Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 224595 . A C CCDS3853.1:NM_004168.2:c.271Acc>Ccc_NP_004159.2:p.91T>P Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 THR A:59 A:91 11.0 0.079 E -159.0 131.3 11.0 0.079 0.0 FAD
HOH
 3.151
7.245
 CG2
OG1
 O2B
O
THR C:59 C:91 9.0 0.064 E -154.3 138.1 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 THR A:91 A:49 8.0 0.057 E -135.6 129.2 8.0 0.057 0.0 FAD
HOH
 2.841
9.447
 OG1
O
 O2B
O
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 THR A:91 A:49 8.0 0.057 E -149.6 128.9 8.0 0.057 0.0 FAD
 2.878
 OG1
 O2B
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 THR A:49 A:49 10.0 0.071 E -143.5 136.8 10.0 0.071 0.0 FAD
HOH
 2.663
6.776
 OG1
O
 O2B
O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 THR A:49 A:49 11.0 0.079 E -144.6 137.2 11.0 0.079 0.0 FAD
 2.783
 OG1
 O2B
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 9.0 0.064 E -146.4 137.0 9.0 0.064 0.0 FAD
 2.613
 OG1
 O2B
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 9.0 0.064 E -152.3 136.3 9.0 0.064 0.0 FAD
 2.344
 OG1
 O2B
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 7.0 0.05 E -141.6 138.3 7.0 0.05 0.0 FAD
 2.785
 OG1
 O2B
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 8.0 0.057 E -146.9 135.0 8.0 0.057 0.0 FAD
 2.259
 OG1
 O2B
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 9.0 0.064 E -152.1 131.8 9.0 0.064 0.0 FAD
 2.577
 OG1
 O2B
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 8.0 0.057 E -150.5 138.7 8.0 0.057 0.0 FAD
 2.324
 OG1
 O2B
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 10.0 0.071 E -147.7 134.9 10.0 0.071 0.0 FAD
 2.240
 OG1
 O2B
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 10.0 0.071 E -149.9 140.6 10.0 0.071 0.0 FAD
 2.216
 OG1
 O2B
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 10.0 0.071 E -148.5 138.8 10.0 0.071 0.0 FAD
 2.427
 OG1
 O2B
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 9.0 0.064 E -155.5 136.2 9.0 0.064 0.0 FAD
 2.672
 OG1
 O2B
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 10.0 0.071 E -143.3 138.3 10.0 0.071 0.0 FAD
 2.218
 OG1
 O2B
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 10.0 0.071 E -143.4 136.3 10.0 0.071 0.0 FAD
 2.667
 OG1
 O2B
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 9.0 0.064 E -150.2 134.6 9.0 0.064 0.0 FAD
 2.225
 OG1
 O2B
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 8.0 0.057 E -140.0 133.0 8.0 0.057 0.0 FAD
 2.309
 OG1
 O2B
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 10.0 0.071 E -151.6 133.4 10.0 0.071 0.0 FAD
 2.511
 OG1
 O2B
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 7.0 0.05 E -141.2 139.1 7.0 0.05 0.0 FAD
 2.358
 OG1
 O2B
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 THR A:49 A:49 9.0 0.064 E -144.8 133.9 9.0 0.064 0.0 FAD
 2.616
 OG1
 O2B
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 THR A:49 A:49 9.0 0.064 E -146.5 131.4 9.0 0.064 0.0 FAD
HOH
 2.537
6.775
 OG1
O
 O2B
O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 THR A:49 A:49 10.0 0.071 E -148.3 135.7 10.0 0.071 0.0 FAD
HOH
 2.380
8.717
 OG1
CG2
 O2B
O
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 THR A:48 A:48 6.0 0.043 E -142.2 148.0 6.0 0.043 0.0 FAD
HOH
 2.528
6.437
 OG1
O
 O2B
O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 THR A:48 A:48 7.0 0.05 E -141.4 148.0 7.0 0.05 0.0 FAD
HOH
 2.679
6.868
 OG1
O
 O2B
O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 THR A:48 A:48 10.0 0.071 E -138.7 137.8 10.0 0.071 0.0 FAD
UNL
UNL
UNL
UNL
UNL
HOH
 2.827
7.538
8.051
9.246
8.256
9.686
6.589
 OG1
O
C
O
O
CG2
O
 O2B
C
O12
O
O
O
O
THR E:48 N:48 9.0 0.064 E -140.9 135.1 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 THR A:48 A:48 9.0 0.064 E -143.5 138.8 9.0 0.064 0.0 FAD
HOH
 2.944
6.618
 OG1
O
 O2B
O
THR E:48 N:48 9.0 0.064 E -139.7 140.2 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 THR A:48 A:48 8.0 0.057 -141.3 153.8 8.0 0.057 0.0 FAD
HOH
 2.605
6.919
 OG1
O
 O2B
O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 THR A:48 A:48 10.0 0.071 E -140.8 139.6 10.0 0.071 0.0 AZI
FAD
HOH
 7.117
2.799
6.753
 CG2
OG1
O
 N3
O2B
O
THR E:48 N:48 9.0 0.064 E -140.6 139.0 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 THR A:48 A:48 8.0 0.057 E -139.1 142.2 8.0 0.057 0.0 FAD
UNL
UNL
UNL
UNL
HOH
 2.638
7.785
8.086
7.471
9.449
6.601
 OG1
C
CG2
OG1
O
O
 O2B
C3
N1
N3
N3
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 THR A:48 A:48 8.0 0.057 E -147.2 136.4 8.0 0.057 0.0 FAD
UNL
UNL
UNL
UNL
UNL
UNL
HOH
 2.561
7.596
8.592
9.456
6.903
9.580
7.869
6.377
 OG1
C
O
O
O
O
CG2
O
 O2B
C3
O
O
O
N3
S2
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 THR A:48 A:48 6.0 0.043 E -140.2 141.1 6.0 0.043 0.0 FAD
UNL
UNL
UNL
UNL
HOH
 2.905
7.690
7.370
9.415
9.430
6.673
 OG1
C
OG1
O
CG2
O
 O2B
C3
N3
N3
C1
O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 THR A:48 A:48 9.0 0.064 E -146.9 138.2 9.0 0.064 0.0 FAD
UNL
UNL
UNL
HOH
 2.699
7.762
7.731
9.622
7.289
 OG1
C
CG2
O
OG1
 O2B
C3
O1S
N3
O
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 THR A:48 A:48 9.0 0.064 E -141.9 133.8 9.0 0.064 0.0 FAD
UNL
UNL
HOH
 2.457
7.618
7.544
7.744
 OG1
C
CG2
OG1
 O2B
C3
C2
O
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 THR A:48 A:48 10.0 0.071 E -148.2 138.0 10.0 0.071 0.0 FAD
UNL
UNL
UNL
UNL
UNL
UNL
HOH
 2.387
7.484
7.609
9.914
7.878
8.947
9.368
7.603
 OG1
C
OG1
OG1
OG1
O
CG2
OG1
 O2B
C3
N3
O
O
N3
C2
O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 THR A:48 A:48 8.0 0.057 E -141.7 139.8 8.0 0.057 0.0 FAD
UNL
UNL
UNL
UNL
HOH
 2.799
7.727
7.301
9.565
9.411
6.687
 OG1
C
OG1
OG1
CG2
O
 O2B
C3
N3
N1
C2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 THR A:91 A:91 7.0 0.05 E -143.6 133.0