Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 158743817 | . | C | A | CCDS4346.1:NM_002187.2:c.863aGa>aTa_NP_002178.2:p.288R>I | Homo sapiens interleukin 12B (IL12B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4grw | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2014-02-19 | ARG | B:288 | B:266 | 136.0 | 0.604 | E | -110.3 | 147.8 | 73.0 | 0.324 | 0.28 |
J:None:0.28 |
HOH |
4.704 |
NH2 |
O |
|
ARG | D:288 | D:266 | 120.0 | 0.533 | E | -108.2 | 134.7 | NA | NA | NA | |||||||||||||
5mxa | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | ARG | B:288 | A:288 | 132.0 | 0.587 | E | -118.6 | 137.3 | 132.0 | 0.587 | 0.0 |
HOH |
2.266 |
HH22 |
O |
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5mzv | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | ARG | A:288 | A:288 | 110.0 | 0.489 | E | -85.1 | 138.5 | 110.0 | 0.489 | 0.0 | ||||||
5njd | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | ARG | A:288 | A:288 | 137.0 | 0.609 | E | -130.6 | 147.9 | 137.0 | 0.609 | 0.0 | ||||||
ARG | C:288 | C:288 | 166.0 | 0.738 | 360.0 | 153.4 | NA | NA | NA | ||||||||||||||
ARG | E:288 | E:288 | 171.0 | 0.76 | 360.0 | 151.2 | NA | NA | NA | ||||||||||||||
ARG | G:288 | G:288 | 159.0 | 0.707 | E | -90.7 | 143.5 | NA | NA | NA | |||||||||||||
ARG | I:288 | I:288 | 168.0 | 0.747 | 360.0 | 150.2 | NA | NA | NA | ||||||||||||||
ARG | K:288 | K:288 | 121.0 | 0.538 | E | -105.9 | 158.1 | NA | NA | NA | |||||||||||||
6wdq | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | ARG | A:268 | A:288 | 134.0 | 0.596 | -85.4 | 133.7 | 134.0 | 0.596 | 0.0 | |||||||
3duh | 1 | P29460 | 99.35 | 0.0 |
X-RAY |
2008-08-19 | ARG | A:268 | A:266 | 114.0 | 0.507 | E | -145.1 | 121.6 | 114.0 | 0.507 | 0.0 |
HOH |
4.335 |
O |
O |
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ARG | B:268 | B:266 | 101.0 | 0.449 | E | -127.4 | 135.0 | NA | NA | NA | |||||||||||||
1f42 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-13 | ARG | A:266 | A:266 | 211.0 | 0.938 | 360.0 | 111.7 | 211.0 | 0.938 | 0.0 |
MNB |
2.656 |
NH1 |
O12 |
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1f45 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-20 | ARG | A:266 | A:266 | 96.0 | 0.427 | E | -113.5 | 173.0 | 96.0 | 0.427 | 0.0 | ||||||
3hmx | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2010-06-09 | ARG | A:266 | A:266 | 54.0 | NA | -73.0 | 137.4 | 54.0 | NA | NA | |||||||
3qwr | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | ARG | A:266 | A:266 | 110.0 | 0.489 | E | -126.8 | 138.5 | 52.0 | 0.231 | 0.258 |
C:None:0.258 |
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5mj3 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ARG | A:266 | A:288 | 108.0 | 0.48 | E | -129.9 | 145.1 | 108.0 | 0.48 | 0.0 |
HOH |
1.792 |
HH11 |
O |
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5mj4 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ARG | A:266 | A:288 | 118.0 | 0.524 | E | -129.2 | 144.6 | 118.0 | 0.524 | 0.0 | ||||||
6uib | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2020-07-15 | ARG | B:270 | B:266 | 110.0 | 0.489 | E | -100.7 | 142.7 | 110.0 | 0.489 | 0.0 |
HOH |
5.230 |
NH1 |
O |
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3d85 | 4 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | ARG | D:266 | D:266 | 48.0 | NA | E | -132.0 | 141.6 | 48.0 | NA | NA |
HOH |
2.765 |
CD |
O |
||
3d87 | 2 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | ARG | B:266 | B:266 | 117.0 | 0.52 | E | -111.4 | 163.8 | 117.0 | 0.52 | 0.0 |
PO4 |
2.669 |
NH1 |
O3 |
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ARG | D:266 | D:266 | 19.0 | NA | -76.0 | 139.3 | 19.0 | NA | NA |
MAN PO4 |
9.740 6.971 |
N CB |
O6 O2 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29460-f1 | 1 | P29460 | 100.0 | 0.0 | ARG | A:288 | A:288 | 107.0 | 0.476 | E | -123.6 | 125.2 |