Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 158743707 | . | C | A | CCDS4346.1:NM_002187.2:c.973Gtg>Ttg_NP_002178.2:p.325V>L | Homo sapiens interleukin 12B (IL12B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4grw | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2014-02-19 | VAL | B:325 | B:303 | 32.0 | 0.206 | E | -147.7 | 133.1 | 32.0 | 0.206 | 0.0 |
HOH |
3.842 |
CG2 |
O |
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VAL | D:325 | D:303 | 35.0 | 0.226 | E | -146.2 | 131.9 | NA | NA | NA | |||||||||||||
5mxa | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | VAL | B:325 | A:325 | 34.0 | 0.219 | E | -142.7 | 134.5 | 34.0 | 0.219 | 0.0 | ||||||
5mzv | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | VAL | A:325 | A:325 | 24.0 | 0.155 | E | -142.6 | 142.3 | 24.0 | 0.155 | 0.0 | ||||||
5njd | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | VAL | A:325 | A:325 | 31.0 | 0.2 | E | -147.8 | 122.2 | 31.0 | 0.2 | 0.0 | ||||||
VAL | C:325 | C:325 | 30.0 | 0.194 | E | -142.0 | 125.6 | NA | NA | NA | |||||||||||||
VAL | E:325 | E:325 | 32.0 | 0.206 | E | -145.8 | 129.9 | NA | NA | NA | |||||||||||||
VAL | G:325 | G:325 | 33.0 | 0.213 | E | -148.5 | 125.1 | NA | NA | NA | |||||||||||||
VAL | I:325 | I:325 | 31.0 | 0.2 | E | -144.7 | 127.1 | NA | NA | NA | |||||||||||||
VAL | K:325 | K:325 | 30.0 | 0.194 | E | -155.8 | 129.8 | NA | NA | NA | |||||||||||||
6wdq | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | VAL | A:305 | A:325 | 25.0 | 0.161 | E | -142.9 | 146.7 | 25.0 | 0.161 | 0.0 | ||||||
3duh | 1 | P29460 | 99.35 | 0.0 |
X-RAY |
2008-08-19 | VAL | A:305 | A:303 | 35.0 | 0.226 | E | -150.1 | 131.2 | 35.0 | 0.226 | 0.0 |
HOH |
6.128 |
N |
O |
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VAL | B:305 | B:303 | 32.0 | 0.206 | E | -154.5 | 128.1 | NA | NA | NA | |||||||||||||
1f42 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-13 | VAL | A:303 | A:303 | 22.0 | 0.142 | E | -135.3 | 132.7 | 22.0 | 0.142 | 0.0 |
HOH |
5.605 |
N |
O |
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1f45 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-20 | VAL | A:303 | A:303 | 30.0 | 0.194 | E | -151.9 | 145.1 | 30.0 | 0.194 | 0.0 | ||||||
3hmx | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2010-06-09 | VAL | A:303 | A:303 | 31.0 | 0.2 | B | -172.3 | 151.0 | 31.0 | 0.2 | 0.0 | ||||||
3qwr | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | VAL | A:303 | A:303 | 27.0 | 0.174 | E | -141.3 | 134.4 | 27.0 | 0.174 | 0.0 | ||||||
5mj3 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | VAL | A:303 | A:325 | 31.0 | 0.2 | E | -140.3 | 135.0 | 31.0 | 0.2 | 0.0 |
HOH |
2.991 |
HA |
O |
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5mj4 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | VAL | A:303 | A:325 | 35.0 | 0.226 | E | -144.9 | 134.3 | 35.0 | 0.226 | 0.0 | ||||||
6uib | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2020-07-15 | VAL | B:307 | B:303 | 30.0 | 0.194 | E | -149.4 | 134.8 | 30.0 | 0.194 | 0.0 | ||||||
3d85 | 4 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | VAL | D:303 | D:303 | 27.0 | 0.174 | E | -142.1 | 142.8 | 27.0 | 0.174 | 0.0 |
HOH |
5.439 |
N |
O |
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3d87 | 2 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | VAL | B:303 | B:303 | 36.0 | 0.232 | E | -140.6 | 121.9 | 36.0 | 0.232 | 0.0 | ||||||
VAL | D:303 | D:303 | 48.0 | 0.31 | -149.8 | 61.5 | 48.0 | 0.31 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29460-f1 | 1 | P29460 | 100.0 | 0.0 | VAL | A:325 | A:325 | 30.0 | 0.194 | E | -136.8 | 134.8 |