Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 128813526 . A C CCDS3735.1:NM_014264.4:c.2045tAc>tCc_NP_055079.3:p.682Y>S Homo sapiens polo like kinase 4 (PLK4), transcript variant 1, mRNA.
pdb_id: 
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label_comp_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4n7v 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 TYR A:103 A:682 24.0 0.104 T 71.3 -14.5 20.0 0.087 0.017 C:O94986:0.017
TYR B:103 B:682 39.0 0.17 S 62.4 16.7 39.0 0.17 0.0
4n7z 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 TYR A:103 A:682 13.0 0.057 H -99.9 -13.7 13.0 0.057 0.0 HOH
 3.929
 CE1
 O
4n9j 1 O00444 100.0 5e-163 X-RAY
 2014-07-02 TYR A:102 A:682 8.0 0.035 G -115.4 -5.1 8.0 0.035 0.0 HOH
 4.660
 CE2
 O
TYR B:102 B:682 8.0 0.035 G -113.0 -5.6 8.0 0.035 0.0 CL
HOH
 3.635
5.806
 OH
N
 CL
O
6n45 1 O00444,Q9Y4B6 97.4 2e-160 X-RAY
 2019-09-04 TYR A:106 A:682 32.0 0.139 G -102.3 -8.8 32.0 0.139 0.0
TYR B:106 B:682 29.0 0.126 G -106.9 -11.5 29.0 0.126 0.0
6n46 1 O00444 98.25 1e-159 X-RAY
 2019-09-04 TYR A:123 A:97 72.0 0.313 T 75.8 -4.4 72.0 0.313 0.0
TYR B:123 B:97 38.0 0.165 T 77.6 -6.1 38.0 0.165 0.0
TYR C:123 C:97 42.0 0.183 T 76.4 -4.4 NA NA NA
TYR D:123 D:97 69.0 0.3 T 77.3 -6.8 NA NA NA
TYR E:123 E:97 28.0 0.122 T 79.1 -4.9 NA NA NA
TYR F:123 F:97 29.0 0.126 T 77.5 -4.1 NA NA NA
TYR G:123 G:97 48.0 0.209 T 77.7 1.1 NA NA NA
TYR H:123 H:97 43.0 0.187 T 77.3 -3.1 NA NA NA
6w38 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 TYR B:98 B:682 26.0 0.113 H -100.8 -13.7 24.0 0.104 0.009 A:Q5VWP2:0.009
6w3i 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 TYR B:98 B:682 11.0 0.048 G -114.1 -8.5 11.0 0.048 0.0
6w3j 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 TYR B:98 B:682 22.0 0.096 H -101.1 -14.4 21.0 0.091 0.005 A:Q5VWP2:0.004

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o00444-f1 1 O00444 100.0 0.0 TYR A:682 A:682 3.0 0.013 G -106.6 -12.3