Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 102001706 . T A CCDS34037.1:NM_000944.4:c.938gAt>gTt_NP_000935.1:p.313D>V Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1aui 1 Q08209 100.0 0.0 X-RAY
 1997-12-03 ASP A:313 A:313 96.0 0.64 G 68.9 3.7 96.0 0.64 0.0 HOH
 3.094
 OD1
 O
4orb 1 P63328 97.7 0.0 X-RAY
 2015-05-20 ASP A:313 A:313 96.0 0.64 G 69.5 12.7 96.0 0.64 0.0
4il1 1 P62161,P63100,P63329 97.76 0.0 X-RAY
 2013-10-02 ASP A:646 A:646 84.0 0.56 G 74.0 2.6 84.0 0.56 0.0 HOH
 3.665
 N
 O
ASP B:646 B:646 89.0 0.593 G 72.5 2.6 NA NA NA
ASP C:646 C:646 87.0 0.58 G 73.5 1.5 NA NA NA
ASP D:646 D:646 86.0 0.573 G 74.5 0.9 NA NA NA
4or9 1 P16298 85.63 0.0 X-RAY
 2015-05-20 ASP A:342 A:322 87.0 0.58 G 58.4 13.0 87.0 0.58 0.0 HOH
 2.639
 OD1
 O
4orc 1 P16298 85.63 0.0 X-RAY
 2015-05-20 ASP A:342 A:322 95.0 0.633 G 63.3 -4.9 95.0 0.633 0.0 HOH
 2.800
 OD1
 O
4ora 1 P16298 85.23 0.0 X-RAY
 2015-05-20 ASP A:342 A:322 93.0 0.62 G 62.4 7.8 93.0 0.62 0.0 HOH
 3.247
 OD1
 O
2p6b 2 Q08209 100.0 0.0 X-RAY
 2007-06-05 ASP B:316 A:313 88.0 0.587 G 59.6 16.0 88.0 0.587 0.0 HOH
 2.489
 OD2
 O
ASP D:316 C:313 87.0 0.58 G 61.9 6.1 87.0 0.58 0.0 HOH
 2.710
 OD1
 O
1tco 1 P48452 99.73 0.0 X-RAY
 1997-02-12 ASP A:296 A:313 92.0 0.613 G 61.5 4.8 33.0 0.22 0.393 C:P62942:0.393
 HOH
 2.690
 OD1
 O
1mf8 1 Q08209 100.0 0.0 X-RAY
 2002-10-16 ASP A:294 A:313 94.0 0.627 G 72.4 -0.5 78.0 0.52 0.107 D:NOR00033:0.107
1m63 1 Q08209 100.0 0.0 X-RAY
 2002-09-25 ASP A:313 A:313 85.0 0.567 G 57.1 13.5 60.0 0.4 0.167 D:NOR00033:0.167
ASP E:313 E:313 82.0 0.547 G 53.7 26.4 67.0 0.447 0.1 H:NOR00033:0.1
5sve 1 Q08209 100.0 0.0 X-RAY
 2017-01-11 ASP A:313 A:313 78.0 0.52 G 57.8 20.7 78.0 0.52 0.0 HOH
 4.374
 OD2
 O
4f0z 1 Q08209 100.0 0.0 X-RAY
 2013-03-06 ASP A:315 A:313 93.0 0.62 G 66.4 7.7 78.0 0.52 0.1 C:O36972:0.1
 GOL
GOL
HOH
 9.938
8.597
2.564
 O
OD2
O
 HO1
HO1
O
6nuc 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 ASP A:315 A:313 92.0 0.613 G 61.8 14.2 92.0 0.613 0.0 HOH
 2.617
 OD2
 O
6nuf 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 ASP A:315 A:313 89.0 0.593 G 61.5 11.5 89.0 0.593 0.0 HOH
 2.657
 OD1
 O
6nuu 1 Q08209 99.46 0.0 X-RAY
 2019-07-03 ASP A:315 A:313 86.0 0.573 G 65.2 18.4 86.0 0.573 0.0 HOH
 2.517
 OD1
 O
3ll8 2 Q08209 100.0 0.0 X-RAY
 2011-01-12 ASP B:300 A:313 86.0 0.573 G 63.9 10.7 86.0 0.573 0.0 HOH
 2.694
 OD1
 O
ASP D:300 C:313 88.0 0.587 G 61.1 8.3 NA NA NA
5c1v 1 Q08209 99.42 0.0 X-RAY
 2016-02-03 ASP A:312 A:313 138.0 0.92 G 66.6 7.6 138.0 0.92 0.0
ASP B:312 B:313 22.0 0.147 E -103.6 146.0 NA NA NA
6uuq 1 Q08209 100.0 0.0 X-RAY
 2020-09-09 ASP A:290 A:313 112.0 NA S -76.4 -66.3 112.0 NA NA PO4
HOH
 8.910
4.016
 N
N
 O1
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q08209-f1 1 Q08209 100.0 0.0 ASP A:313 A:313 66.0 0.44 G 60.4 11.8
af-p16298-f1 1 P16298 85.63 0.0 ASP A:322 A:322 96.0 0.64 G 61.4 8.2
af-p48454-f1 1 P48454 81.84 0.0 ASP A:309 A:309 72.0 0.48 G 59.7 12.6