Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 102014990 . T A CCDS34037.1:NM_000944.4:c.725gAg>gTg_NP_000935.1:p.242E>V Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA.
pdb_id: 
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label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1aui 1 Q08209 100.0 0.0 X-RAY
 1997-12-03 GLU A:242 A:242 24.0 0.126 -56.8 147.0 24.0 0.126 0.0 HOH
 2.620
 OE2
 O
4orb 1 P63328 97.7 0.0 X-RAY
 2015-05-20 GLU A:242 A:242 23.0 0.121 -74.3 148.7 23.0 0.121 0.0 HOH
 3.232
 CB
 O
4il1 1 P62161,P63100,P63329 97.76 0.0 X-RAY
 2013-10-02 GLU A:575 A:575 39.0 0.205 -80.0 135.3 39.0 0.205 0.0 HOH
 7.902
 CA
 O
GLU B:575 B:575 40.0 0.211 -66.4 137.7 NA NA NA
GLU C:575 C:575 45.0 0.237 -72.6 143.3 NA NA NA
GLU D:575 D:575 16.0 0.084 -96.6 86.3 NA NA NA
4or9 1 P16298 85.63 0.0 X-RAY
 2015-05-20 GLU A:271 A:251 37.0 0.195 -79.8 152.9 37.0 0.195 0.0 HOH
 7.407
 OE2
 O
4orc 1 P16298 85.63 0.0 X-RAY
 2015-05-20 GLU A:271 A:251 33.0 0.174 -73.5 143.2 33.0 0.174 0.0
4ora 1 P16298 85.23 0.0 X-RAY
 2015-05-20 GLU A:271 A:251 44.0 0.232 -74.8 136.3 44.0 0.232 0.0
2p6b 2 Q08209 100.0 0.0 X-RAY
 2007-06-05 GLU B:245 A:242 43.0 0.226 -71.4 146.6 43.0 0.226 0.0 HOH
 3.828
 CA
 O
GLU D:245 C:242 30.0 0.158 -97.7 139.6 30.0 0.158 0.0 HOH
 2.724
 O
 O
1tco 1 P48452 99.73 0.0 X-RAY
 1997-02-12 GLU A:225 A:242 40.0 0.211 -98.0 161.1 40.0 0.211 0.0 HOH
 3.126
 O
 O
1mf8 1 Q08209 100.0 0.0 X-RAY
 2002-10-16 GLU A:223 A:242 24.0 0.126 -61.4 142.1 24.0 0.126 0.0
1m63 1 Q08209 100.0 0.0 X-RAY
 2002-09-25 GLU A:242 A:242 45.0 0.237 -67.2 107.2 45.0 0.237 0.0
GLU E:242 E:242 39.0 0.205 -98.0 79.7 39.0 0.205 0.0
5sve 1 Q08209 100.0 0.0 X-RAY
 2017-01-11 GLU A:242 A:242 32.0 0.168 -68.5 160.8 32.0 0.168 0.0
4f0z 1 Q08209 100.0 0.0 X-RAY
 2013-03-06 GLU A:244 A:242 36.0 0.189 -64.9 145.8 36.0 0.189 0.0 GOL
HOH
 2.215
2.538
 HB3
HG2
 H12
O
6nuc 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 GLU A:244 A:242 44.0 0.232 -71.7 118.3 44.0 0.232 0.0 HOH
 3.496
 HG2
 O
6nuf 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 GLU A:244 A:242 47.0 0.247 -66.8 128.7 47.0 0.247 0.0 HOH
 3.861
 HG2
 O
6nuu 1 Q08209 99.46 0.0 X-RAY
 2019-07-03 GLU A:244 A:242 49.0 0.258 -81.6 111.2 49.0 0.258 0.0 HOH
 4.470
 HB3
 O
3ll8 2 Q08209 100.0 0.0 X-RAY
 2011-01-12 GLU B:229 A:242 43.0 0.226 -66.8 145.9 43.0 0.226 0.0 HOH
 4.178
 CA
 O
GLU D:229 C:242 34.0 0.179 -103.2 136.2 NA NA NA
5c1v 1 Q08209 99.42 0.0 X-RAY
 2016-02-03 GLU A:241 A:242 27.0 0.142 -57.7 148.8 27.0 0.142 0.0
GLU B:241 B:242 29.0 0.153 -58.3 150.5 NA NA NA
6uuq 1 Q08209 100.0 0.0 X-RAY
 2020-09-09 GLU A:219 A:242 39.0 0.205 -70.3 137.2 39.0 0.205 0.0 HOH
 2.885
 OE1
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q08209-f1 1 Q08209 100.0 0.0 GLU A:242 A:242 28.0 0.147 -60.0 143.6
af-p16298-f1 1 P16298 85.63 0.0 GLU A:251 A:251 23.0 0.121 -65.1 141.8
af-p48454-f1 1 P48454 81.84 0.0 GLU A:238 A:238 36.0 0.189 -60.8 141.4