Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr4 | 102004359 | . | C | A | CCDS34037.1:NM_000944.4:c.844Gaa>Taa_NP_000935.1:p.282E>* | Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1aui | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
1997-12-03 | GLU | A:282 | A:282 | 32.0 | 0.168 | S | -117.2 | 128.4 | 32.0 | 0.168 | 0.0 |
ZN FE HOH |
5.531 5.477 2.463 |
N N OE1 |
ZN FE O |
||
| 4orb | 1 | P63328 | 97.7 | 0.0 |
X-RAY |
2015-05-20 | GLU | A:282 | A:282 | 30.0 | 0.158 | S | -135.3 | 117.9 | 30.0 | 0.158 | 0.0 |
ZN FE HOH |
5.329 5.165 6.690 |
N N N |
ZN FE O |
||
| 4il1 | 1 | P62161,P63100,P63329 | 97.76 | 0.0 |
X-RAY |
2013-10-02 | GLU | A:615 | A:615 | 32.0 | 0.168 | S | -116.4 | 130.3 | 32.0 | 0.168 | 0.0 |
HOH |
4.318 |
C |
O |
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| GLU | B:615 | B:615 | 38.0 | 0.2 | S | -94.1 | 130.0 | NA | NA | NA | |||||||||||||
| GLU | C:615 | C:615 | 32.0 | 0.168 | S | -113.3 | 130.6 | NA | NA | NA | |||||||||||||
| GLU | D:615 | D:615 | 41.0 | 0.216 | S | -111.7 | 131.5 | NA | NA | NA | |||||||||||||
| 4or9 | 1 | P16298 | 85.63 | 0.0 |
X-RAY |
2015-05-20 | GLU | A:311 | A:291 | 45.0 | 0.237 | S | -130.4 | 128.2 | 45.0 | 0.237 | 0.0 |
FE ZN HOH |
5.589 5.470 2.601 |
N N OE2 |
FE ZN O |
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| 4orc | 1 | P16298 | 85.63 | 0.0 |
X-RAY |
2015-05-20 | GLU | A:311 | A:291 | 47.0 | 0.247 | S | -120.4 | 120.8 | 47.0 | 0.247 | 0.0 |
ZN FE PO4 HOH |
5.625 5.338 5.413 3.845 |
N N N CA |
ZN FE O2 O |
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| 4ora | 1 | P16298 | 85.23 | 0.0 |
X-RAY |
2015-05-20 | GLU | A:311 | A:291 | 43.0 | 0.226 | S | -121.9 | 124.9 | 43.0 | 0.226 | 0.0 |
ZN FE HOH |
5.179 5.314 2.580 |
N N OE1 |
ZN FE O |
||
| 2p6b | 2 | Q08209 | 100.0 | 0.0 |
X-RAY |
2007-06-05 | GLU | B:285 | A:282 | 49.0 | 0.258 | S | -128.2 | 126.5 | 49.0 | 0.258 | 0.0 |
ZN FE PO4 HOH |
5.608 5.541 5.974 2.457 |
N N CA OE1 |
ZN FE O4 O |
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| GLU | D:285 | C:282 | 54.0 | 0.284 | S | -131.2 | 121.3 | 54.0 | 0.284 | 0.0 |
ZN FE PO4 HOH |
5.589 5.468 5.922 2.640 |
N N N OE1 |
ZN FE O4 O |
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| 1tco | 1 | P48452 | 99.73 | 0.0 |
X-RAY |
1997-02-12 | GLU | A:265 | A:282 | 51.0 | 0.268 | S | -130.2 | 117.0 | 51.0 | 0.268 | 0.0 |
ZN FE PO4 HOH |
5.584 5.494 6.305 2.681 |
N N N OE2 |
ZN FE O2 O |
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| 1mf8 | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | GLU | A:263 | A:282 | 45.0 | 0.237 | S | -105.3 | 138.4 | 45.0 | 0.237 | 0.0 |
PO4 |
5.137 |
CA |
O1 |
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| 1m63 | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2002-09-25 | GLU | A:282 | A:282 | 47.0 | 0.247 | S | -99.3 | 129.5 | 47.0 | 0.247 | 0.0 |
ZN FE |
5.492 5.521 |
N N |
ZN FE |
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| GLU | E:282 | E:282 | 43.0 | 0.226 | S | -94.3 | 144.0 | 43.0 | 0.226 | 0.0 |
ZN FE |
5.253 5.682 |
N N |
ZN FE |
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| 5sve | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | GLU | A:282 | A:282 | 51.0 | 0.268 | S | -127.3 | 128.4 | 51.0 | 0.268 | 0.0 |
FE ZN HOH |
5.855 5.731 2.974 |
N N OE2 |
FE ZN O |
||
| 4f0z | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2013-03-06 | GLU | A:284 | A:282 | 52.0 | 0.274 | S | -131.6 | 128.0 | 52.0 | 0.274 | 0.0 |
GOL HOH |
2.586 2.667 |
HA OE2 |
HO2 O |
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| 6nuc | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2019-07-03 | GLU | A:284 | A:282 | 50.0 | 0.263 | S | -127.8 | 124.5 | 50.0 | 0.263 | 0.0 |
FE ZN PO4 HOH |
5.789 5.799 5.079 2.551 |
N N HA OE2 |
FE ZN O2 O |
||
| 6nuf | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2019-07-03 | GLU | A:284 | A:282 | 51.0 | 0.268 | S | -126.4 | 122.3 | 51.0 | 0.268 | 0.0 |
FE ZN PO4 HOH |
5.880 5.883 5.170 2.584 |
N N HA OE2 |
FE ZN O2 O |
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| 6nuu | 1 | Q08209 | 99.46 | 0.0 |
X-RAY |
2019-07-03 | GLU | A:284 | A:282 | 50.0 | 0.263 | S | -124.0 | 122.3 | 50.0 | 0.263 | 0.0 |
FE ZN PO4 HOH |
5.762 5.748 5.057 2.476 |
N N HA OE2 |
FE ZN O2 O |
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| 3ll8 | 2 | Q08209 | 100.0 | 0.0 |
X-RAY |
2011-01-12 | GLU | B:269 | A:282 | 52.0 | 0.274 | S | -126.9 | 126.7 | 52.0 | 0.274 | 0.0 |
PO4 ZN FE HOH |
5.739 5.760 5.829 2.635 |
N N N OE1 |
O4 ZN FE O |
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| GLU | D:269 | C:282 | 51.0 | 0.268 | S | -126.3 | 124.4 | NA | NA | NA | |||||||||||||
| 5c1v | 1 | Q08209 | 99.42 | 0.0 |
X-RAY |
2016-02-03 | GLU | A:281 | A:282 | 42.0 | 0.221 | S | -83.9 | 126.6 | 42.0 | 0.221 | 0.0 |
FE ZN PO4 |
5.870 5.784 6.106 |
N N N |
FE ZN O4 |
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| GLU | B:281 | B:282 | 113.0 | 0.595 | -83.4 | 360.0 | NA | NA | NA | ||||||||||||||
| 6uuq | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2020-09-09 | GLU | A:259 | A:282 | 48.0 | 0.253 | S | -125.2 | 121.6 | 48.0 | 0.253 | 0.0 |
PO4 PO4 ZN FE HOH |
5.838 5.424 5.982 5.790 2.686 |
N N N N OE2 |
O4 O2 ZN FE O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q08209-f1 | 1 | Q08209 | 100.0 | 0.0 | GLU | A:282 | A:282 | 27.0 | 0.142 | S | -126.1 | 118.5 | |
| af-p16298-f1 | 1 | P16298 | 85.63 | 0.0 | GLU | A:291 | A:291 | 26.0 | 0.137 | S | -124.4 | 121.4 | |
| af-p48454-f1 | 1 | P48454 | 81.84 | 0.0 | GLU | A:278 | A:278 | 25.0 | 0.132 | S | -124.8 | 116.8 | |