Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 158745868 | . | T | A | CCDS4346.1:NM_002187.2:c.731aAg>aTg_NP_002178.2:p.244K>M | Homo sapiens interleukin 12B (IL12B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4grw | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2014-02-19 | LYS | B:244 | B:222 | 119.0 | 0.595 | E | -116.3 | 107.2 | 119.0 | 0.595 | 0.0 |
HOH |
3.341 |
CE |
O |
||
LYS | D:244 | D:222 | 51.0 | NA | E | -90.7 | 102.1 | NA | NA | NA | |||||||||||||
5mxa | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | LYS | B:244 | A:244 | 126.0 | 0.63 | E | -125.3 | 110.3 | 126.0 | 0.63 | 0.0 | ||||||
5mzv | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | LYS | A:244 | A:244 | 147.0 | 0.735 | -163.7 | 131.8 | 147.0 | 0.735 | 0.0 | |||||||
5njd | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | LYS | A:244 | A:244 | 49.0 | NA | E | -122.6 | 104.6 | 49.0 | NA | NA | ||||||
LYS | C:244 | C:244 | 143.0 | 0.715 | E | -127.1 | 96.5 | NA | NA | NA | |||||||||||||
LYS | E:244 | E:244 | 139.0 | 0.695 | E | -130.4 | 105.2 | NA | NA | NA | |||||||||||||
LYS | G:244 | G:244 | 151.0 | 0.755 | E | -136.5 | 95.0 | NA | NA | NA | |||||||||||||
LYS | I:244 | I:244 | 146.0 | 0.73 | E | -129.1 | 103.6 | NA | NA | NA | |||||||||||||
LYS | K:244 | K:244 | 144.0 | 0.72 | E | -129.1 | 100.3 | NA | NA | NA | |||||||||||||
6wdq | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | LYS | A:224 | A:244 | 135.0 | 0.675 | E | -154.5 | 137.9 | 135.0 | 0.675 | 0.0 | ||||||
3duh | 1 | P29460 | 99.35 | 0.0 |
X-RAY |
2008-08-19 | LYS | A:224 | A:222 | 135.0 | 0.675 | E | -142.3 | 99.3 | 135.0 | 0.675 | 0.0 |
HOH |
3.503 |
CB |
O |
||
LYS | B:224 | B:222 | 99.0 | 0.495 | E | -115.5 | 123.3 | NA | NA | NA | |||||||||||||
1f42 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-13 | LYS | A:222 | A:222 | 115.0 | 0.575 | E | -121.5 | 104.5 | 115.0 | 0.575 | 0.0 |
HOH |
7.584 |
O |
O |
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1f45 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-20 | LYS | A:222 | A:222 | 121.0 | 0.605 | -157.0 | 61.9 | 121.0 | 0.605 | 0.0 | |||||||
3hmx | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2010-06-09 | LYS | A:222 | A:222 | 120.0 | 0.6 | -173.4 | 72.6 | 120.0 | 0.6 | 0.0 | |||||||
3qwr | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | LYS | A:222 | A:222 | 124.0 | 0.62 | E | -122.8 | 121.9 | 124.0 | 0.62 | 0.0 | ||||||
5mj3 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | LYS | A:222 | A:244 | 153.0 | 0.765 | E | -116.0 | 102.3 | 153.0 | 0.765 | 0.0 |
NA HOH |
6.980 2.856 |
O O |
NA O |
||
5mj4 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | LYS | A:222 | A:244 | 47.0 | NA | E | -115.2 | 106.4 | 47.0 | NA | NA | ||||||
6uib | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2020-07-15 | LYS | B:226 | B:222 | 47.0 | NA | E | -119.2 | 103.1 | 47.0 | NA | NA | ||||||
3d85 | 4 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | LYS | D:222 | D:222 | 46.0 | NA | E | -130.8 | 82.8 | 46.0 | NA | NA |
HOH |
3.619 |
CB |
O |
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3d87 | 2 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | LYS | B:222 | B:222 | 133.0 | 0.665 | -159.6 | 100.3 | 133.0 | 0.665 | 0.0 | |||||||
LYS | D:222 | D:222 | 173.0 | 0.865 | E | -149.6 | 91.0 | 173.0 | 0.865 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29460-f1 | 1 | P29460 | 100.0 | 0.0 | LYS | A:244 | A:244 | 133.0 | 0.665 | E | -114.7 | 111.3 |