Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 102015044 . T A CCDS34037.1:NM_000944.4:c.671tAt>tTt_NP_000935.1:p.224Y>F Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA.
pdb_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1aui 1 Q08209 100.0 0.0 X-RAY
 1997-12-03 TYR A:224 A:224 203.0 0.883 S -141.0 154.7 203.0 0.883 0.0 HOH
 2.672
 OH
 O
4orb 1 P63328 97.7 0.0 X-RAY
 2015-05-20 TYR A:224 A:224 203.0 0.883 S -146.1 150.5 203.0 0.883 0.0 HOH
 4.639
 O
 O
4il1 1 P62161,P63100,P63329 97.76 0.0 X-RAY
 2013-10-02 TYR A:557 A:557 178.0 0.774 S -161.0 170.2 178.0 0.774 0.0 HOH
 6.711
 CB
 O
TYR B:557 B:557 181.0 0.787 S -161.0 170.7 NA NA NA
TYR C:557 C:557 172.0 0.748 S -162.6 170.5 NA NA NA
TYR D:557 D:557 184.0 0.8 S -162.1 171.3 NA NA NA
4or9 1 P16298 85.63 0.0 X-RAY
 2015-05-20 PHE A:253 A:233 157.0 0.748 S -159.7 165.8 157.0 0.748 0.0 HOH
 2.763
 O
 O
4orc 1 P16298 85.63 0.0 X-RAY
 2015-05-20 PHE A:253 A:233 162.0 0.771 S -157.8 177.1 162.0 0.771 0.0 HOH
 9.917
 N
 O
4ora 1 P16298 85.23 0.0 X-RAY
 2015-05-20 PHE A:253 A:233 159.0 0.757 S -153.1 163.9 159.0 0.757 0.0 HOH
 3.206
 CA
 O
2p6b 2 Q08209 100.0 0.0 X-RAY
 2007-06-05 TYR B:227 A:224 191.0 0.83 S -167.5 163.0 191.0 0.83 0.0 HOH
 2.676
 O
 O
TYR D:227 C:224 195.0 0.848 S -157.7 160.9 195.0 0.848 0.0 HOH
 2.610
 O
 O
1tco 1 P48452 99.73 0.0 X-RAY
 1997-02-12 TYR A:207 A:224 180.0 0.783 S -171.4 171.7 180.0 0.783 0.0 HOH
 2.725
 O
 O
1mf8 1 Q08209 100.0 0.0 X-RAY
 2002-10-16 TYR A:205 A:224 129.0 0.561 S -170.3 165.3 129.0 0.561 0.0
1m63 1 Q08209 100.0 0.0 X-RAY
 2002-09-25 TYR A:224 A:224 192.0 0.835 S -138.3 163.3 192.0 0.835 0.0
TYR E:224 E:224 180.0 0.783 S -146.7 -174.7 180.0 0.783 0.0
5sve 1 Q08209 100.0 0.0 X-RAY
 2017-01-11 TYR A:224 A:224 193.0 0.839 S -150.9 159.5 193.0 0.839 0.0 HOH
 2.782
 OH
 O
4f0z 1 Q08209 100.0 0.0 X-RAY
 2013-03-06 TYR A:226 A:224 198.0 0.861 S -146.9 155.0 198.0 0.861 0.0 HOH
 2.648
 O
 O
6nuc 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 TYR A:226 A:224 178.0 0.774 S -158.8 164.2 178.0 0.774 0.0 HOH
 2.548
 OH
 O
6nuf 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 TYR A:226 A:224 184.0 0.8 S -156.0 161.5 184.0 0.8 0.0 PGE
HOH
 5.342
1.856
 N
HH
 HO1
O
6nuu 1 Q08209 99.46 0.0 X-RAY
 2019-07-03 TYR A:226 A:224 176.0 0.765 S -150.2 167.8 176.0 0.765 0.0 HOH
 2.460
 HD2
 O
3ll8 2 Q08209 100.0 0.0 X-RAY
 2011-01-12 TYR B:211 A:224 193.0 0.839 S -159.8 170.2 193.0 0.839 0.0 HOH
 2.642
 O
 O
TYR D:211 C:224 195.0 0.848 S -156.9 165.0 NA NA NA
5c1v 1 Q08209 99.42 0.0 X-RAY
 2016-02-03 TYR A:223 A:224 166.0 0.722 S -140.3 161.4 166.0 0.722 0.0
TYR B:223 B:224 177.0 0.77 S -136.1 161.8 NA NA NA
6uuq 1 Q08209 100.0 0.0 X-RAY
 2020-09-09 TYR A:201 A:224 188.0 0.817 S -153.9 165.2 188.0 0.817 0.0 HOH
 2.456
 OH
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q08209-f1 1 Q08209 100.0 0.0 TYR A:224 A:224 185.0 0.804 S -155.2 168.6
af-p16298-f1 1 P16298 85.63 0.0 PHE A:233 A:233 159.0 0.757 S -143.5 162.9
af-p48454-f1 1 P48454 81.84 0.0 PHE A:220 A:220 165.0 0.786 S -154.9 167.4