Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 140439109 . C A CCDS3748.1:NM_030648.2:c.850Gta>Tta_NP_085151.1:p.284V>L Homo sapiens SET domain containing (lysine methyltransferase) 7 (SETD7), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1n6c 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-04 VAL A:215 A:284 47.0 0.303 T -57.9 -26.2 47.0 0.303 0.0 SAM
HOH
 7.160
2.748
 CG2
N
 OXT
O
1h3i 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-11 VAL A:233 A:284 53.0 0.342 T -57.4 -30.5 53.0 0.342 0.0 HOH
 3.341
 N
 O
VAL B:233 B:284 50.0 0.323 T -64.6 -22.7 NA NA NA
1mt6 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-06 VAL A:227 A:284 53.0 0.342 T -75.1 -14.3 53.0 0.342 0.0 SAH
HOH
 7.198
2.926
 CG1
N
 OXT
O
1n6a 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-04 VAL A:177 A:284 50.0 0.323 T -58.7 -25.1 50.0 0.323 0.0 SAM
HOH
 7.426
2.683
 CG2
O
 OXT
O
1o9s 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-06 VAL A:177 A:284 53.0 0.342 T -62.4 -23.5 53.0 0.342 0.0 SAH
HOH
 8.464
2.747
 CG2
O
 O
O
VAL B:177 B:284 57.0 0.368 T -61.2 -21.6 NA NA NA
1xqh 1 Q8WTS6 100.0 0.0 X-RAY
 2004-11-23 VAL A:182 A:284 47.0 0.303 T -59.1 -28.0 47.0 0.303 0.0 SAH
HOH
 7.324
2.912
 CG2
N
 O
O
VAL C:182 E:284 50.0 0.323 T -57.6 -29.3 NA NA NA
4e47 1 Q8WTS6 100.0 0.0 X-RAY
 2012-03-28 VAL A:176 A:284 54.0 0.348 T -62.9 -22.4 54.0 0.348 0.0 SAM
HOH
 7.541
2.689
 CG1
O
 O
O
VAL B:176 B:284 54.0 0.348 T -65.4 -23.4 NA NA NA
VAL C:176 C:284 54.0 0.348 T -61.1 -23.7 NA NA NA
VAL D:176 D:284 51.0 0.329 T -63.8 -22.3 NA NA NA
4jds 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 VAL A:176 A:284 53.0 0.342 T -63.5 -20.1 53.0 0.342 0.0 SAM
UNX
UNX
HOH
 7.606
3.337
4.032
2.531
 N
CG2
CG2
O
 OXT
UNK
UNK
O
VAL B:176 B:284 53.0 0.342 T -61.7 -24.3 NA NA NA
VAL C:176 C:284 49.0 0.316 T -60.0 -28.7 NA NA NA
VAL D:176 D:284 51.0 0.329 T -60.2 -29.2 NA NA NA
4jlg 1 Q8WTS6 100.0 0.0 X-RAY
 2013-04-17 VAL A:176 A:284 49.0 0.316 T -57.6 -25.6 49.0 0.316 0.0 SAM
UNX
UNX
HOH
 7.614
7.155
9.293
2.639
 CG2
N
O
O
 OXT
UNK
UNK
O
VAL B:176 B:284 51.0 0.329 T -66.9 -20.5 NA NA NA
2f69 1 Q8WTS6 100.0 0.0 X-RAY
 2006-01-17 VAL A:179 A:284 53.0 0.342 T -60.6 -27.8 53.0 0.342 0.0 SAH
HOH
 7.511
2.708
 CG2
O
 O
O
3m53 1 Q8WTS6 100.0 0.0 X-RAY
 2010-07-28 VAL A:179 A:284 53.0 0.342 T -67.4 -20.5 53.0 0.342 0.0 SAH
HOH
 7.472
2.661
 CG1
O
 O
O
4j83 1 Q8WTS6 100.0 0.0 X-RAY
 2014-01-08 VAL A:179 A:284 54.0 0.348 T -58.9 -25.9 54.0 0.348 0.0 SAM
HOH
 7.520
2.930
 CG2
O
 OXT
O
4j8o 1 Q8WTS6 100.0 0.0 X-RAY
 2014-01-08 VAL A:179 A:284 48.0 0.31 T -67.1 -16.2 48.0 0.31 0.0 SAH
HOH
 7.230
2.634
 CG1
O
 O
O
5eg2 1 Q8WTS6 99.23 0.0 X-RAY
 2016-01-13 VAL A:180 A:284 55.0 0.355 T -67.7 -16.8 55.0 0.355 0.0 SAH
HOH
 7.411
2.624
 CG1
O
 OXT
O
3m54 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 VAL A:179 A:284 54.0 0.348 T -64.7 -19.2 54.0 0.348 0.0 SAH
HOH
 7.477
2.708
 CG1
O
 O
O
3m55 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 VAL A:179 A:284 49.0 0.316 T -60.2 -24.2 49.0 0.316 0.0 HOH
 2.737
 O
 O
3m56 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 VAL A:179 A:284 49.0 0.316 T -63.6 -21.9 49.0 0.316 0.0 HOH
 2.576
 O
 O
4j7i 1 Q8WTS6 99.61 0.0 X-RAY
 2014-01-08 VAL A:179 A:284 53.0 0.342 T -70.8 -22.3 53.0 0.342 0.0 SAH
HOH
 7.817
3.677
 CG1
N
 O
O
3vuz 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 VAL A:181 A:284 51.0 0.329 T -59.0 -28.5 51.0 0.329 0.0 K15
HOH
 7.635
2.752
 CG2
N
 O
O
3vv0 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 VAL A:181 A:284 52.0 0.335 T -62.1 -28.1 52.0 0.335 0.0 KH3
HOH
 7.507
2.650
 CG2
N
 OXT
O
5ylt 1 Q8WTS6 100.0 0.0 X-RAY
 2018-06-20 VAL A:181 A:284 51.0 0.329 T -64.3 -23.4 51.0 0.329 0.0 SFG
GOL
GOL
HOH
 7.367
5.312
7.334
2.667
 CG1
CG2
CG2
O
 OXT
C1
C3
O
3cbm 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 VAL A:174 A:284 50.0 0.323 T -59.3 -28.0 50.0 0.323 0.0 SAH
BME
HOH
 7.271
3.954
2.895
 CG2
O
N
 OXT
S2
O
3cbo 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 VAL A:174 A:284 48.0 0.31 T -59.4 -30.4 48.0 0.31 0.0 SAH
BME
HOH
 7.165
3.716
2.929
 CG2
O
N
 OXT
C1
O
3cbp 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 VAL A:174 A:284 50.0 0.323 T -57.7 -30.2 50.0 0.323 0.0 SFG
BME
HOH
 7.258
3.590
2.779
 CG2
O
N
 OXT
S2
O
3os5 1 Q8WTS6 100.0 0.0 X-RAY
 2010-12-15 VAL A:174 A:284 50.0 0.323 T -60.2 -23.7 50.0 0.323 0.0 EDO
SAH
HOH
 5.971
7.163
2.904
 N
CG2
N
 C2
OXT
O
4j7f 1 Q8WTS6 99.61 0.0 X-RAY
 2014-03-26 VAL A:179 A:284 54.0 0.348 T -65.2 -21.8 54.0 0.348 0.0 SAH
HOH
 7.351
2.682
 CG1
O
 OXT
O
3m57 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 VAL A:179 A:284 52.0 0.335 T -64.5 -14.7 52.0 0.335 0.0 SAH
HOH
 7.548
2.941
 CG1
N
 O
O
3m58 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 VAL A:179 A:284 54.0 0.348 T -56.1 -30.4 54.0 0.348 0.0 SO4
HOH
 3.358
2.789
 N
O
 O2
O
3m59 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 VAL A:179 A:284 50.0 0.323 T -60.7 -25.9 50.0 0.323 0.0 SAH
CO
HOH
 7.371
4.257
2.697
 CG2
N
O
 O
CO
O
3m5a 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 VAL A:179 A:284 50.0 0.323 T -63.4 -24.8 50.0 0.323 0.0 SAH
CO
CO
HOH
 7.453
4.308
8.751
2.925
 CG2
N
N
N
 O
CO
CO
O
1muf 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-06 VAL A:204 A:284 41.0 0.265 T -59.2 -19.8 41.0 0.265 0.0 HOH
 3.120
 N
 O
5ayf 1 Q8WTS6 94.92 0.0 X-RAY
 2016-04-27 VAL A:181 A:284 50.0 0.323 T -59.3 -27.2 50.0 0.323 0.0 SAM
HOH
 7.406
2.821
 CG2
O
 OXT
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8wts6-f1 1 Q8WTS6 100.0 0.0 VAL A:284 A:284 46.0 0.297 T -58.5 -28.1