Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 158743780 | . | G | A | CCDS4346.1:NM_002187.2:c.900tgC>tgT_NP_002178.2:p.300C>C | Homo sapiens interleukin 12B (IL12B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4grw | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2014-02-19 | CYS | B:300 | B:278 | 8.0 | 0.059 | -90.1 | 128.1 | 8.0 | 0.059 | 0.0 |
HOH |
6.071 |
N |
O |
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CYS | D:300 | D:278 | 37.0 | 0.274 | -85.4 | 122.0 | NA | NA | NA | ||||||||||||||
5mxa | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | CYS | B:300 | A:300 | 17.0 | 0.126 | -98.2 | 132.0 | 17.0 | 0.126 | 0.0 | |||||||
5mzv | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | CYS | A:300 | A:300 | 10.0 | 0.074 | -101.9 | 152.8 | 10.0 | 0.074 | 0.0 | |||||||
5njd | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | CYS | A:300 | A:300 | 13.0 | 0.096 | -103.2 | 155.9 | 13.0 | 0.096 | 0.0 | |||||||
CYS | C:300 | C:300 | 8.0 | 0.059 | -103.2 | 150.7 | NA | NA | NA | ||||||||||||||
CYS | E:300 | E:300 | 23.0 | 0.17 | -101.0 | 154.3 | NA | NA | NA | ||||||||||||||
CYS | G:300 | G:300 | 45.0 | 0.333 | -103.7 | 149.6 | NA | NA | NA | ||||||||||||||
CYS | I:300 | I:300 | 31.0 | 0.23 | -96.6 | 159.0 | NA | NA | NA | ||||||||||||||
CYS | K:300 | K:300 | 23.0 | 0.17 | -109.4 | 148.7 | NA | NA | NA | ||||||||||||||
6wdq | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | CYS | A:280 | A:300 | 21.0 | 0.156 | -93.7 | 153.4 | 21.0 | 0.156 | 0.0 | |||||||
3duh | 1 | P29460 | 99.35 | 0.0 |
X-RAY |
2008-08-19 | CYS | A:280 | A:278 | 24.0 | 0.178 | -86.7 | 162.3 | 24.0 | 0.178 | 0.0 |
HOH |
9.729 |
SG |
O |
|||
CYS | B:280 | B:278 | 13.0 | 0.096 | -85.9 | 113.4 | NA | NA | NA | ||||||||||||||
1f42 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-13 | CYS | A:278 | A:278 | 24.0 | 0.178 | -89.7 | 158.5 | 24.0 | 0.178 | 0.0 |
HOH |
8.834 |
CB |
O |
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1f45 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-20 | CYS | A:278 | A:278 | 24.0 | 0.178 | -82.1 | 160.3 | 24.0 | 0.178 | 0.0 | |||||||
3hmx | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2010-06-09 | CYS | A:278 | A:278 | 39.0 | 0.289 | -77.5 | 170.3 | 39.0 | 0.289 | 0.0 | |||||||
3qwr | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | CYS | A:278 | A:278 | 33.0 | 0.244 | -72.1 | 114.1 | 33.0 | 0.244 | 0.0 | |||||||
5mj3 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | CYS | A:278 | A:300 | 6.0 | 0.044 | -89.1 | 167.1 | 6.0 | 0.044 | 0.0 |
NA HOH |
6.639 4.482 |
HB2 HB2 |
NA O |
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5mj4 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | CYS | A:278 | A:300 | 44.0 | 0.326 | -87.0 | 82.9 | 44.0 | 0.326 | 0.0 | |||||||
6uib | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2020-07-15 | CYS | B:282 | B:278 | 17.0 | 0.126 | -98.0 | 132.4 | 17.0 | 0.126 | 0.0 | |||||||
3d85 | 4 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | CYS | D:278 | D:278 | 27.0 | 0.2 | -76.1 | 112.4 | 27.0 | 0.2 | 0.0 |
HOH |
5.082 |
O |
O |
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3d87 | 2 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | CYS | B:278 | B:278 | 8.0 | 0.059 | -68.7 | 128.6 | 8.0 | 0.059 | 0.0 | |||||||
CYS | D:278 | D:278 | 22.0 | 0.163 | -105.0 | 128.1 | 22.0 | 0.163 | 0.0 |
MAN |
9.755 |
C |
O5 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29460-f1 | 1 | P29460 | 100.0 | 0.0 | CYS | A:300 | A:300 | 15.0 | 0.111 | -81.3 | 124.4 |