Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 158750101 | . | C | A | CCDS4346.1:NM_002187.2:c.325Gat>Tat_NP_002178.2:p.109D>Y | Homo sapiens interleukin 12B (IL12B), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
4grw | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2014-02-19 | ASP | B:109 | B:87 | 144.0 | 0.96 | T | 60.1 | 34.1 | 142.0 | 0.947 | 0.013 |
H:None:0.013 |
HOH |
3.088 |
N |
O |
|
ASP | D:109 | D:87 | 153.0 | 1.0 | T | 62.9 | 32.2 | NA | NA | NA | |||||||||||||
5mxa | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-12-20 | ASP | B:109 | A:109 | 135.0 | 0.9 | T | 58.9 | 32.7 | 135.0 | 0.9 | 0.0 | ||||||
5mzv | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | ASP | A:109 | A:109 | 144.0 | 0.96 | T | 58.6 | 39.9 | 112.0 | 0.747 | 0.213 |
C:Q5VWK5:0.213 |
HOH |
4.295 |
HB2 |
O |
|
5njd | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2018-01-03 | ASP | A:109 | A:109 | 151.0 | 1.0 | T | 49.0 | 49.6 | 3.0 | 0.02 | 0.98 |
U:None:0.76 V:None:0.52 |
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ASP | C:109 | C:109 | 150.0 | 1.0 | T | 43.8 | 51.1 | NA | NA | NA | |||||||||||||
ASP | E:109 | E:109 | 161.0 | 1.0 | T | 56.6 | 35.7 | NA | NA | NA | |||||||||||||
ASP | G:109 | G:109 | 155.0 | 1.0 | T | 60.8 | 45.4 | NA | NA | NA | |||||||||||||
ASP | I:109 | I:109 | 148.0 | 0.987 | T | 58.4 | 44.1 | NA | NA | NA | |||||||||||||
ASP | K:109 | K:109 | 155.0 | 1.0 | T | 55.7 | 46.2 | NA | NA | NA | |||||||||||||
6wdq | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2021-02-24 | ASP | A:89 | A:109 | 145.0 | 0.967 | T | 55.5 | 41.7 | 105.0 | 0.7 | 0.267 |
C:Q5VWK5:0.267 |
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3duh | 1 | P29460 | 99.35 | 0.0 |
X-RAY |
2008-08-19 | ASP | A:89 | A:87 | 117.0 | 0.78 | S | -161.1 | 68.9 | 117.0 | 0.78 | 0.0 | ||||||
ASP | B:89 | B:87 | 169.0 | 1.0 | T | 54.9 | 50.1 | NA | NA | NA | |||||||||||||
1f42 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-13 | ASP | A:87 | A:87 | 170.0 | 1.0 | T | 58.2 | 31.2 | 170.0 | 1.0 | 0.0 | ||||||
1f45 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2001-06-20 | ASP | A:87 | A:87 | 165.0 | 1.0 | T | 64.7 | 21.9 | 165.0 | 1.0 | 0.0 |
HOH |
8.169 |
C |
O |
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3hmx | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2010-06-09 | ASP | A:87 | A:87 | 108.0 | 0.72 | S | -175.7 | 74.9 | 108.0 | 0.72 | 0.0 | ||||||
3qwr | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2012-02-01 | ASP | A:87 | A:87 | 172.0 | 1.0 | T | 52.5 | 35.8 | 172.0 | 1.0 | 0.0 | ||||||
5mj3 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:87 | A:109 | 151.0 | 1.0 | T | 56.7 | 44.8 | 151.0 | 1.0 | 0.0 |
PGE HOH |
5.116 7.884 |
C O |
O4 O |
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5mj4 | 1 | P29460 | 100.0 | 0.0 |
X-RAY |
2017-01-11 | ASP | A:87 | A:109 | 151.0 | 1.0 | T | 57.0 | 48.5 | 128.0 | 0.853 | 0.147 |
C:None:0.153 |
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6uib | 2 | P29460 | 100.0 | 0.0 |
X-RAY |
2020-07-15 | ASP | B:91 | B:87 | 175.0 | 1.0 | S | 58.4 | 41.6 | 175.0 | 1.0 | 0.0 | ||||||
3d85 | 4 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | ASP | D:87 | D:87 | 170.0 | 1.0 | T | 52.5 | 31.9 | 170.0 | 1.0 | 0.0 |
HOH |
2.922 |
O |
O |
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3d87 | 2 | P29460 | 99.67 | 0.0 |
X-RAY |
2008-09-02 | ASP | B:87 | B:87 | 172.0 | 1.0 | T | 43.4 | 45.7 | 172.0 | 1.0 | 0.0 | ||||||
ASP | D:87 | D:87 | 164.0 | 1.0 | T | 47.2 | 36.1 | 164.0 | 1.0 | 0.0 |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p29460-f1 | 1 | P29460 | 100.0 | 0.0 | ASP | A:109 | A:109 | 164.0 | 1.0 | T | 51.0 | 37.2 |