Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 128813629 . G A CCDS3735.1:NM_014264.4:c.2148gaG>gaA_NP_055079.3:p.716E>E Homo sapiens polo like kinase 4 (PLK4), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4n7v 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 GLU A:137 A:716 3.0 0.016 S -93.2 -10.0 3.0 0.016 0.0 HOH
 7.097
 O
 O
GLU B:137 B:716 10.0 0.053 S -96.1 -8.6 8.0 0.042 0.011 A:O00444:0.011
 HOH
 9.220
 OE2
 O
4n7z 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 GLU A:137 A:716 4.0 0.021 S -86.5 -6.1 4.0 0.021 0.0 HOH
 2.815
 OE2
 O
4n9j 1 O00444 100.0 5e-163 X-RAY
 2014-07-02 GLU A:136 A:716 6.0 0.032 S -96.5 -9.5 5.0 0.026 0.006 B:O00444:0.005
 HOH
 5.758
 OE2
 O
GLU B:136 B:716 7.0 0.037 S -96.6 -12.3 7.0 0.037 0.0 CL
HOH
 5.789
5.619
 OE2
OE2
 CL
O
6n45 1 O00444,Q9Y4B6 97.4 2e-160 X-RAY
 2019-09-04 GLU A:140 A:716 4.0 0.021 S -85.1 -1.6 4.0 0.021 0.0
GLU B:140 B:716 3.0 0.016 S -96.1 11.7 3.0 0.016 0.0
6n46 1 O00444 98.25 1e-159 X-RAY
 2019-09-04 GLU A:157 A:131 2.0 0.011 S -72.9 -16.8 2.0 0.011 0.0
GLU B:157 B:131 1.0 0.005 S -73.4 -18.2 1.0 0.005 0.0
GLU C:157 C:131 2.0 0.011 S -72.8 -16.9 NA NA NA
GLU D:157 D:131 2.0 0.011 S -71.0 -13.1 NA NA NA
GLU E:157 E:131 5.0 0.026 S -73.5 -17.6 NA NA NA
GLU F:157 F:131 2.0 0.011 S -68.6 -12.9 NA NA NA
GLU G:157 G:131 3.0 0.016 S -71.4 -18.6 NA NA NA
GLU H:157 H:131 3.0 0.016 S -69.2 -11.7 NA NA NA
6w38 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 GLU B:132 B:716 6.0 0.032 S -86.8 -6.2 6.0 0.032 0.0
6w3i 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 GLU B:132 B:716 10.0 0.053 S -80.3 -26.9 10.0 0.053 0.0
6w3j 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 GLU B:132 B:716 10.0 0.053 S -86.9 -6.2 10.0 0.053 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o00444-f1 1 O00444 100.0 0.0 GLU A:716 A:716 5.0 0.026 S -78.5 -3.4