Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr4 140441448 . G A CCDS3748.1:NM_030648.2:c.745Cga>Tga_NP_085151.1:p.249R>* Homo sapiens SET domain containing (lysine methyltransferase) 7 (SETD7), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1n6c 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-04 ARG A:180 A:249 31.0 0.138 E -110.5 120.9 31.0 0.138 0.0 HOH
 2.903
 NH2
 O
1h3i 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-11 ARG A:198 A:249 34.0 0.151 E -107.7 113.2 34.0 0.151 0.0 HOH
 2.415
 NH1
 O
ARG B:198 B:249 34.0 0.151 E -113.0 106.8 NA NA NA
1mt6 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-06 ARG A:192 A:249 31.0 0.138 E -94.1 119.1 31.0 0.138 0.0 HOH
 2.935
 NH2
 O
1n6a 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-04 ARG A:142 A:249 28.0 0.124 E -109.1 118.7 28.0 0.124 0.0 HOH
 2.662
 O
 O
1o9s 1 Q8WTS6 100.0 0.0 X-RAY
 2003-02-06 ARG A:142 A:249 61.0 0.271 E -100.9 129.0 61.0 0.271 0.0 HOH
 2.842
 CD
 O
ARG B:142 B:249 34.0 0.151 E -106.3 110.9 NA NA NA
1xqh 1 Q8WTS6 100.0 0.0 X-RAY
 2004-11-23 ARG A:147 A:249 33.0 0.147 E -112.3 115.1 33.0 0.147 0.0 HOH
 2.761
 O
 O
ARG C:147 E:249 33.0 0.147 E -111.7 118.9 NA NA NA
4e47 1 Q8WTS6 100.0 0.0 X-RAY
 2012-03-28 ARG A:141 A:249 32.0 0.142 E -104.6 114.9 32.0 0.142 0.0 HOH
 2.740
 O
 O
ARG B:141 B:249 32.0 0.142 E -110.8 113.7 NA NA NA
ARG C:141 C:249 35.0 0.156 E -105.6 111.2 NA NA NA
ARG D:141 D:249 32.0 0.142 E -104.0 108.9 NA NA NA
4jds 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 ARG A:141 A:249 36.0 0.16 E -106.3 114.8 36.0 0.16 0.0 UNX
HOH
 7.093
2.965
 NH2
NH1
 UNK
O
ARG B:141 B:249 27.0 0.12 E -111.5 117.9 NA NA NA
ARG C:141 C:249 36.0 0.16 E -105.6 110.8 NA NA NA
ARG D:141 D:249 39.0 0.173 E -99.0 105.8 NA NA NA
4jlg 1 Q8WTS6 100.0 0.0 X-RAY
 2013-04-17 ARG A:141 A:249 31.0 0.138 E -106.5 116.7 31.0 0.138 0.0 UNX
HOH
 6.939
2.821
 NH1
O
 UNK
O
ARG B:141 B:249 38.0 0.169 E -112.4 112.9 NA NA NA
2f69 1 Q8WTS6 100.0 0.0 X-RAY
 2006-01-17 ARG A:144 A:249 26.0 0.116 E -113.4 113.5 26.0 0.116 0.0 HOH
 2.896
 O
 O
3m53 1 Q8WTS6 100.0 0.0 X-RAY
 2010-07-28 ARG A:144 A:249 33.0 0.147 E -114.8 111.2 33.0 0.147 0.0 HOH
 3.017
 NH2
 O
4j83 1 Q8WTS6 100.0 0.0 X-RAY
 2014-01-08 ARG A:144 A:249 33.0 0.147 E -113.9 110.0 33.0 0.147 0.0 HOH
 2.846
 NH1
 O
4j8o 1 Q8WTS6 100.0 0.0 X-RAY
 2014-01-08 ARG A:144 A:249 31.0 0.138 E -110.4 119.9 31.0 0.138 0.0 HOH
 2.816
 NH1
 O
5eg2 1 Q8WTS6 99.23 0.0 X-RAY
 2016-01-13 ARG A:145 A:249 34.0 0.151 E -111.8 109.5 34.0 0.151 0.0 HOH
 2.790
 O
 O
3m54 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:144 A:249 32.0 0.142 E -113.8 112.0 32.0 0.142 0.0 HOH
 2.763
 O
 O
3m55 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:144 A:249 31.0 0.138 E -114.8 112.8 31.0 0.138 0.0 HOH
 2.895
 O
 O
3m56 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:144 A:249 33.0 0.147 E -112.3 112.6 33.0 0.147 0.0 HOH
 2.856
 O
 O
4j7i 1 Q8WTS6 99.61 0.0 X-RAY
 2014-01-08 ARG A:144 A:249 41.0 0.182 E -112.0 101.7 41.0 0.182 0.0
3vuz 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 ARG A:146 A:249 31.0 0.138 E -113.0 99.2 31.0 0.138 0.0 HOH
 2.755
 NH2
 O
3vv0 1 Q8WTS6 100.0 0.0 X-RAY
 2013-03-27 ARG A:146 A:249 31.0 0.138 E -113.8 106.6 31.0 0.138 0.0 HOH
 2.749
 O
 O
5ylt 1 Q8WTS6 100.0 0.0 X-RAY
 2018-06-20 ARG A:146 A:249 29.0 0.129 E -115.7 112.1 29.0 0.129 0.0 HOH
 2.773
 NH1
 O
3cbm 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 ARG A:139 A:249 33.0 0.147 E -107.5 116.7 33.0 0.147 0.0 BME
HOH
 8.576
2.937
 NE
NH2
 S2
O
3cbo 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 ARG A:139 A:249 25.0 0.111 E -110.3 119.0 25.0 0.111 0.0 BME
HOH
 8.202
2.881
 NE
NH2
 S2
O
3cbp 1 Q8WTS6 100.0 0.0 X-RAY
 2008-05-13 ARG A:139 A:249 31.0 0.138 E -109.1 116.1 31.0 0.138 0.0 BME
HOH
 8.192
2.819
 NE
NH1
 S2
O
3os5 1 Q8WTS6 100.0 0.0 X-RAY
 2010-12-15 ARG A:139 A:249 30.0 0.133 E -109.5 119.3 30.0 0.133 0.0 BME
HOH
 8.209
2.922
 NE
NH1
 S2
O
4j7f 1 Q8WTS6 99.61 0.0 X-RAY
 2014-03-26 ARG A:144 A:249 32.0 0.142 E -111.3 110.2 32.0 0.142 0.0 HOH
 2.892
 NH2
 O
3m57 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:144 A:249 33.0 0.147 E -108.0 111.5 33.0 0.147 0.0 HOH
 2.991
 NH2
 O
3m58 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:144 A:249 26.0 0.116 E -108.5 110.6 26.0 0.116 0.0 HOH
 2.922
 NH2
 O
3m59 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:144 A:249 27.0 0.12 E -114.9 109.3 27.0 0.12 0.0 HOH
 2.795
 NH1
 O
3m5a 1 Q8WTS6 99.61 0.0 X-RAY
 2010-07-28 ARG A:144 A:249 28.0 0.124 E -106.9 107.9 28.0 0.124 0.0 HOH
 2.966
 NH2
 O
1muf 1 Q8WTS6 100.0 0.0 X-RAY
 2002-11-06 ARG A:169 A:249 29.0 0.129 E -105.8 117.7 29.0 0.129 0.0 HOH
 2.678
 NH1
 O
5ayf 1 Q8WTS6 94.92 0.0 X-RAY
 2016-04-27 ARG A:146 A:249 31.0 0.138 E -108.5 116.8 31.0 0.138 0.0 HOH
 2.927
 NH2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q8wts6-f1 1 Q8WTS6 100.0 0.0 ARG A:249 A:249 32.0 0.142 E -107.5 107.8