Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 158747475 | . | C | A | CCDS4346.1:NM_002187.2:c.536aGa>aTa_NP_002178.2:p.179R>I | Homo sapiens interleukin 12B (IL12B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4grw | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2014-02-19 | ARG | B:179 | B:157 | 118.0 | 0.524 | E | -98.3 | 138.4 | 118.0 | 0.524 | 0.0 |
HOH |
3.389 |
NE |
O |
||
ARG | D:179 | D:157 | 77.0 | 0.342 | E | -168.3 | 163.5 | NA | NA | NA | |||||||||||||
5mxa | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | ARG | B:179 | A:179 | 133.0 | 0.591 | E | -123.2 | 122.7 | 133.0 | 0.591 | 0.0 |
HOH |
8.940 |
H |
O |
||
5mzv | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | ARG | A:179 | A:179 | 97.0 | 0.431 | E | -128.4 | -165.9 | 97.0 | 0.431 | 0.0 |
HOH |
6.738 |
O |
O |
||
5njd | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | ARG | A:179 | A:179 | 85.0 | 0.378 | E | -147.4 | 169.0 | 85.0 | 0.378 | 0.0 | ||||||
ARG | C:179 | C:179 | 107.0 | 0.476 | E | -158.6 | 165.0 | NA | NA | NA | |||||||||||||
ARG | E:179 | E:179 | 83.0 | 0.369 | E | -161.2 | 162.6 | NA | NA | NA | |||||||||||||
ARG | G:179 | G:179 | 79.0 | 0.351 | E | -158.0 | 170.6 | NA | NA | NA | |||||||||||||
ARG | I:179 | I:179 | 86.0 | 0.382 | E | -156.4 | 161.8 | NA | NA | NA | |||||||||||||
ARG | K:179 | K:179 | 107.0 | 0.476 | E | -152.7 | 166.7 | NA | NA | NA | |||||||||||||
6wdq | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | ARG | A:159 | A:179 | 97.0 | 0.431 | E | -127.9 | -176.1 | 97.0 | 0.431 | 0.0 | ||||||
3duh | 1 | P29460 | 99.35 | 0.0 |
X-RAY |
2008-08-19 | ARG | A:159 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
ARG | B:159 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | |||||||||||||
1f42 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-13 | ARG | A:157 | A:157 | 94.0 | 0.418 | E | -129.0 | 165.6 | 94.0 | 0.418 | 0.0 |
HOH |
9.547 |
N |
O |
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1f45 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-20 | ARG | A:157 | NA:NA | DO | NA | DO | DO | DO | NA | NA | NA | ||||||
3hmx | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2010-06-09 | ARG | A:157 | A:157 | 149.0 | 0.662 | -82.4 | 80.9 | 149.0 | 0.662 | 0.0 |
HOH |
5.653 |
NH2 |
O |
|||
3qwr | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | ARG | A:157 | A:157 | 98.0 | NA | -115.1 | 360.0 | 98.0 | NA | NA | |||||||
5mj3 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ARG | A:157 | A:179 | 75.0 | 0.333 | E | -146.4 | 164.8 | 75.0 | 0.333 | 0.0 |
HOH |
6.264 |
HG3 |
O |
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5mj4 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ARG | A:157 | A:179 | 106.0 | NA | -146.6 | 360.0 | 106.0 | NA | NA | |||||||
6uib | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2020-07-15 | ARG | B:161 | B:157 | 142.0 | 0.631 | -144.6 | 148.0 | 142.0 | 0.631 | 0.0 |
HOH |
3.841 |
NH1 |
O |
|||
3d85 | 4 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | ARG | D:157 | D:157 | 91.0 | 0.404 | E | -147.2 | 164.6 | 91.0 | 0.404 | 0.0 |
HOH |
3.227 |
NH1 |
O |
||
3d87 | 2 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | ARG | B:157 | B:157 | 121.0 | 0.538 | E | -133.8 | 174.9 | 121.0 | 0.538 | 0.0 | ||||||
ARG | D:157 | D:157 | 138.0 | 0.613 | -47.7 | -153.6 | 138.0 | 0.613 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29460-f1 | 1 | P29460 | 100.0 | 0.0 | ARG | A:179 | A:179 | 114.0 | 0.507 | E | -120.3 | 133.1 |