Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 225675 | . | G | A | CCDS3853.1:NM_004168.2:c.454Gag>Aag_NP_004159.2:p.152E>K | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | GLU | A:120 | A:152 | 45.0 | 0.237 | H | -67.1 | -38.5 | 45.0 | 0.237 | 0.0 |
HOH |
6.707 |
OE2 |
O |
||
GLU | C:120 | C:152 | 45.0 | 0.237 | H | -64.0 | -37.7 | NA | NA | NA | |||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | GLU | A:152 | A:110 | 35.0 | 0.184 | H | -53.9 | -41.1 | 22.0 | 0.116 | 0.068 |
B:Q007T0:0.068 |
HOH |
3.523 |
CB |
O |
|
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | GLU | A:152 | A:110 | 32.0 | 0.168 | H | -61.7 | -39.0 | 17.0 | 0.089 | 0.079 |
B:Q007T0:0.079 |
|||||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLU | A:110 | A:110 | 34.0 | 0.179 | H | -64.5 | -40.9 | 21.0 | 0.111 | 0.068 |
B:Q007T0:0.068 |
HOH |
2.367 |
N |
O |
|
1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLU | A:110 | A:110 | 36.0 | 0.189 | H | -64.3 | -40.6 | 23.0 | 0.121 | 0.068 |
B:None:0.068 |
|||||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 37.0 | 0.195 | H | -52.0 | -41.9 | 24.0 | 0.126 | 0.069 |
B:Q007T0:0.068 |
|||||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 37.0 | 0.195 | H | -54.5 | -45.6 | 24.0 | 0.126 | 0.069 |
B:Q007T0:0.068 |
|||||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 36.0 | 0.189 | H | -49.0 | -45.2 | 22.0 | 0.116 | 0.073 |
B:Q007T0:0.074 |
|||||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 42.0 | 0.221 | H | -53.7 | -43.9 | 28.0 | 0.147 | 0.074 |
B:Q007T0:0.074 |
|||||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 36.0 | 0.189 | H | -59.8 | -42.3 | 22.0 | 0.116 | 0.073 |
B:Q007T0:0.074 |
|||||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 36.0 | 0.189 | H | -61.0 | -41.4 | 22.0 | 0.116 | 0.073 |
B:Q007T0:0.074 |
|||||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 40.0 | 0.211 | H | -53.7 | -50.9 | 25.0 | 0.132 | 0.079 |
B:Q007T0:0.079 |
|||||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 35.0 | 0.184 | H | -62.8 | -47.3 | 20.0 | 0.105 | 0.079 |
B:Q007T0:0.079 |
|||||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 34.0 | 0.179 | H | -53.1 | -43.3 | 21.0 | 0.111 | 0.068 |
B:Q007T0:0.068 |
|||||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 37.0 | 0.195 | H | -63.7 | -39.3 | 23.0 | 0.121 | 0.074 |
B:Q007T0:0.074 |
|||||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 35.0 | 0.184 | H | -59.7 | -41.4 | 20.0 | 0.105 | 0.079 |
B:Q007T0:0.079 |
|||||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 38.0 | 0.2 | H | -54.6 | -49.7 | 26.0 | 0.137 | 0.063 |
B:Q007T0:0.063 |
|||||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 41.0 | 0.216 | H | -62.6 | -47.0 | 23.0 | 0.121 | 0.095 |
B:Q007T0:0.095 |
|||||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 42.0 | 0.221 | H | -63.6 | -44.6 | 25.0 | 0.132 | 0.089 |
B:Q007T0:0.089 |
|||||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 34.0 | 0.179 | H | -62.7 | -36.9 | 20.0 | 0.105 | 0.074 |
B:Q007T0:0.074 |
|||||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 37.0 | 0.195 | H | -62.0 | -38.2 | 25.0 | 0.132 | 0.063 |
B:Q007T0:0.063 |
|||||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLU | A:110 | A:110 | 38.0 | 0.2 | H | -59.4 | -40.5 | 19.0 | 0.1 | 0.1 |
B:Q007T0:0.1 |
|||||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLU | A:110 | A:110 | 35.0 | 0.184 | H | -62.1 | -45.3 | 22.0 | 0.116 | 0.068 |
B:Q007T0:0.068 |
HOH |
2.950 |
OE2 |
O |
|
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLU | A:110 | A:110 | 38.0 | 0.2 | H | -54.4 | -44.4 | 27.0 | 0.142 | 0.058 |
B:Q007T0:0.058 |
HOH |
7.171 |
N |
O |
|
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLU | A:109 | A:109 | 39.0 | 0.205 | H | -58.9 | -45.4 | 30.0 | 0.158 | 0.047 |
B:Q9YHT2:0.047 |
HOH |
2.464 |
OE1 |
O |
|
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLU | A:109 | A:109 | 37.0 | 0.195 | H | -66.7 | -36.4 | 28.0 | 0.147 | 0.048 |
B:3851612:0.047 |
HOH |
2.580 |
OE2 |
O |
|
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLU | A:109 | A:109 | 44.0 | 0.232 | H | -51.3 | -51.2 | 26.0 | 0.137 | 0.095 |
B:Q9YHT2:0.095 |
UNL UNL UNL HOH |
9.392 2.336 8.702 2.562 |
OE2 OE2 N OE1 |
O3 O O O |
|
GLU | E:109 | N:109 | 41.0 | 0.216 | H | -53.6 | -50.4 | NA | NA | NA | |||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLU | A:109 | A:109 | 41.0 | 0.216 | H | -58.5 | -43.6 | 29.0 | 0.153 | 0.063 |
B:Q9YHT2:0.063 |
HOH |
2.554 |
OE1 |
O |
|
GLU | E:109 | N:109 | 45.0 | 0.237 | H | -55.8 | -43.7 | NA | NA | NA | |||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLU | A:109 | A:109 | 42.0 | 0.221 | H | -58.8 | -40.7 | 35.0 | 0.184 | 0.037 |
B:Q9YHT2:0.037 |
HOH |
2.610 |
OE1 |
O |
|
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | GLU | A:109 | A:109 | 41.0 | 0.216 | H | -54.3 | -48.3 | 26.0 | 0.137 | 0.079 |
B:Q9YHT2:0.079 |
HOH |
2.618 |
OE1 |
O |
|
GLU | E:109 | N:109 | 44.0 | 0.232 | H | -54.1 | -48.0 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:109 | A:109 | 39.0 | 0.205 | H | -54.1 | -44.8 | 27.0 | 0.142 | 0.063 |
B:Q9YHT2:0.063 |
UNL UNL UNL HOH |
6.499 4.781 8.594 2.720 |
OE2 OE2 N OE1 |
O O O O |
|
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:109 | A:109 | 42.0 | 0.221 | H | -63.5 | -36.9 | 26.0 | 0.137 | 0.084 |
B:Q9YHT2:0.084 |
UNL UNL HOH |
5.571 9.696 2.468 |
OE2 OE2 OE1 |
N1 C O |
|
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:109 | A:109 | 38.0 | 0.2 | H | -55.4 | -39.8 | 29.0 | 0.153 | 0.047 |
B:Q9YHT2:0.047 |
UNL UNL HOH |
5.042 7.071 2.430 |
OE2 O OE1 |
O O O |
|
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | GLU | A:109 | A:109 | 42.0 | 0.221 | H | -55.5 | -45.9 | 25.0 | 0.132 | 0.089 |
B:Q9YHT2:0.089 |
UNL HOH |
6.908 2.840 |
O OE1 |
N2 O |
|
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:109 | A:109 | 42.0 | 0.221 | H | -62.4 | -46.7 | 27.0 | 0.142 | 0.079 |
B:Q9YHT2:0.079 |
UNL HOH |
6.986 3.505 |
OE2 OE1 |
O O |
|
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:109 | A:109 | 37.0 | 0.195 | H | -63.4 | -40.4 | 24.0 | 0.126 | 0.069 |
B:Q9YHT2:0.068 |
HOH |
2.570 |
OE1 |
O |
|
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLU | A:109 | A:109 | 39.0 | 0.205 | H | -55.1 | -39.8 | 27.0 | 0.142 | 0.063 |
B:Q9YHT2:0.063 |
UNL UNL HOH |
4.849 7.035 2.553 |
OE2 O OE1 |
O O O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | GLU | A:152 | A:152 | 32.0 | 0.168 | H | -58.9 | -45.4 |