Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 158747368 | . | C | A | CCDS4346.1:NM_002187.2:c.643Gtt>Ttt_NP_002178.2:p.215V>F | Homo sapiens interleukin 12B (IL12B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4grw | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2014-02-19 | VAL | B:215 | B:193 | 18.0 | 0.116 | E | -124.0 | 116.9 | 18.0 | 0.116 | 0.0 |
HOH |
3.091 |
O |
O |
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VAL | D:215 | D:193 | 17.0 | 0.11 | E | -125.2 | 116.7 | NA | NA | NA | |||||||||||||
5mxa | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | VAL | B:215 | A:215 | 26.0 | 0.168 | E | -119.3 | 128.5 | 26.0 | 0.168 | 0.0 |
NAG HOH |
9.397 6.996 |
HG23 H |
O7 O |
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5mzv | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | VAL | A:215 | A:215 | 22.0 | 0.142 | E | -126.4 | 133.4 | 22.0 | 0.142 | 0.0 |
NAG HOH |
9.539 3.192 |
HG23 HG23 |
O7 O |
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5njd | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | VAL | A:215 | A:215 | 24.0 | 0.155 | E | -133.4 | 114.3 | 24.0 | 0.155 | 0.0 |
NAG |
9.851 |
CG2 |
O7 |
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VAL | C:215 | C:215 | 26.0 | 0.168 | E | -134.8 | 112.4 | NA | NA | NA | |||||||||||||
VAL | E:215 | E:215 | 28.0 | 0.181 | E | -141.3 | 116.5 | NA | NA | NA | |||||||||||||
VAL | G:215 | G:215 | 27.0 | 0.174 | E | -138.8 | 109.5 | NA | NA | NA | |||||||||||||
VAL | I:215 | I:215 | 30.0 | 0.194 | E | -128.4 | 123.1 | NA | NA | NA | |||||||||||||
VAL | K:215 | K:215 | 26.0 | 0.168 | E | -137.2 | 120.0 | NA | NA | NA | |||||||||||||
6wdq | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | VAL | A:195 | A:215 | 28.0 | 0.181 | E | -133.0 | 116.7 | 28.0 | 0.181 | 0.0 | ||||||
3duh | 1 | P29460 | 99.35 | 0.0 |
X-RAY |
2008-08-19 | VAL | A:195 | A:193 | 16.0 | 0.103 | E | -118.8 | 116.2 | 16.0 | 0.103 | 0.0 |
NAG HOH |
9.993 3.060 |
CG2 O |
O7 O |
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VAL | B:195 | B:193 | 17.0 | 0.11 | E | -130.7 | 118.7 | NA | NA | NA | |||||||||||||
1f42 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-13 | VAL | A:193 | A:193 | 23.0 | 0.148 | E | -120.1 | 116.5 | 23.0 | 0.148 | 0.0 |
NAG HOH |
9.384 3.813 |
CG2 CG1 |
C8 O |
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1f45 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-20 | VAL | A:193 | A:193 | 8.0 | 0.052 | E | -136.9 | 104.5 | 8.0 | 0.052 | 0.0 |
NAG |
9.779 |
CG2 |
O7 |
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3hmx | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2010-06-09 | VAL | A:193 | A:193 | 10.0 | 0.065 | E | -121.6 | 118.2 | 10.0 | 0.065 | 0.0 |
NAG HOH |
9.625 3.923 |
CG2 CG2 |
O7 O |
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3qwr | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | VAL | A:193 | A:193 | 22.0 | 0.142 | E | -130.0 | 117.6 | 22.0 | 0.142 | 0.0 |
NAG |
9.535 |
CG2 |
O7 |
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5mj3 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | VAL | A:193 | A:215 | 25.0 | 0.161 | E | -128.0 | 122.3 | 25.0 | 0.161 | 0.0 |
NAG PG4 HOH |
9.556 2.575 3.026 |
HG22 HG21 HG23 |
H2 H31 O |
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5mj4 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | VAL | A:193 | A:215 | 22.0 | 0.142 | E | -127.8 | 122.6 | 22.0 | 0.142 | 0.0 |
NAG |
9.177 |
HG23 |
HN2 |
||
6uib | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2020-07-15 | VAL | B:197 | B:193 | 20.0 | 0.129 | E | -129.4 | 109.4 | 20.0 | 0.129 | 0.0 |
NAG HOH |
9.930 8.620 |
CG2 CG2 |
O7 O |
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3d85 | 4 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | VAL | D:193 | D:193 | 17.0 | 0.11 | E | -132.3 | 117.8 | 17.0 | 0.11 | 0.0 |
HOH |
3.161 |
O |
O |
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3d87 | 2 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | VAL | B:193 | B:193 | 7.0 | 0.045 | E | -100.8 | 115.5 | 7.0 | 0.045 | 0.0 | ||||||
VAL | D:193 | D:193 | 7.0 | 0.045 | -135.8 | 116.1 | 7.0 | 0.045 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29460-f1 | 1 | P29460 | 100.0 | 0.0 | VAL | A:215 | A:215 | 26.0 | 0.168 | E | -119.4 | 117.3 |