Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 158743699 | . | G | A | CCDS4346.1:NM_002187.2:c.981tgC>tgT_NP_002178.2:p.327C>C | Homo sapiens interleukin 12B (IL12B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4grw | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2014-02-19 | CYS | B:327 | B:305 | 56.0 | 0.415 | -66.5 | 360.0 | 56.0 | 0.415 | 0.0 |
HOH |
2.701 |
O |
O |
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CYS | D:327 | D:305 | 43.0 | 0.319 | -65.4 | 360.0 | NA | NA | NA | ||||||||||||||
5mxa | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | CYS | B:327 | A:327 | 13.0 | 0.096 | -77.4 | 160.9 | 13.0 | 0.096 | 0.0 | |||||||
5mzv | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | CYS | A:327 | A:327 | 66.0 | 0.489 | -63.2 | 360.0 | 66.0 | 0.489 | 0.0 | |||||||
5njd | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | CYS | A:327 | A:327 | 5.0 | 0.037 | -93.0 | 158.7 | 5.0 | 0.037 | 0.0 | |||||||
CYS | C:327 | C:327 | 6.0 | 0.044 | -96.8 | 159.3 | NA | NA | NA | ||||||||||||||
CYS | E:327 | E:327 | 5.0 | 0.037 | -98.7 | 157.1 | NA | NA | NA | ||||||||||||||
CYS | G:327 | G:327 | 50.0 | 0.37 | -124.2 | 360.0 | NA | NA | NA | ||||||||||||||
CYS | I:327 | I:327 | 6.0 | 0.044 | -84.8 | 133.3 | NA | NA | NA | ||||||||||||||
CYS | K:327 | K:327 | 4.0 | 0.03 | -92.9 | 152.5 | NA | NA | NA | ||||||||||||||
6wdq | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | CYS | A:307 | A:327 | 63.0 | 0.467 | -69.5 | 360.0 | 63.0 | 0.467 | 0.0 | |||||||
3duh | 1 | P29460 | 99.35 | 0.0 |
X-RAY |
2008-08-19 | CYS | A:307 | A:305 | 31.0 | 0.23 | -44.9 | -24.2 | 31.0 | 0.23 | 0.0 |
HOH |
8.438 |
SG |
O |
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CYS | B:307 | B:305 | 53.0 | 0.393 | -70.9 | 360.0 | NA | NA | NA | ||||||||||||||
1f42 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-13 | CYS | A:305 | A:305 | 31.0 | 0.23 | -89.5 | -14.8 | 31.0 | 0.23 | 0.0 | |||||||
1f45 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-20 | CYS | A:305 | A:305 | 16.0 | 0.119 | -58.0 | -43.1 | 16.0 | 0.119 | 0.0 | |||||||
3hmx | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2010-06-09 | CYS | A:305 | A:305 | 50.0 | 0.37 | -79.7 | 360.0 | 50.0 | 0.37 | 0.0 | |||||||
3qwr | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | CYS | A:305 | A:305 | 54.0 | 0.4 | -69.3 | 360.0 | 54.0 | 0.4 | 0.0 | |||||||
5mj3 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | CYS | A:305 | A:327 | 12.0 | 0.089 | -70.2 | 161.3 | 12.0 | 0.089 | 0.0 |
NA HOH |
8.460 4.130 |
HB3 C |
NA O |
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5mj4 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | CYS | A:305 | A:327 | 11.0 | 0.081 | -70.8 | 162.0 | 11.0 | 0.081 | 0.0 | |||||||
6uib | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2020-07-15 | CYS | B:309 | B:305 | 69.0 | 0.511 | -71.3 | 360.0 | 69.0 | 0.511 | 0.0 | |||||||
3d85 | 4 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | CYS | D:305 | D:305 | 50.0 | 0.37 | -69.7 | 360.0 | 50.0 | 0.37 | 0.0 |
HOH |
7.382 |
SG |
O |
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3d87 | 2 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | CYS | B:305 | B:305 | 22.0 | 0.163 | -64.0 | 140.0 | 22.0 | 0.163 | 0.0 | |||||||
CYS | D:305 | D:305 | 66.0 | 0.489 | -21.3 | 360.0 | 66.0 | 0.489 | 0.0 |
MAN |
8.281 |
SG |
C1 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29460-f1 | 1 | P29460 | 100.0 | 0.0 | CYS | A:327 | A:327 | 9.0 | 0.067 | -72.7 | 132.6 |