Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 158743742 . C A CCDS4346.1:NM_002187.2:c.938cGc>cTc_NP_002178.2:p.313R>L Homo sapiens interleukin 12B (IL12B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4grw 2 P29460 100.0 0.0 X-RAY
 2014-02-19 ARG B:313 B:291 78.0 0.347 S -66.4 -29.8 55.0 0.244 0.103 A:Q9NPF7:0.102
 HOH
 2.809
 NH2
 O
ARG D:313 D:291 78.0 0.347 S -65.9 -30.2 NA NA NA
5mxa 2 P29460 100.0 0.0 X-RAY
 2017-12-20 ARG B:313 A:313 75.0 0.333 S -74.1 -32.2 53.0 0.236 0.097 A:Q9NPF7:0.098
 HOH
 3.613
 H
 O
5mzv 1 P29460 100.0 0.0 X-RAY
 2018-01-03 ARG A:313 A:313 76.0 0.338 T -66.1 -37.8 54.0 0.24 0.098 B:Q9NPF7:0.098
5njd 1 P29460 100.0 0.0 X-RAY
 2018-01-03 ARG A:313 A:313 88.0 0.391 S -70.1 -29.7 57.0 0.253 0.138 B:Q9NPF7:0.138
ARG C:313 C:313 88.0 0.391 S -69.4 -24.1 NA NA NA
ARG E:313 E:313 81.0 0.36 S -65.2 -27.4 NA NA NA
ARG G:313 G:313 91.0 0.404 S -70.1 -26.7 NA NA NA
ARG I:313 I:313 93.0 0.413 S -60.7 -33.5 NA NA NA
ARG K:313 K:313 89.0 0.396 S -77.0 -12.6 NA NA NA
6wdq 1 P29460 100.0 0.0 X-RAY
 2021-02-24 ARG A:293 A:313 79.0 0.351 S -74.9 -37.6 59.0 0.262 0.089 B:Q9NPF7:0.089
3duh 1 P29460 99.35 0.0 X-RAY
 2008-08-19 ARG A:293 A:291 76.0 0.338 S -64.5 -40.8 58.0 0.258 0.08 C:Q9NPF7:0.08
 HOH
 3.199
 O
 O
ARG B:293 B:291 77.0 0.342 S -60.8 -32.4 NA NA NA
1f42 1 P29460 100.0 0.0 X-RAY
 2001-06-13 ARG A:291 A:291 82.0 0.364 T -53.7 -38.3 82.0 0.364 0.0 HOH
 3.204
 O
 O
1f45 1 P29460 100.0 0.0 X-RAY
 2001-06-20 ARG A:291 A:291 123.0 0.547 S -76.6 -17.5 54.0 0.24 0.307 B:P29459:0.307
 HOH
 4.097
 N
 O
3hmx 1 P29460 100.0 0.0 X-RAY
 2010-06-09 ARG A:291 A:291 111.0 0.493 S -52.8 -45.8 77.0 0.342 0.151 B:P29459:0.151
3qwr 1 P29460 100.0 0.0 X-RAY
 2012-02-01 ARG A:291 A:291 68.0 0.302 S -66.8 -29.8 39.0 0.173 0.129 B:Q9NPF7:0.129
5mj3 1 P29460 100.0 0.0 X-RAY
 2017-01-11 ARG A:291 A:313 75.0 0.333 S -65.3 -31.9 50.0 0.222 0.111 B:Q9NPF7:0.111
 HOH
 2.302
 HH22
 O
5mj4 1 P29460 100.0 0.0 X-RAY
 2017-01-11 ARG A:291 A:313 79.0 0.351 S -66.4 -32.3 56.0 0.249 0.102 B:Q9NPF7:0.102
6uib 2 P29460 100.0 0.0 X-RAY
 2020-07-15 ARG B:295 B:291 94.0 0.418 S -67.4 -27.5 7.0 0.031 0.387 A:Q9NPF7:0.187
C:None:0.298
 HOH
 3.131
 NE
 O
3d85 4 P29460 99.67 0.0 X-RAY
 2008-09-02 ARG D:291 D:291 77.0 0.342 S -68.7 -27.2 57.0 0.253 0.089 C:Q9NPF7:0.089
 HOH
 2.901
 O
 O
3d87 2 P29460 99.67 0.0 X-RAY
 2008-09-02 ARG B:291 B:291 70.0 0.311 S -71.5 -27.1 55.0 0.244 0.067 A:Q9NPF7:0.067
ARG D:291 D:291 71.0 0.316 S -60.1 -30.7 46.0 0.204 0.112 C:Q9NPF7:0.111

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p29460-f1 1 P29460 100.0 0.0 ARG A:313 A:313 68.0 0.302 S -70.4 -34.7