Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 102030220 . T A CCDS34037.1:NM_000944.4:c.275cAt>cTt_NP_000935.1:p.92H>L Homo sapiens protein phosphatase 3 catalytic subunit alpha (PPP3CA), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1aui 1 Q08209 100.0 0.0 X-RAY
 1997-12-03 HIS A:92 A:92 0.0 0.0 T 57.9 53.1 0.0 0.0 0.0 ZN
FE
HOH
 5.146
2.367
2.988
 NE2
NE2
O
 ZN
FE
O
4orb 1 P63328 97.7 0.0 X-RAY
 2015-05-20 HIS A:92 A:92 3.0 0.015 T 50.7 57.0 3.0 0.015 0.0 ZN
FE
HOH
 4.544
2.967
4.998
 NE2
NE2
NE2
 ZN
FE
O
4il1 1 P62161,P63100,P63329 97.76 0.0 X-RAY
 2013-10-02 HIS A:425 A:425 4.0 0.021 T 55.0 52.8 4.0 0.021 0.0 HOH
 3.433
 CE1
 O
HIS B:425 B:425 4.0 0.021 T 55.0 52.7 NA NA NA
HIS C:425 C:425 3.0 0.015 T 56.1 51.9 NA NA NA
HIS D:425 D:425 4.0 0.021 T 57.5 51.4 NA NA NA
4or9 1 P16298 85.63 0.0 X-RAY
 2015-05-20 HIS A:121 A:101 1.0 0.005 T 51.3 47.9 1.0 0.005 0.0 FE
ZN
HOH
 2.155
5.040
3.211
 NE2
NE2
O
 FE
ZN
O
4orc 1 P16298 85.63 0.0 X-RAY
 2015-05-20 HIS A:121 A:101 3.0 0.015 T 50.6 50.9 3.0 0.015 0.0 ZN
FE
PO4
HOH
 4.869
2.434
3.297
5.651
 NE2
NE2
NE2
O
 ZN
FE
O1
O
4ora 1 P16298 85.23 0.0 X-RAY
 2015-05-20 HIS A:121 A:101 1.0 0.005 T 60.5 42.5 1.0 0.005 0.0 ZN
FE
HOH
 4.397
2.697
4.865
 NE2
NE2
NE2
 ZN
FE
O
2p6b 2 Q08209 100.0 0.0 X-RAY
 2007-06-05 HIS B:95 A:92 1.0 0.005 T 44.2 59.6 1.0 0.005 0.0 ZN
FE
PO4
HOH
 4.982
2.320
3.027
2.977
 NE2
NE2
NE2
O
 ZN
FE
O1
O
HIS D:95 C:92 0.0 0.0 T 48.2 55.6 0.0 0.0 0.0 ZN
FE
PO4
HOH
 5.039
2.363
3.172
2.824
 NE2
NE2
NE2
O
 ZN
FE
O1
O
1tco 1 P48452 99.73 0.0 X-RAY
 1997-02-12 HIS A:75 A:92 1.0 0.005 T 49.0 52.5 1.0 0.005 0.0 ZN
FE
PO4
HOH
 4.793
2.355
3.301
3.218
 NE2
NE2
NE2
O
 ZN
FE
O1
O
1mf8 1 Q08209 100.0 0.0 X-RAY
 2002-10-16 HIS A:73 A:92 5.0 0.026 T 38.5 55.1 5.0 0.026 0.0 PO4
 4.620
 CE1
 O3
1m63 1 Q08209 100.0 0.0 X-RAY
 2002-09-25 HIS A:92 A:92 1.0 0.005 T 49.2 45.0 1.0 0.005 0.0 ZN
FE
 4.736
2.260
 NE2
NE2
 ZN
FE
HIS E:92 E:92 2.0 0.01 T 31.3 62.1 2.0 0.01 0.0 ZN
FE
 5.037
2.251
 NE2
NE2
 ZN
FE
5sve 1 Q08209 100.0 0.0 X-RAY
 2017-01-11 HIS A:92 A:92 2.0 0.01 T 48.1 54.7 2.0 0.01 0.0 FE
ZN
HOH
 1.997
5.214
2.863
 NE2
CE1
NE2
 FE
ZN
O
4f0z 1 Q08209 100.0 0.0 X-RAY
 2013-03-06 HIS A:94 A:92 4.0 0.021 T 45.8 51.9 4.0 0.021 0.0 GOL
GOL
HOH
 1.888
9.117
2.832
 HE2
HB3
HB3
 HO1
HO1
O
6nuc 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 HIS A:94 A:92 1.0 0.005 T 47.8 52.8 1.0 0.005 0.0 FE
ZN
PO4
HOH
 2.107
4.992
2.921
2.815
 NE2
HE1
NE2
HB3
 FE
ZN
O4
O
6nuf 1 Q08209 100.0 0.0 X-RAY
 2019-07-03 HIS A:94 A:92 0.0 0.0 T 49.2 52.4 0.0 0.0 0.0 FE
ZN
PO4
HOH
 2.146
5.065
3.028
2.848
 NE2
HE1
NE2
HB3
 FE
ZN
O4
O
6nuu 1 Q08209 99.46 0.0 X-RAY
 2019-07-03 HIS A:94 A:92 1.0 0.005 T 40.8 58.3 1.0 0.005 0.0 FE
ZN
PO4
HOH
 2.122
4.892
3.071
3.087
 NE2
HE1
NE2
NE2
 FE
ZN
O4
O
3ll8 2 Q08209 100.0 0.0 X-RAY
 2011-01-12 HIS B:79 A:92 2.0 0.01 T 45.6 53.1 2.0 0.01 0.0 PO4
ZN
FE
HOH
 2.993
5.015
2.154
3.056
 NE2
NE2
NE2
O
 O1
ZN
FE
O
HIS D:79 C:92 1.0 0.005 T 45.1 52.3 NA NA NA
5c1v 1 Q08209 99.42 0.0 X-RAY
 2016-02-03 HIS A:91 A:92 2.0 0.01 T 55.2 57.1 2.0 0.01 0.0 FE
ZN
PO4
 2.483
5.085
2.806
 NE2
NE2
NE2
 FE
ZN
O3
HIS B:91 B:92 31.0 0.159 T 53.1 58.7 NA NA NA
6uuq 1 Q08209 100.0 0.0 X-RAY
 2020-09-09 HIS A:69 A:92 9.0 0.046 T 51.3 51.2 9.0 0.046 0.0 PO4
PO4
ZN
FE
HOH
 2.986
3.142
2.083
5.009
3.733
 NE2
NE2
NE2
NE2
CD2
 O1
O2
ZN
FE
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q08209-f1 1 Q08209 100.0 0.0 HIS A:92 A:92 6.0 0.031 T 47.6 49.0
af-p16298-f1 1 P16298 85.63 0.0 HIS A:101 A:101 4.0 0.021 T 46.9 51.3
af-p48454-f1 1 P48454 81.84 0.0 HIS A:88 A:88 5.0 0.026 T 47.5 49.9