Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 102020840 . T A CCDS34037.1:NM_000944.4:c.424Aaa>Taa_NP_000935.1:p.142K>* Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA.
pdb_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1aui 1 Q08209 100.0 0.0 X-RAY
 1997-12-03 LYS A:142 A:142 156.0 0.78 T -114.7 9.2 156.0 0.78 0.0 HOH
 2.494
 O
 O
4orb 1 P63328 97.7 0.0 X-RAY
 2015-05-20 LYS A:142 A:142 152.0 0.76 T -111.7 6.8 152.0 0.76 0.0 HOH
 3.031
 N
 O
4il1 1 P62161,P63100,P63329 97.76 0.0 X-RAY
 2013-10-02 LYS A:475 A:475 180.0 0.9 T -96.0 -7.9 180.0 0.9 0.0 HOH
 4.595
 O
 O
LYS B:475 B:475 182.0 0.91 T -97.1 -7.7 NA NA NA
LYS C:475 C:475 178.0 0.89 T -92.1 -11.8 NA NA NA
LYS D:475 D:475 185.0 0.925 T -93.6 -11.2 NA NA NA
4or9 1 P16298 85.63 0.0 X-RAY
 2015-05-20 SER A:171 A:151 88.0 0.765 T -102.4 5.5 88.0 0.765 0.0 HOH
 2.737
 N
 O
4orc 1 P16298 85.63 0.0 X-RAY
 2015-05-20 SER A:171 A:151 86.0 0.748 T -101.1 3.7 86.0 0.748 0.0 HOH
 2.785
 OG
 O
4ora 1 P16298 85.23 0.0 X-RAY
 2015-05-20 SER A:171 A:151 88.0 0.765 T -109.3 11.3 88.0 0.765 0.0 HOH
 5.211
 N
 O
2p6b 2 Q08209 100.0 0.0 X-RAY
 2007-06-05 LYS B:145 A:142 147.0 0.735 T -101.6 3.2 147.0 0.735 0.0 HOH
 3.017
 N
 O
LYS D:145 C:142 157.0 0.785 T -104.1 2.2 157.0 0.785 0.0 HOH
 2.645
 O
 O
1tco 1 P48452 99.73 0.0 X-RAY
 1997-02-12 LYS A:125 A:142 165.0 0.825 T -113.5 4.3 165.0 0.825 0.0 HOH
 2.785
 NZ
 O
1mf8 1 Q08209 100.0 0.0 X-RAY
 2002-10-16 LYS A:123 A:142 183.0 0.915 T -101.0 5.6 183.0 0.915 0.0
1m63 1 Q08209 100.0 0.0 X-RAY
 2002-09-25 LYS A:142 A:142 143.0 0.715 T -116.8 12.0 143.0 0.715 0.0
LYS E:142 E:142 138.0 0.69 T -100.2 15.8 138.0 0.69 0.0
5sve 1 Q08209 100.0 0.0 X-RAY
 2017-01-11 LYS A:142 A:142 159.0 0.795 T -113.4 1.9 159.0 0.795 0.0 HOH
 6.145
 C
 O
4f0z 1 Q08209 100.0 0.0 X-RAY
 2013-03-06 LYS A:144 A:142 170.0 0.85 T -101.2 1.0 170.0 0.85 0.0 HOH
 2.087
 H
 O
6nuc 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 LYS A:144 A:142 148.0 0.74 T -114.2 10.0 148.0 0.74 0.0 PEG
HOH
 5.923
2.061
 H
HZ2
 H41
O
6nuf 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 LYS A:144 A:142 148.0 0.74 T -109.5 5.3 148.0 0.74 0.0 PGE
HOH
 3.446
1.998
 HB2
HZ3
 H6
O
6nuu 1 Q08209 99.46 0.0 X-RAY
 2019-07-03 LYS A:144 A:142 158.0 0.79 T -113.6 16.9 158.0 0.79 0.0 PEG
HOH
 5.587
1.986
 H
H
 H41
O
3ll8 2 Q08209 100.0 0.0 X-RAY
 2011-01-12 LYS B:129 A:142 146.0 0.73 T -102.7 -4.5 146.0 0.73 0.0 HOH
 2.925
 NZ
 O
LYS D:129 C:142 152.0 0.76 T -106.9 -0.3 NA NA NA
5c1v 1 Q08209 99.42 0.0 X-RAY
 2016-02-03 LYS A:141 A:142 170.0 0.85 T -110.8 -19.2 170.0 0.85 0.0
LYS B:141 B:142 171.0 0.855 T -112.6 -19.6 NA NA NA
6uuq 1 Q08209 100.0 0.0 X-RAY
 2020-09-09 LYS A:119 A:142 165.0 0.825 T -104.7 -0.0 165.0 0.825 0.0 HOH
 2.566
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q08209-f1 1 Q08209 100.0 0.0 LYS A:142 A:142 179.0 0.895 T -98.5 -3.1
af-p16298-f1 1 P16298 85.63 0.0 SER A:151 A:151 87.0 0.757 T -101.0 -1.9
af-p48454-f1 1 P48454 81.84 0.0 LYS A:138 A:138 176.0 0.88 T -99.1 -3.2