Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 128812820 . C A CCDS3735.1:NM_014264.4:c.2022agC>agA_NP_055079.3:p.674S>R Homo sapiens polo like kinase 4 (PLK4), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4n7v 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 SER A:95 A:674 50.0 0.435 E -78.7 169.8 50.0 0.435 0.0 HOH
 2.749
 N
 O
SER B:95 B:674 49.0 0.426 E -78.9 175.5 49.0 0.426 0.0
4n7z 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 SER A:95 A:674 62.0 0.539 E -104.0 148.4 62.0 0.539 0.0 HOH
 2.899
 OG
 O
4n9j 1 O00444 100.0 5e-163 X-RAY
 2014-07-02 SER A:94 A:674 57.0 0.496 E -77.1 159.5 57.0 0.496 0.0 HOH
 3.229
 OG
 O
SER B:94 B:674 46.0 0.4 E -75.9 161.1 46.0 0.4 0.0 HOH
 2.815
 OG
 O
6n45 1 O00444,Q9Y4B6 97.4 2e-160 X-RAY
 2019-09-04 SER A:98 A:674 46.0 0.4 E -81.0 156.9 46.0 0.4 0.0
SER B:98 B:674 35.0 0.304 E -89.5 161.2 35.0 0.304 0.0
6n46 1 O00444 98.25 1e-159 X-RAY
 2019-09-04 SER A:115 A:89 49.0 0.426 E -88.1 165.7 49.0 0.426 0.0
SER B:115 B:89 44.0 0.383 E -89.8 164.1 44.0 0.383 0.0
SER C:115 C:89 49.0 0.426 E -88.6 164.6 NA NA NA
SER D:115 D:89 46.0 0.4 E -91.3 163.6 NA NA NA
SER E:115 E:89 52.0 0.452 E -89.4 165.3 NA NA NA
SER F:115 F:89 45.0 0.391 E -90.4 162.7 NA NA NA
SER G:115 G:89 51.0 0.443 E -90.7 163.2 NA NA NA
SER H:115 H:89 46.0 0.4 E -91.8 164.3 NA NA NA
6w38 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 SER B:90 B:674 51.0 0.443 E -103.3 149.2 6.0 0.052 0.391 A:Q5VWP2:0.391
6w3i 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 SER B:90 B:674 43.0 0.374 E -86.8 169.9 9.0 0.078 0.296 A:Q5VWP2:0.296
6w3j 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 SER B:90 B:674 55.0 0.478 E -104.4 147.8 5.0 0.043 0.435 A:Q5VWP2:0.435

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o00444-f1 1 O00444 100.0 0.0 SER A:674 A:674 48.0 0.417 E -87.6 164.3