Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 140439162 . G A CCDS3748.1:NM_030648.2:c.797aCc>aTc_NP_085151.1:p.266T>I Homo sapiens SET domain containing (lysine methyltransferase) 7 (SETD7), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1n6c 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-04 THR A:197 A:266 37.0 0.264 -72.8 134.6 37.0 0.264 0.0 SAM
HOH
 6.330
3.741
 N
N
 CE
O
1h3i 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-11 THR A:215 A:266 11.0 0.079 E -98.4 145.7 11.0 0.079 0.0 MG
HOH
 7.620
4.005
 N
N
 MG
O
THR B:215 B:266 15.0 0.107 E -100.5 136.4 NA NA NA
1mt6 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-06 THR A:209 A:266 31.0 0.221 -81.8 144.0 31.0 0.221 0.0 SAH
HOH
 7.338
2.514
 N
O
 SD
O
1n6a 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-04 THR A:159 A:266 28.0 0.2 -87.4 135.7 28.0 0.2 0.0 SAM
HOH
 6.232
2.875
 N
O
 CE
O
1o9s 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-06 THR A:159 A:266 25.0 0.179 -73.1 132.7 0.0 0.0 0.179 C:Q16776:0.179
 SAH
HOH
 7.639
2.937
 N
OG1
 SD
O
THR B:159 B:266 27.0 0.193 -79.1 131.4 NA NA NA
1xqh 1 Q8WTS6 100.0 0.0 X-RAY
 2004-11-23 THR A:164 A:266 24.0 0.171 -74.0 135.8 0.0 0.0 0.171 B:P04637:0.171
 SAH
HOH
 7.579
2.818
 N
O
 SD
O
THR C:164 E:266 23.0 0.164 -74.1 134.7 NA NA NA
4e47 1 Q8WTS6 100.0 0.0 X-RAY
 2012-03-28 THR A:158 A:266 37.0 0.264 -82.4 106.2 37.0 0.264 0.0 SAM
0N6
HOH
 6.469
3.131
3.874
 N
OG1
N
 CE
C19
O
THR B:158 B:266 35.0 0.25 -83.5 111.7 NA NA NA
THR C:158 C:266 34.0 0.243 -80.8 107.9 NA NA NA
THR D:158 D:266 33.0 0.236 -84.2 103.9 NA NA NA
4jds 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 THR A:158 A:266 0.0 0.0 -84.0 109.9 0.0 0.0 0.0 SAM
1L4
UNX
HOH
 6.519
3.193
6.839
3.910
 N
O
O
N
 CE
CAR
UNK
O
THR B:158 B:266 0.0 0.0 -82.3 110.6 NA NA NA
THR C:158 C:266 0.0 0.0 -83.6 107.7 NA NA NA
THR D:158 D:266 0.0 0.0 -80.8 102.3 NA NA NA
4jlg 1 Q8WTS6 100.0 0.0 X-RAY
 2013-04-17 THR A:158 A:266 0.0 0.0 -87.2 104.8 0.0 0.0 0.0 SAM
1L8
UNX
UNX
HOH
 6.383
3.048
9.133
8.617
3.889
 N
O
O
O
N
 CE
CAR
UNK
UNK
O
THR B:158 B:266 0.0 0.0 -83.2 103.7 NA NA NA
2f69 1 Q8WTS6 100.0 0.0 X-RAY
 2006-01-17 THR A:161 A:266 23.0 0.164 -74.2 134.4 0.0 0.0 0.164 B:None:0.164
 SAH
HOH
 7.402
2.868
 N
O
 C5'
O
3m53 1 Q8WTS6 100.0 0.0 X-RAY
 2010-07-28 THR A:161 A:266 23.0 0.164 -76.4 132.1 0.0 0.0 0.164 B:None:0.164
 SAH
HOH
 7.239
2.881
 N
O
 C5'
O
4j83 1 Q8WTS6 100.0 0.0 X-RAY
 2014-01-08 THR A:161 A:266 23.0 0.164 -84.2 131.5 1.0 0.007 0.157 B:Q12962:0.157
 SAM
HOH
 6.272
2.928
 N
O
 CE
O
4j8o 1 Q8WTS6 100.0 0.0 X-RAY
 2014-01-08 THR A:161 A:266 23.0 0.164 -85.9 132.1 2.0 0.014 0.15 B:Q12962:0.15
 SAH
HOH
 7.109
2.866
 N
O
 C5'
O
5eg2 1 Q8WTS6 99.23 0.0 X-RAY
 2016-01-13 THR A:162 A:266 24.0 0.171 -78.6 133.8 0.0 0.0 0.171 B:Q12962:0.171
 SAH
HOH
 7.175
2.894
 N
O
 C5'
O
3m54 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 THR A:161 A:266 23.0 0.164 -73.0 136.3 0.0 0.0 0.164 B:None:0.164
 SAH
HOH
 7.202
2.810
 N
O
 SD
O
3m55 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 THR A:161 A:266 23.0 0.164 -72.4 134.8 0.0 0.0 0.164 B:None:0.164
 SAH
HOH
 7.488
2.856
 N
O
 C5'
O
3m56 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 THR A:161 A:266 23.0 0.164 -71.3 139.2 0.0 0.0 0.164 B:None:0.164
 SAH
HOH
 7.536
2.861
 N
O
 C5'
O
4j7i 1 Q8WTS6 99.61 0.0 X-RAY
 2014-01-08 THR A:161 A:266 23.0 0.164 -75.8 132.0 0.0 0.0 0.164 B:Q12962:0.164
 SAH
HOH
 7.366
7.936
 N
O
 C5'
O
3vuz 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 THR A:163 A:266 15.0 0.107 -89.9 135.3 15.0 0.107 0.0 K15
HOH
 3.264
5.284
 O
CG2
 C15
O
3vv0 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 THR A:163 A:266 20.0 0.143 -81.5 129.7 20.0 0.143 0.0 KH3
HOH
 3.136
3.747
 O
N
 C15
O
5ylt 1 Q8WTS6 100.0 0.0 X-RAY
 2018-06-20 THR A:163 A:266 27.0 0.193 -79.9 144.1 27.0 0.193 0.0 SFG
C7N
GOL
HOH
 6.145
2.594
6.115
2.866
 N
O
N
OG1
 NE
N16
C3
O
3cbm 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 THR A:156 A:266 23.0 0.164 -70.5 136.6 0.0 0.0 0.164 B:None:0.164
 SAH
HOH
 7.554
2.798
 N
O
 SD
O
3cbo 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 THR A:156 A:266 24.0 0.171 -73.8 135.5 0.0 0.0 0.171 B:P03372:0.171
 SAH
HOH
 7.463
2.906
 N
O
 SD
O
3cbp 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 THR A:156 A:266 24.0 0.171 -81.6 133.1 0.0 0.0 0.171 B:P03372:0.171
 SFG
HOH
 6.257
2.814
 N
O
 NE
O
3os5 1 Q8WTS6 100.0 0.0 X-RAY
 2010-12-15 THR A:156 A:266 25.0 0.179 -77.0 135.5 0.0 0.0 0.179 B:None:0.179
 SAH
HOH
 7.498
2.857
 N
O
 SD
O
4j7f 1 Q8WTS6 99.61 0.0 X-RAY
 2014-03-26 THR A:161 A:266 22.0 0.157 -77.4 130.7 0.0 0.0 0.157 B:Q12962:0.157
 SAH
HOH
 7.487
2.838
 N
O
 SD
O
3m57 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 THR A:161 A:266 26.0 0.186 -80.8 131.1 0.0 0.0 0.186 B:None:0.186
 SAH
HOH
 7.126
2.934
 N
O
 SD
O
3m58 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 THR A:161 A:266 22.0 0.157 -52.1 130.9 0.0 0.0 0.157 B:None:0.157
 SAH
HOH
 7.138
2.895
 N
O
 C5'
O
3m59 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 THR A:161 A:266 26.0 0.186 -73.6 135.6 0.0 0.0 0.186 B:None:0.186
 SAH
HOH
 7.203
2.868
 N
O
 C5'
O
3m5a 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 THR A:161 A:266 27.0 0.193 -80.5 141.0 0.0 0.0 0.193 B:None:0.193
 SAH
HOH
 7.078
2.983
 N
OG1
 SD
O
1muf 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-06 THR A:186 A:266 29.0 0.207 E -101.3 144.6 29.0 0.207 0.0 HOH
 3.446
 O
 O
5ayf 1 Q8WTS6 94.92 0.0 X-RAY
 2016-04-27 THR A:163 A:266 34.0 0.243 -77.2 144.9 34.0 0.243 0.0 SAM
C7H
HOH
 5.985
2.675
2.945
 N
O
OG1
 CE
N
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8wts6-f1 1 Q8WTS6 100.0 0.0 THR A:266 A:266 28.0 0.2 E -84.8 131.0