Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 158747374 | . | C | A | CCDS4346.1:NM_002187.2:c.637Gat>Tat_NP_002178.2:p.213D>Y | Homo sapiens interleukin 12B (IL12B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4grw | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2014-02-19 | ASP | B:213 | B:191 | 30.0 | 0.2 | E | -95.3 | 132.2 | 30.0 | 0.2 | 0.0 |
NAG NAG HOH |
3.884 9.248 3.534 |
OD1 OD1 O |
O7 O5 O |
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ASP | D:213 | D:191 | 37.0 | 0.247 | E | -95.8 | 133.0 | NA | NA | NA | |||||||||||||
5mxa | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | ASP | B:213 | A:213 | 41.0 | 0.273 | E | -88.4 | 139.2 | 41.0 | 0.273 | 0.0 |
NAG NAG HOH |
3.911 8.622 6.930 |
OD1 OD2 H |
H82 H62 O |
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5mzv | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | ASP | A:213 | A:213 | 24.0 | 0.16 | E | -94.8 | 141.5 | 24.0 | 0.16 | 0.0 |
NAG NAG HOH |
3.826 8.340 4.114 |
OD2 OD2 HB3 |
O7 H62 O |
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5njd | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | ASP | A:213 | A:213 | 26.0 | 0.173 | E | -103.5 | 127.6 | 26.0 | 0.173 | 0.0 |
NAG NAG |
3.258 9.242 |
OD1 OD1 |
O7 O5 |
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ASP | C:213 | C:213 | 30.0 | 0.2 | E | -101.0 | 132.6 | NA | NA | NA | |||||||||||||
ASP | E:213 | E:213 | 28.0 | 0.187 | E | -106.7 | 123.3 | NA | NA | NA | |||||||||||||
ASP | G:213 | G:213 | 32.0 | 0.213 | E | -98.7 | 134.6 | NA | NA | NA | |||||||||||||
ASP | I:213 | I:213 | 34.0 | 0.227 | E | -94.6 | 135.0 | NA | NA | NA | |||||||||||||
ASP | K:213 | K:213 | 36.0 | 0.24 | E | -102.0 | 125.9 | NA | NA | NA | |||||||||||||
6wdq | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | ASP | A:193 | A:213 | 44.0 | 0.293 | E | -98.6 | 134.4 | 44.0 | 0.293 | 0.0 |
NAG |
6.511 |
OD1 |
N2 |
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3duh | 1 | P29460 | 99.35 | 0.0 |
X-RAY |
2008-08-19 | ASP | A:193 | A:191 | 19.0 | 0.127 | E | -87.7 | 128.9 | 19.0 | 0.127 | 0.0 |
NAG HOH |
4.068 2.750 |
OD1 OD1 |
O7 O |
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ASP | B:193 | B:191 | 13.0 | 0.087 | E | -88.0 | 125.4 | NA | NA | NA | |||||||||||||
1f42 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-13 | ASP | A:191 | A:191 | 41.0 | 0.273 | E | -98.8 | 138.1 | 41.0 | 0.273 | 0.0 |
NAG NAG HOH |
3.400 9.111 2.745 |
OD1 OD1 OD1 |
C8 O5 O |
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1f45 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-20 | ASP | A:191 | A:191 | 38.0 | 0.253 | E | -98.2 | 127.4 | 38.0 | 0.253 | 0.0 |
NAG NAG |
3.529 9.195 |
OD1 OD1 |
O7 O5 |
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3hmx | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2010-06-09 | ASP | A:191 | A:191 | 18.0 | 0.12 | E | -91.4 | 116.4 | 18.0 | 0.12 | 0.0 |
NAG NAG HOH |
3.096 9.163 4.307 |
OD1 OD1 O |
O7 O5 O |
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3qwr | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | ASP | A:191 | A:191 | 38.0 | 0.253 | E | -91.0 | 122.8 | 38.0 | 0.253 | 0.0 |
NAG NAG |
3.376 8.596 |
OD1 OD1 |
O7 O5 |
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5mj3 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:191 | A:213 | 35.0 | 0.233 | E | -85.9 | 137.6 | 35.0 | 0.233 | 0.0 |
NAG NAG PG4 HOH |
3.990 8.660 3.629 2.625 |
OD1 OD1 HB2 OD1 |
O7 H62 H22 O |
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5mj4 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:191 | A:213 | 24.0 | 0.16 | E | -85.9 | 137.6 | 24.0 | 0.16 | 0.0 |
NAG NAG |
3.293 8.607 |
OD1 OD1 |
HN2 H62 |
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6uib | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2020-07-15 | ASP | B:195 | B:191 | 38.0 | 0.253 | E | -90.0 | 128.8 | 38.0 | 0.253 | 0.0 |
NAG NAG HOH |
3.979 9.130 2.610 |
OD1 OD1 OD2 |
O7 O5 O |
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3d85 | 4 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | ASP | D:191 | D:191 | 17.0 | 0.113 | E | -88.9 | 121.4 | 17.0 | 0.113 | 0.0 |
HOH |
2.937 |
OD2 |
O |
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3d87 | 2 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | ASP | B:191 | B:191 | 8.0 | 0.053 | E | -82.5 | 100.3 | 8.0 | 0.053 | 0.0 | ||||||
ASP | D:191 | D:191 | 15.0 | 0.1 | E | -87.9 | 93.4 | 15.0 | 0.1 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29460-f1 | 1 | P29460 | 100.0 | 0.0 | ASP | A:213 | A:213 | 7.0 | 0.047 | E | -79.0 | 124.8 |