107.8 146.7 NA NA NA
LEU D:40 D:14 12.0 0.071 -107.2 143.8 NA NA NA
LEU E:40 E:14 11.0 0.065 -105.1 151.8 NA NA NA
LEU F:40 F:14 15.0 0.088 -107.6 149.8 NA NA NA
LEU G:40 G:14 10.0 0.059 -105.7 145.6 NA NA NA
LEU H:40 H:14 14.0 0.082 -107.3 147.1 NA NA NA
6w38 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 LEU B:15 B:599 6.0 0.035 -94.2 128.9 6.0 0.035 0.0
6w3i 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 LEU B:15 B:599 12.0 0.071 -92.9 132.7 12.0 0.071 0.0
6w3j 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 LEU B:15 B:599 6.0 0.035 -93.8 128.4 6.0 0.035 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o00444-f1 1 O00444 100.0 0.0 LEU A:599 A:599 7.0 0.041 -78.8 139.2