Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 128814496 . T A CCDS3735.1:NM_014264.4:c.2245Tct>Act_NP_055079.3:p.749S>T Homo sapiens polo like kinase 4 (PLK4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4n7v 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 SER A:170 A:749 75.0 0.652 E -115.3 143.5 75.0 0.652 0.0 HOH
 8.068
 CB
 O
SER B:170 B:749 63.0 0.548 -168.4 155.4 63.0 0.548 0.0
4n7z 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 SER A:170 A:749 85.0 0.739 E -119.1 124.5 85.0 0.739 0.0
4n9j 1 O00444 100.0 5e-163 X-RAY
 2014-07-02 SER A:169 A:749 68.0 0.591 E -98.0 132.4 68.0 0.591 0.0
SER B:169 B:749 75.0 0.652 E -99.2 132.9 75.0 0.652 0.0
6n45 1 O00444,Q9Y4B6 97.4 2e-160 X-RAY
 2019-09-04 SER A:173 A:749 80.0 0.696 E -118.6 135.1 80.0 0.696 0.0
SER B:173 B:749 83.0 0.722 E -67.4 157.5 83.0 0.722 0.0
6n46 1 O00444 98.25 1e-159 X-RAY
 2019-09-04 SER A:190 A:164 68.0 0.591 E -141.1 153.6 68.0 0.591 0.0
SER B:190 B:164 65.0 0.565 E -143.4 157.5 65.0 0.565 0.0
SER C:190 C:164 68.0 0.591 E -142.2 153.9 NA NA NA
SER D:190 D:164 62.0 0.539 E -142.9 162.0 NA NA NA
SER E:190 E:164 68.0 0.591 E -139.7 151.4 NA NA NA
SER F:190 F:164 84.0 0.73 E -142.8 154.3 NA NA NA
SER G:190 G:164 69.0 0.6 E -139.7 151.6 NA NA NA
SER H:190 H:164 69.0 0.6 E -140.0 150.3 NA NA NA
6w38 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 SER B:165 B:749 84.0 0.73 E -122.1 124.8 84.0 0.73 0.0
6w3i 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 SER B:165 B:749 79.0 0.687 E -141.0 112.3 79.0 0.687 0.0
6w3j 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 SER B:165 B:749 78.0 0.678 -76.0 125.1 78.0 0.678 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o00444-f1 1 O00444 100.0 0.0 SER A:749 A:749 38.0 0.33 E -107.4 132.7