Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 102004360 . G A CCDS34037.1:NM_000944.4:c.843caC>caT_NP_000935.1:p.281H>H Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1aui 1 Q08209 100.0 0.0 X-RAY
 1997-12-03 HIS A:281 A:281 0.0 0.0 75.6 -37.5 0.0 0.0 0.0 ZN
FE
HOH
 2.294
3.928
2.650
 ND1
O
O
 ZN
FE
O
4orb 1 P63328 97.7 0.0 X-RAY
 2015-05-20 HIS A:281 A:281 3.0 0.015 75.7 -12.1 3.0 0.015 0.0 ZN
FE
HOH
 2.518
3.980
4.241
 ND1
O
CE1
 ZN
FE
O
4il1 1 P62161,P63100,P63329 97.76 0.0 X-RAY
 2013-10-02 HIS A:614 A:614 4.0 0.021 -150.4 -19.3 4.0 0.021 0.0 HOH
 3.198
 O
 O
HIS B:614 B:614 12.0 0.062 -163.8 -37.1 NA NA NA
HIS C:614 C:614 3.0 0.015 -153.4 -18.1 NA NA NA
HIS D:614 D:614 3.0 0.015 -154.2 -19.4 NA NA NA
4or9 1 P16298 85.63 0.0 X-RAY
 2015-05-20 HIS A:310 A:290 3.0 0.015 76.8 -20.1 3.0 0.015 0.0 FE
ZN
HOH
 4.412
2.261
3.751
 O
ND1
O
 FE
ZN
O
4orc 1 P16298 85.63 0.0 X-RAY
 2015-05-20 HIS A:310 A:290 10.0 0.051 72.7 -34.6 10.0 0.051 0.0 ZN
FE
PO4
HOH
 2.416
3.801
3.212
3.705
 ND1
O
O
O
 ZN
FE
O2
O
4ora 1 P16298 85.23 0.0 X-RAY
 2015-05-20 HIS A:310 A:290 1.0 0.005 73.4 -27.2 1.0 0.005 0.0 ZN
FE
HOH
 2.617
3.571
3.196
 ND1
O
O
 ZN
FE
O
2p6b 2 Q08209 100.0 0.0 X-RAY
 2007-06-05 HIS B:284 A:281 9.0 0.046 S 69.9 -24.6 9.0 0.046 0.0 ZN
FE
PO4
HOH
 2.274
4.197
3.196
3.260
 ND1
O
CE1
O
 ZN
FE
O2
O
HIS D:284 C:281 8.0 0.041 S 72.8 -23.7 8.0 0.041 0.0 ZN
FE
PO4
HOH
 2.467
4.227
3.609
3.156
 ND1
O
CE1
O
 ZN
FE
O2
O
1tco 1 P48452 99.73 0.0 X-RAY
 1997-02-12 HIS A:264 A:281 9.0 0.046 75.6 -18.5 9.0 0.046 0.0 ZN
FE
PO4
HOH
 2.465
4.224
3.484
2.714
 ND1
O
ND1
O
 ZN
FE
O2
O
1mf8 1 Q08209 100.0 0.0 X-RAY
 2002-10-16 HIS A:262 A:281 9.0 0.046 S 80.0 -49.5 9.0 0.046 0.0 PO4
 4.564
 O
 O1
1m63 1 Q08209 100.0 0.0 X-RAY
 2002-09-25 HIS A:281 A:281 10.0 0.051 62.1 -47.4 10.0 0.051 0.0 ZN
FE
 2.244
3.582
 ND1
O
 ZN
FE
HIS E:281 E:281 7.0 0.036 71.7 -52.5 7.0 0.036 0.0 ZN
FE
 2.236
3.740
 ND1
O
 ZN
FE
5sve 1 Q08209 100.0 0.0 X-RAY
 2017-01-11 HIS A:281 A:281 9.0 0.046 S 68.9 -26.8 9.0 0.046 0.0 FE
ZN
HOH
 4.486
2.316
2.876
 O
ND1
O
 FE
ZN
O
4f0z 1 Q08209 100.0 0.0 X-RAY
 2013-03-06 HIS A:283 A:281 7.0 0.036 76.4 -16.6 7.0 0.036 0.0 GOL
HOH
 2.081
1.903
 O
HD1
 HO2
O
6nuc 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 HIS A:283 A:281 8.0 0.041 81.4 -21.4 8.0 0.041 0.0 FE
ZN
PO4
HOH
 3.778
2.221
2.669
2.394
 HA
ND1
HE1
HA
 FE
ZN
O1
O
6nuf 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 HIS A:283 A:281 8.0 0.041 78.6 -20.7 8.0 0.041 0.0 FE
ZN
PO4
PGE
HOH
 3.793
2.165
2.667
7.501
2.411
 HA
ND1
HE1
HE1
HA
 FE
ZN
O1
H3
O
6nuu 1 Q08209 99.46 0.0 X-RAY
 2019-07-03 HIS A:283 A:281 9.0 0.046 80.9 -25.9 9.0 0.046 0.0 FE
ZN
PO4
HOH
 3.798
2.183
2.461
2.342
 HA
ND1
HE1
HA
 FE
ZN
O1
O
3ll8 2 Q08209 100.0 0.0 X-RAY
 2011-01-12 HIS B:268 A:281 9.0 0.046 76.7 -21.6 9.0 0.046 0.0 PO4
ZN
FE
HOH
 3.219
2.216
4.567
4.424
 ND1
ND1
O
O
 O2
ZN
FE
O
HIS D:268 C:281 9.0 0.046 82.2 -22.6 NA NA NA
5c1v 1 Q08209 99.42 0.0 X-RAY
 2016-02-03 HIS A:280 A:281 10.0 0.051 S 80.6 -60.2 10.0 0.051 0.0 FE
ZN
PO4
 3.824
2.250
2.663
 O
ND1
ND1
 FE
ZN
O4
HIS B:280 B:281 17.0 0.087 82.6 -53.5 NA NA NA
6uuq 1 Q08209 100.0 0.0 X-RAY
 2020-09-09 HIS A:258 A:281 9.0 0.046 S 79.6 -26.5 9.0 0.046 0.0 PO4
PO4
ZN
FE
HOH
 3.191
4.202
4.524
2.216
2.750
 CE1
O
O
ND1
O
 O2
O2
ZN
FE
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q08209-f1 1 Q08209 100.0 0.0 HIS A:281 A:281 5.0 0.026 S 65.3 -15.0
af-p16298-f1 1 P16298 85.63 0.0 HIS A:290 A:290 3.0 0.015 62.0 -18.8
af-p48454-f1 1 P48454 81.84 0.0 HIS A:277 A:277 5.0 0.026 S 62.7 -16.0