Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr4 | 102015013 | . | G | A | CCDS34037.1:NM_000944.4:c.702gaC>gaT_NP_000935.1:p.234D>D | Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1aui | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
1997-12-03 | ASP | A:234 | A:234 | 0.0 | 0.0 | E | -134.1 | 155.0 | 0.0 | 0.0 | 0.0 |
ZN FE HOH |
7.238 8.854 3.970 |
OD1 OD1 CB |
ZN FE O |
||
| 4orb | 1 | P63328 | 97.7 | 0.0 |
X-RAY |
2015-05-20 | ASP | A:234 | A:234 | 1.0 | 0.007 | E | -123.7 | 160.3 | 1.0 | 0.007 | 0.0 |
ZN FE HOH |
7.176 8.004 7.423 |
OD1 OD1 OD1 |
ZN FE O |
||
| 4il1 | 1 | P62161,P63100,P63329 | 97.76 | 0.0 |
X-RAY |
2013-10-02 | ASP | A:567 | A:567 | 0.0 | 0.0 | E | -120.7 | 159.8 | 0.0 | 0.0 | 0.0 |
HOH |
7.599 |
OD1 |
O |
||
| ASP | B:567 | B:567 | 0.0 | 0.0 | E | -121.1 | 159.0 | NA | NA | NA | |||||||||||||
| ASP | C:567 | C:567 | 0.0 | 0.0 | E | -120.2 | 159.2 | NA | NA | NA | |||||||||||||
| ASP | D:567 | D:567 | 0.0 | 0.0 | E | -121.7 | 157.3 | NA | NA | NA | |||||||||||||
| 4or9 | 1 | P16298 | 85.63 | 0.0 |
X-RAY |
2015-05-20 | ASP | A:263 | A:243 | 0.0 | 0.0 | E | -132.1 | 154.2 | 0.0 | 0.0 | 0.0 |
FE ZN HOH |
8.760 6.917 4.131 |
OD1 OD1 CB |
FE ZN O |
||
| 4orc | 1 | P16298 | 85.63 | 0.0 |
X-RAY |
2015-05-20 | ASP | A:263 | A:243 | 0.0 | 0.0 | E | -128.3 | 163.1 | 0.0 | 0.0 | 0.0 |
ZN FE PO4 HOH |
7.053 8.473 6.707 7.221 |
OD1 OD1 OD1 OD1 |
ZN FE O2 O |
||
| 4ora | 1 | P16298 | 85.23 | 0.0 |
X-RAY |
2015-05-20 | ASP | A:263 | A:243 | 0.0 | 0.0 | E | -121.0 | 156.8 | 0.0 | 0.0 | 0.0 |
ZN FE HOH |
6.969 8.367 3.980 |
OD1 OD1 CB |
ZN FE O |
||
| 2p6b | 2 | Q08209 | 100.0 | 0.0 |
X-RAY |
2007-06-05 | ASP | B:237 | A:234 | 1.0 | 0.007 | E | -134.1 | 159.0 | 1.0 | 0.007 | 0.0 |
ZN FE PO4 HOH |
6.968 8.626 7.132 2.942 |
OD1 OD1 OD1 OD2 |
ZN FE O4 O |
||
| ASP | D:237 | C:234 | 1.0 | 0.007 | E | -133.4 | 156.0 | 1.0 | 0.007 | 0.0 |
ZN FE PO4 HOH |
7.047 8.640 7.042 2.849 |
OD1 OD1 OD1 OD2 |
ZN FE O4 O |
|||||||||
| 1tco | 1 | P48452 | 99.73 | 0.0 |
X-RAY |
1997-02-12 | ASP | A:217 | A:234 | 2.0 | 0.013 | E | -144.5 | 150.4 | 2.0 | 0.013 | 0.0 |
ZN FE PO4 HOH |
7.064 8.623 7.368 2.922 |
OD1 OD1 OD1 OD2 |
ZN FE O2 O |
||
| 1mf8 | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | ASP | A:215 | A:234 | 0.0 | 0.0 | E | -132.5 | 147.1 | 0.0 | 0.0 | 0.0 |
PO4 |
7.783 |
OD2 |
O4 |
||
| 1m63 | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2002-09-25 | ASP | A:234 | A:234 | 0.0 | 0.0 | E | -105.8 | 151.4 | 0.0 | 0.0 | 0.0 |
ZN FE |
6.957 8.327 |
OD1 OD1 |
ZN FE |
||
| ASP | E:234 | E:234 | 0.0 | 0.0 | E | -137.4 | 156.6 | 0.0 | 0.0 | 0.0 |
ZN FE |
6.960 8.866 |
OD1 OD1 |
ZN FE |
|||||||||
| 5sve | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:234 | A:234 | 1.0 | 0.007 | E | -125.2 | 156.1 | 1.0 | 0.007 | 0.0 |
FE ZN HOH |
8.986 7.025 2.699 |
OD1 OD1 OD2 |
FE ZN O |
||
| 4f0z | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2013-03-06 | ASP | A:236 | A:234 | 1.0 | 0.007 | E | -134.3 | 153.2 | 1.0 | 0.007 | 0.0 |
GOL GOL HOH |
5.670 9.354 2.830 |
OD2 O OD1 |
HO2 H11 O |
||
| 6nuc | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2019-07-03 | ASP | A:236 | A:234 | 0.0 | 0.0 | E | -131.0 | 156.4 | 0.0 | 0.0 | 0.0 |
FE ZN PO4 HOH |
8.931 7.124 6.997 2.803 |
OD1 OD1 OD1 OD2 |
FE ZN O2 O |
||
| 6nuf | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2019-07-03 | ASP | A:236 | A:234 | 1.0 | 0.007 | E | -131.1 | 152.7 | 1.0 | 0.007 | 0.0 |
FE ZN PO4 HOH |
8.972 7.144 6.979 2.762 |
OD1 OD1 OD1 OD2 |
FE ZN O2 O |
||
| 6nuu | 1 | Q08209 | 99.46 | 0.0 |
X-RAY |
2019-07-03 | ASP | A:236 | A:234 | 1.0 | 0.007 | E | -124.4 | 154.9 | 1.0 | 0.007 | 0.0 |
FE ZN PO4 HOH |
8.806 6.970 6.750 3.084 |
OD1 OD1 OD1 OD2 |
FE ZN O2 O |
||
| 3ll8 | 2 | Q08209 | 100.0 | 0.0 |
X-RAY |
2011-01-12 | ASP | B:221 | A:234 | 2.0 | 0.013 | E | -139.6 | 158.6 | 2.0 | 0.013 | 0.0 |
PO4 ZN FE HOH |
6.779 7.074 8.961 2.671 |
OD1 OD1 OD1 OD2 |
O4 ZN FE O |
||
| ASP | D:221 | C:234 | 1.0 | 0.007 | E | -139.0 | 154.0 | NA | NA | NA | |||||||||||||
| 5c1v | 1 | Q08209 | 99.42 | 0.0 |
X-RAY |
2016-02-03 | ASP | A:233 | A:234 | 1.0 | 0.007 | E | -130.6 | 155.5 | 1.0 | 0.007 | 0.0 |
FE ZN PO4 |
8.512 7.188 7.229 |
OD1 OD1 OD1 |
FE ZN O4 |
||
| ASP | B:233 | B:234 | 1.0 | 0.007 | E | -128.7 | 154.2 | NA | NA | NA | |||||||||||||
| 6uuq | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2020-09-09 | ASP | A:211 | A:234 | 0.0 | 0.0 | E | -132.9 | 154.0 | 0.0 | 0.0 | 0.0 |
PO4 PO4 ZN FE HOH |
6.999 8.431 9.079 7.158 2.898 |
OD1 OD1 OD1 OD1 OD2 |
O4 O3 ZN FE O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q08209-f1 | 1 | Q08209 | 100.0 | 0.0 | ASP | A:234 | A:234 | 2.0 | 0.013 | E | -128.0 | 153.3 | |
| af-p16298-f1 | 1 | P16298 | 85.63 | 0.0 | ASP | A:243 | A:243 | 2.0 | 0.013 | E | -128.4 | 154.2 | |
| af-p48454-f1 | 1 | P48454 | 81.84 | 0.0 | ASP | A:230 | A:230 | 2.0 | 0.013 | E | -127.0 | 154.0 | |