Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 140432950 . C A CCDS3748.1:NM_030648.2:c.968aGa>aTa_NP_085151.1:p.323R>I Homo sapiens SET domain containing (lysine methyltransferase) 7 (SETD7), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1n6c 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-04 ARG A:254 A:323 113.0 0.502 S -159.1 176.2 113.0 0.502 0.0 HOH
 2.996
 NH2
 O
1h3i 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-11 ARG A:272 A:323 123.0 0.547 S -139.1 -177.6 123.0 0.547 0.0 HOH
 8.645
 NH2
 O
ARG B:272 B:323 152.0 0.676 S -140.3 176.9 NA NA NA
1mt6 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-06 ARG A:266 A:323 111.0 0.493 S -133.1 175.7 111.0 0.493 0.0 HOH
 3.385
 CB
 O
1n6a 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-04 ARG A:216 A:323 124.0 0.551 S -159.0 -168.9 124.0 0.551 0.0 HOH
 2.939
 NH2
 O
1o9s 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-06 ARG A:216 A:323 109.0 0.484 S -149.4 178.2 109.0 0.484 0.0 HOH
 2.431
 NE
 O
ARG B:216 B:323 104.0 0.462 S -155.8 176.9 NA NA NA
1xqh 1 Q8WTS6 100.0 0.0 X-RAY
 2004-11-23 ARG A:221 A:323 132.0 0.587 S -156.4 175.3 132.0 0.587 0.0 HOH
 2.920
 NH2
 O
ARG C:221 E:323 129.0 0.573 S -156.2 175.2 NA NA NA
4e47 1 Q8WTS6 100.0 0.0 X-RAY
 2012-03-28 ARG A:215 A:323 107.0 0.476 S -146.1 178.4 107.0 0.476 0.0 HOH
 2.905
 NH2
 O
ARG B:215 B:323 108.0 0.48 S -148.7 173.3 NA NA NA
ARG C:215 C:323 109.0 0.484 S -146.0 176.2 NA NA NA
ARG D:215 D:323 106.0 0.471 S -147.1 178.4 NA NA NA
4jds 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 ARG A:215 A:323 106.0 0.471 S -152.5 173.5 39.0 0.173 0.298 A:Q8WTS6:0.298
 UNX
UNX
UNX
HOH
 7.170
6.654
3.793
2.842
 C
C
NH2
NH1
 UNK
UNK
UNK
O
ARG B:215 B:323 104.0 0.462 S -148.0 172.2 NA NA NA
ARG C:215 C:323 107.0 0.476 S -148.4 172.1 NA NA NA
ARG D:215 D:323 104.0 0.462 S -145.8 170.3 NA NA NA
4jlg 1 Q8WTS6 100.0 0.0 X-RAY
 2013-04-17 ARG A:215 A:323 115.0 0.511 S -145.2 177.4 115.0 0.511 0.0 HOH
 2.821
 NH1
 O
ARG B:215 B:323 115.0 0.511 S -142.8 177.2 NA NA NA
2f69 1 Q8WTS6 100.0 0.0 X-RAY
 2006-01-17 ARG A:218 A:323 115.0 0.511 S -152.5 173.0 115.0 0.511 0.0 HOH
 2.773
 NE
 O
3m53 1 Q8WTS6 100.0 0.0 X-RAY
 2010-07-28 ARG A:218 A:323 109.0 0.484 S -147.8 170.9 109.0 0.484 0.0 HOH
 2.623
 NE
 O
4j83 1 Q8WTS6 100.0 0.0 X-RAY
 2014-01-08 ARG A:218 A:323 112.0 0.498 S -146.7 169.5 112.0 0.498 0.0 HOH
 2.766
 NE
 O
4j8o 1 Q8WTS6 100.0 0.0 X-RAY
 2014-01-08 ARG A:218 A:323 106.0 0.471 S -150.9 167.9 106.0 0.471 0.0 HOH
 2.656
 NE
 O
5eg2 1 Q8WTS6 99.23 0.0 X-RAY
 2016-01-13 ARG A:219 A:323 108.0 0.48 S -144.8 171.1 108.0 0.48 0.0 HOH
 2.734
 NE
 O
3m54 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:218 A:323 108.0 0.48 S -141.3 172.1 108.0 0.48 0.0 HOH
 2.725
 NE
 O
3m55 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:218 A:323 104.0 0.462 S -143.8 169.7 104.0 0.462 0.0 HOH
 3.435
 NH1
 O
3m56 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:218 A:323 110.0 0.489 S -149.6 172.1 110.0 0.489 0.0 HOH
 3.195
 CD
 O
4j7i 1 Q8WTS6 99.61 0.0 X-RAY
 2014-01-08 ARG A:218 A:323 51.0 NA S -137.1 159.0 51.0 NA NA
3vuz 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 ARG A:220 A:323 123.0 0.547 S -163.7 -175.9 123.0 0.547 0.0 HOH
 3.491
 NH2
 O
3vv0 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 ARG A:220 A:323 123.0 0.547 S -162.9 -176.0 123.0 0.547 0.0 HOH
 2.542
 NH1
 O
5ylt 1 Q8WTS6 100.0 0.0 X-RAY
 2018-06-20 ARG A:220 A:323 111.0 0.493 S -141.1 169.4 111.0 0.493 0.0 HOH
 2.808
 NE
 O
3cbm 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 ARG A:213 A:323 126.0 0.56 S -158.6 -169.8 126.0 0.56 0.0 HOH
 2.937
 NH1
 O
3cbo 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 ARG A:213 A:323 126.0 0.56 S -158.1 -167.6 126.0 0.56 0.0 HOH
 2.936
 NH1
 O
3cbp 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 ARG A:213 A:323 125.0 0.556 S -159.3 -166.9 125.0 0.556 0.0 GOL
HOH
 2.619
4.042
 NH1
CG
 O3
O
3os5 1 Q8WTS6 100.0 0.0 X-RAY
 2010-12-15 ARG A:213 A:323 126.0 0.56 S -159.8 -167.9 126.0 0.56 0.0 EDO
HOH
 2.713
2.773
 NH1
NH2
 O1
O
4j7f 1 Q8WTS6 99.61 0.0 X-RAY
 2014-03-26 ARG A:218 A:323 111.0 0.493 S -150.6 170.5 111.0 0.493 0.0 HOH
 2.844
 NE
 O
3m57 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:218 A:323 113.0 0.502 S -149.3 171.5 113.0 0.502 0.0 HOH
 2.755
 NE
 O
3m58 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:218 A:323 117.0 0.52 S -152.2 170.0 117.0 0.52 0.0 HOH
 3.106
 NH2
 O
3m59 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:218 A:323 116.0 0.516 S -149.4 173.1 116.0 0.516 0.0 HOH
 2.760
 NE
 O
3m5a 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:218 A:323 115.0 0.511 S -144.5 174.8 115.0 0.511 0.0 HOH
 6.940
 C
 O
1muf 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-06 ARG A:243 A:323 114.0 0.507 S -159.1 173.8 114.0 0.507 0.0 HOH
 3.100
 NE
 O
5ayf 1 Q8WTS6 94.92 0.0 X-RAY
 2016-04-27 ARG A:220 A:323 126.0 0.56 S -160.2 173.6 126.0 0.56 0.0 HOH
 2.570
 NH2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8wts6-f1 1 Q8WTS6 100.0 0.0 ARG A:323 A:323 112.0 0.498 S -142.4 176.2