Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr4 | 102020813 | . | G | A | CCDS34037.1:NM_000944.4:c.451Cat>Tat_NP_000935.1:p.151H>Y | Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 1aui | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
1997-12-03 | HIS | A:151 | A:151 | 1.0 | 0.005 | T | -82.1 | -10.1 | 1.0 | 0.005 | 0.0 |
ZN FE HOH |
4.387 4.358 2.707 |
CD2 CD2 NE2 |
ZN FE O |
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| 4orb | 1 | P63328 | 97.7 | 0.0 |
X-RAY |
2015-05-20 | HIS | A:151 | A:151 | 6.0 | 0.031 | T | -81.2 | -14.9 | 6.0 | 0.031 | 0.0 |
ZN FE HOH |
4.194 4.211 3.297 |
CD2 NE2 NE2 |
ZN FE O |
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| 4il1 | 1 | P62161,P63100,P63329 | 97.76 | 0.0 |
X-RAY |
2013-10-02 | HIS | A:484 | A:484 | 13.0 | 0.067 | T | -78.0 | -10.1 | 13.0 | 0.067 | 0.0 |
HOH |
4.017 |
CD2 |
O |
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| HIS | B:484 | B:484 | 12.0 | 0.062 | T | -77.5 | -11.1 | NA | NA | NA | |||||||||||||
| HIS | C:484 | C:484 | 12.0 | 0.062 | T | -76.1 | -12.1 | NA | NA | NA | |||||||||||||
| HIS | D:484 | D:484 | 8.0 | 0.041 | T | -79.6 | -9.9 | NA | NA | NA | |||||||||||||
| 4or9 | 1 | P16298 | 85.63 | 0.0 |
X-RAY |
2015-05-20 | HIS | A:180 | A:160 | 5.0 | 0.026 | T | -79.6 | -14.9 | 5.0 | 0.026 | 0.0 |
FE ZN HOH |
4.252 4.347 3.157 |
CD2 CD2 NE2 |
FE ZN O |
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| 4orc | 1 | P16298 | 85.63 | 0.0 |
X-RAY |
2015-05-20 | HIS | A:180 | A:160 | 8.0 | 0.041 | T | -77.1 | -15.4 | 8.0 | 0.041 | 0.0 |
ZN FE PO4 HOH |
4.278 4.553 2.748 6.767 |
CD2 CD2 NE2 O |
ZN FE O1 O |
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| 4ora | 1 | P16298 | 85.23 | 0.0 |
X-RAY |
2015-05-20 | HIS | A:180 | A:160 | 3.0 | 0.015 | T | -81.4 | -14.1 | 3.0 | 0.015 | 0.0 |
ZN FE HOH |
4.162 4.523 6.712 |
CD2 NE2 NE2 |
ZN FE O |
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| 2p6b | 2 | Q08209 | 100.0 | 0.0 |
X-RAY |
2007-06-05 | HIS | B:154 | A:151 | 4.0 | 0.021 | T | -78.5 | -15.0 | 4.0 | 0.021 | 0.0 |
ZN FE PO4 HOH |
4.383 4.395 2.650 4.862 |
CD2 CD2 NE2 NE2 |
ZN FE O3 O |
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| HIS | D:154 | C:151 | 5.0 | 0.026 | T | -82.1 | -14.1 | 5.0 | 0.026 | 0.0 |
ZN FE PO4 HOH |
4.413 4.624 2.717 5.127 |
CD2 CD2 NE2 N |
ZN FE O3 O |
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| 1tco | 1 | P48452 | 99.73 | 0.0 |
X-RAY |
1997-02-12 | HIS | A:134 | A:151 | 4.0 | 0.021 | T | -87.0 | -18.1 | 4.0 | 0.021 | 0.0 |
ZN FE PO4 HOH |
4.397 4.397 2.657 4.475 |
CD2 CD2 NE2 NE2 |
ZN FE O1 O |
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| 1mf8 | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2002-10-16 | HIS | A:132 | A:151 | 18.0 | 0.092 | T | -81.2 | 2.5 | 18.0 | 0.092 | 0.0 |
PO4 |
5.169 |
NE2 |
O3 |
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| 1m63 | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2002-09-25 | HIS | A:151 | A:151 | 2.0 | 0.01 | T | -89.3 | -8.2 | 2.0 | 0.01 | 0.0 |
ZN FE |
4.298 4.460 |
CD2 CD2 |
ZN FE |
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| HIS | E:151 | E:151 | 7.0 | 0.036 | T | -93.1 | -0.1 | 7.0 | 0.036 | 0.0 |
ZN FE |
4.393 4.315 |
CD2 CD2 |
ZN FE |
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| 5sve | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | HIS | A:151 | A:151 | 5.0 | 0.026 | T | -89.1 | -14.5 | 5.0 | 0.026 | 0.0 |
FE ZN HOH |
4.219 4.301 2.670 |
CD2 CD2 NE2 |
FE ZN O |
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| 4f0z | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2013-03-06 | HIS | A:153 | A:151 | 14.0 | 0.072 | T | -80.8 | -13.6 | 14.0 | 0.072 | 0.0 |
GOL GOL HOH |
4.334 8.900 2.245 |
HE2 HE1 HE2 |
H2 H12 O |
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| 6nuc | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2019-07-03 | HIS | A:153 | A:151 | 4.0 | 0.021 | T | -82.3 | -8.7 | 4.0 | 0.021 | 0.0 |
FE ZN PO4 HOH |
4.002 3.535 1.802 4.266 |
HD2 HD2 HE2 HD2 |
FE ZN O3 O |
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| 6nuf | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2019-07-03 | HIS | A:153 | A:151 | 4.0 | 0.021 | T | -83.8 | -10.8 | 4.0 | 0.021 | 0.0 |
FE ZN PO4 PGE HOH |
3.961 3.516 1.786 6.931 3.583 |
HD2 HD2 HE2 HE1 HE2 |
FE ZN O3 H5 O |
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| 6nuu | 1 | Q08209 | 99.46 | 0.0 |
X-RAY |
2019-07-03 | HIS | A:153 | A:151 | 3.0 | 0.015 | T | -84.8 | -20.7 | 3.0 | 0.015 | 0.0 |
FE ZN PO4 HOH |
3.966 3.508 2.810 4.492 |
HD2 HD2 NE2 HD2 |
FE ZN O3 O |
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| 3ll8 | 2 | Q08209 | 100.0 | 0.0 |
X-RAY |
2011-01-12 | HIS | B:138 | A:151 | 3.0 | 0.015 | T | -76.5 | -14.8 | 3.0 | 0.015 | 0.0 |
PO4 ZN FE HOH |
2.665 4.462 4.507 4.963 |
NE2 CD2 CD2 N |
O3 ZN FE O |
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| HIS | D:138 | C:151 | 3.0 | 0.015 | T | -75.4 | -16.3 | NA | NA | NA | |||||||||||||
| 5c1v | 1 | Q08209 | 99.42 | 0.0 |
X-RAY |
2016-02-03 | HIS | A:150 | A:151 | 2.0 | 0.01 | T | -79.4 | -12.3 | 2.0 | 0.01 | 0.0 |
FE ZN PO4 |
4.632 4.604 2.333 |
CD2 CD2 NE2 |
FE ZN O1 |
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| HIS | B:150 | B:151 | 3.0 | 0.015 | T | -77.6 | -13.2 | NA | NA | NA | |||||||||||||
| 6uuq | 1 | Q08209 | 100.0 | 0.0 |
X-RAY |
2020-09-09 | HIS | A:128 | A:151 | 5.0 | 0.026 | T | -78.1 | -13.4 | 5.0 | 0.026 | 0.0 |
PO4 PO4 ZN FE HOH |
2.694 5.190 4.415 4.439 4.043 |
NE2 NE2 CD2 CD2 NE2 |
O3 O4 ZN FE O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-q08209-f1 | 1 | Q08209 | 100.0 | 0.0 | HIS | A:151 | A:151 | 11.0 | 0.056 | T | -71.3 | -10.0 | |
| af-p16298-f1 | 1 | P16298 | 85.63 | 0.0 | HIS | A:160 | A:160 | 7.0 | 0.036 | S | -74.9 | -16.4 | |
| af-p48454-f1 | 1 | P48454 | 81.84 | 0.0 | HIS | A:147 | A:147 | 12.0 | 0.062 | T | -80.3 | -8.6 | |