Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 140439154 . G A CCDS3748.1:NM_030648.2:c.805Ctt>Ttt_NP_085151.1:p.269L>F Homo sapiens SET domain containing (lysine methyltransferase) 7 (SETD7), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1n6c 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-04 LEU A:200 A:269 12.0 0.071 -86.9 -51.2 12.0 0.071 0.0 HOH
 4.036
 CD2
 O
1h3i 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-11 LEU A:218 A:269 8.0 0.047 -95.1 -43.0 8.0 0.047 0.0 HOH
 3.643
 CD1
 O
LEU B:218 B:269 12.0 0.071 -89.3 -49.2 NA NA NA
1mt6 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-06 LEU A:212 A:269 13.0 0.076 -90.1 -52.2 13.0 0.076 0.0 HOH
 3.481
 CD1
 O
1n6a 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-04 LEU A:162 A:269 6.0 0.035 -95.8 -46.7 6.0 0.035 0.0 HOH
 3.368
 O
 O
1o9s 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-06 LEU A:162 A:269 15.0 0.088 -87.8 -56.8 15.0 0.088 0.0 HOH
 3.594
 CD2
 O
LEU B:162 B:269 17.0 0.1 -97.0 -56.5 NA NA NA
1xqh 1 Q8WTS6 100.0 0.0 X-RAY
 2004-11-23 LEU A:167 A:269 10.0 0.059 -93.6 -54.0 10.0 0.059 0.0 HOH
 3.486
 O
 O
LEU C:167 E:269 11.0 0.065 -95.4 -52.8 NA NA NA
4e47 1 Q8WTS6 100.0 0.0 X-RAY
 2012-03-28 LEU A:161 A:269 11.0 0.065 -93.0 -47.6 11.0 0.065 0.0 0N6
HOH
 5.979
3.095
 N
O
 O1
O
LEU B:161 B:269 12.0 0.071 -99.0 -49.5 NA NA NA
LEU C:161 C:269 10.0 0.059 -93.8 -45.9 NA NA NA
LEU D:161 D:269 13.0 0.076 -98.0 -46.1 NA NA NA
4jds 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 LEU A:161 A:269 11.0 0.065 -92.2 -50.0 11.0 0.065 0.0 1L4
UNX
UNX
UNX
HOH
 6.005
8.894
8.049
9.690
3.335
 N
O
N
CD2
O
 OAC
UNK
UNK
UNK
O
LEU B:161 B:269 10.0 0.059 -92.9 -49.3 NA NA NA
LEU C:161 C:269 11.0 0.065 -90.4 -49.6 NA NA NA
LEU D:161 D:269 10.0 0.059 -97.2 -49.6 NA NA NA
4jlg 1 Q8WTS6 100.0 0.0 X-RAY
 2013-04-17 LEU A:161 A:269 10.0 0.059 -91.9 -51.7 10.0 0.059 0.0 1L8
UNX
UNX
UNX
UNX
HOH
 5.992
3.556
5.009
6.685
3.715
4.095
 N
O
O
O
CD1
CD2
 OAB
UNK
UNK
UNK
UNK
O
LEU B:161 B:269 11.0 0.065 -97.0 -46.6 NA NA NA
2f69 1 Q8WTS6 100.0 0.0 X-RAY
 2006-01-17 LEU A:164 A:269 10.0 0.059 -96.5 -47.6 10.0 0.059 0.0 HOH
 2.674
 O
 O
3m53 1 Q8WTS6 100.0 0.0 X-RAY
 2010-07-28 LEU A:164 A:269 11.0 0.065 -97.8 -47.4 11.0 0.065 0.0 HOH
 4.021
 C
 O
4j83 1 Q8WTS6 100.0 0.0 X-RAY
 2014-01-08 LEU A:164 A:269 10.0 0.059 -97.2 -49.7 10.0 0.059 0.0 HOH
 4.065
 C
 O
4j8o 1 Q8WTS6 100.0 0.0 X-RAY
 2014-01-08 LEU A:164 A:269 9.0 0.053 -95.4 -51.4 9.0 0.053 0.0 HOH
 2.999
 O
 O
5eg2 1 Q8WTS6 99.23 0.0 X-RAY
 2016-01-13 LEU A:165 A:269 12.0 0.071 -97.6 -46.2 12.0 0.071 0.0 HOH
 3.556
 O
 O
3m54 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 LEU A:164 A:269 10.0 0.059 -98.4 -47.9 10.0 0.059 0.0 HOH
 4.035
 C
 O
3m55 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 LEU A:164 A:269 10.0 0.059 -98.5 -47.6 10.0 0.059 0.0 HOH
 3.875
 CD1
 O
3m56 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 LEU A:164 A:269 11.0 0.065 -97.8 -47.2 11.0 0.065 0.0 HOH
 3.807
 C
 O
4j7i 1 Q8WTS6 99.61 0.0 X-RAY
 2014-01-08 LEU A:164 A:269 15.0 0.088 -95.1 -61.3 15.0 0.088 0.0
3vuz 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 LEU A:166 A:269 6.0 0.035 -101.6 -43.1 6.0 0.035 0.0 K15
HOH
 9.783
4.597
 N
CD2
 C15
O
3vv0 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 LEU A:166 A:269 8.0 0.047 -95.7 -53.5 8.0 0.047 0.0 KH3
HOH
 8.695
3.342
 N
O
 C18
O
5ylt 1 Q8WTS6 100.0 0.0 X-RAY
 2018-06-20 LEU A:166 A:269 12.0 0.071 -90.3 -48.1 12.0 0.071 0.0 C7N
HOH
 9.358
3.190
 N
O
 C18
O
3cbm 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 LEU A:159 A:269 8.0 0.047 -91.5 -48.9 8.0 0.047 0.0 HOH
 3.397
 O
 O
3cbo 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 LEU A:159 A:269 9.0 0.053 -91.2 -43.4 9.0 0.053 0.0 HOH
 3.287
 O
 O
3cbp 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 LEU A:159 A:269 8.0 0.047 -95.1 -46.4 8.0 0.047 0.0 HOH
 4.198
 CD2
 O
3os5 1 Q8WTS6 100.0 0.0 X-RAY
 2010-12-15 LEU A:159 A:269 8.0 0.047 -90.4 -44.9 8.0 0.047 0.0 UNL
HOH
 9.367
4.103
 CD1
CD2
 O2
O
4j7f 1 Q8WTS6 99.61 0.0 X-RAY
 2014-03-26 LEU A:164 A:269 13.0 0.076 -98.7 -49.7 13.0 0.076 0.0 HOH
 3.737
 C
 O
3m57 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 LEU A:164 A:269 11.0 0.065 -100.2 -46.5 11.0 0.065 0.0 HOH
 3.683
 CD1
 O
3m58 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 LEU A:164 A:269 12.0 0.071 -96.9 -52.1 12.0 0.071 0.0 HOH
 2.676
 O
 O
3m59 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 LEU A:164 A:269 10.0 0.059 -99.5 -48.9 10.0 0.059 0.0 HOH
 2.710
 O
 O
3m5a 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 LEU A:164 A:269 8.0 0.047 -101.3 -44.6 8.0 0.047 0.0 HOH
 3.711
 CD1
 O
1muf 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-06 LEU A:189 A:269 14.0 0.082 E -85.7 -53.4 14.0 0.082 0.0 HOH
 3.735
 O
 O
5ayf 1 Q8WTS6 94.92 0.0 X-RAY
 2016-04-27 LEU A:166 A:269 8.0 0.047 -95.6 -50.8 8.0 0.047 0.0 C7H
HOH
 9.621
4.371
 N
CD2
 N
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8wts6-f1 1 Q8WTS6 100.0 0.0 LEU A:269 A:269 10.0 0.059 -88.8 -53.6