Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 128814746 . A C CCDS3735.1:NM_014264.4:c.2401Ata>Cta_NP_055079.3:p.801I>L Homo sapiens polo like kinase 4 (PLK4), transcript variant 1, mRNA.
pdb_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4n7v 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 ILE A:222 A:801 38.0 0.217 E -124.5 143.6 0.0 0.0 0.217 B:O00444:0.217
 HOH
 6.927
 C
 O
ILE B:222 B:801 33.0 0.189 E -125.2 155.6 1.0 0.006 0.183 A:O00444:0.183
 HOH
 4.451
 CA
 O
4n7z 1 O00444 100.0 2e-164 X-RAY
 2014-07-02 ILE A:222 A:801 43.0 0.246 E -152.4 125.1 3.0 0.017 0.229 A:O00444:0.229
 HOH
 5.125
 N
 O
4n9j 1 O00444 100.0 5e-163 X-RAY
 2014-07-02 ILE A:221 A:801 35.0 0.2 E -129.9 149.1 1.0 0.006 0.194 B:O00444:0.194
 HOH
 3.011
 O
 O
ILE B:221 B:801 54.0 0.309 E -130.7 144.2 4.0 0.023 0.286 A:O00444:0.286
 HOH
 3.005
 O
 O
6n45 1 O00444,Q9Y4B6 97.4 2e-160 X-RAY
 2019-09-04 ILE A:225 A:801 40.0 0.229 E -125.7 151.3 4.0 0.023 0.206 B:O00444+Q9Y4B6:0.206
ILE B:225 B:801 28.0 0.16 E -140.2 136.4 1.0 0.006 0.154 A:O00444+Q9Y4B6:0.154
6n46 1 O00444 98.25 1e-159 X-RAY
 2019-09-04 ILE A:242 A:216 35.0 0.2 E -126.5 149.5 5.0 0.029 0.171 B:O00444:0.171
ILE B:242 B:216 34.0 0.194 E -126.2 149.9 5.0 0.029 0.165 A:O00444:0.166
ILE C:242 C:216 34.0 0.194 E -126.3 149.5 NA NA NA
ILE D:242 D:216 31.0 0.177 E -126.5 150.0 NA NA NA
ILE E:242 E:216 35.0 0.2 E -125.9 148.4 NA NA NA
ILE F:242 F:216 50.0 0.286 E -126.4 146.9 NA NA NA
ILE G:242 G:216 35.0 0.2 E -127.1 149.9 NA NA NA
ILE H:242 H:216 37.0 0.211 E -127.7 150.9 NA NA NA
6w38 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 ILE B:217 B:801 55.0 0.314 E -151.9 124.2 55.0 0.314 0.0
6w3i 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 ILE B:217 B:801 39.0 0.223 E -133.6 144.5 39.0 0.223 0.0
6w3j 2 O00444 100.0 1e-158 X-RAY
 2020-05-06 ILE B:217 B:801 51.0 0.291 E -151.6 124.4 51.0 0.291 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-o00444-f1 1 O00444 100.0 0.0 ILE A:801 A:801 48.0 0.274 E -105.9 147.9