Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 226009 . T A CCDS3853.1:NM_004168.2:c.468taT>taA_NP_004159.2:p.156Y>* Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 TYR A:124 A:156 29.0 0.126 H -73.6 -21.8 29.0 0.126 0.0 HOH
 6.302
 OH
 O
TYR C:124 C:156 34.0 0.148 H -68.6 -35.7 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 TYR A:156 A:114 38.0 0.165 T -80.8 -29.8 9.0 0.039 0.126 B:Q007T0:0.126
 HOH
 5.442
 N
 O
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 TYR A:156 A:114 36.0 0.157 T -78.3 -6.8 4.0 0.017 0.14 B:Q007T0:0.139
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 TYR A:114 A:114 40.0 0.174 H -76.8 -18.7 11.0 0.048 0.126 B:Q007T0:0.126
 HOH
 2.267
 O
 O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 TYR A:114 A:114 39.0 0.17 H -78.9 -21.6 11.0 0.048 0.122 B:None:0.122
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 40.0 0.174 H -71.7 -23.7 10.0 0.043 0.131 B:Q007T0:0.13
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 36.0 0.157 H -69.3 -25.6 5.0 0.022 0.135 B:Q007T0:0.135
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 39.0 0.17 H -71.0 -31.2 7.0 0.03 0.14 B:Q007T0:0.139
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 48.0 0.209 H -70.0 -36.9 14.0 0.061 0.148 B:Q007T0:0.148
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 47.0 0.204 H -65.3 -30.7 8.0 0.035 0.169 B:Q007T0:0.17
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 40.0 0.174 T -77.3 -29.4 7.0 0.03 0.144 B:Q007T0:0.143
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 32.0 0.139 H -68.1 -34.0 6.0 0.026 0.113 B:Q007T0:0.113
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 38.0 0.165 H -70.6 -35.9 9.0 0.039 0.126 B:Q007T0:0.126
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 47.0 0.204 H -72.7 -28.5 12.0 0.052 0.152 B:Q007T0:0.152
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 43.0 0.187 H -76.9 -29.0 10.0 0.043 0.144 B:Q007T0:0.143
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 41.0 0.178 H -72.1 -25.6 8.0 0.035 0.143 B:Q007T0:0.143
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 34.0 0.148 H -69.9 -27.0 6.0 0.026 0.122 B:Q007T0:0.122
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 32.0 0.139 H -77.1 -28.0 6.0 0.026 0.113 B:Q007T0:0.113
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 34.0 0.148 H -64.2 -28.3 6.0 0.026 0.122 B:Q007T0:0.122
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 41.0 0.178 H -67.2 -31.9 10.0 0.043 0.135 B:Q007T0:0.135
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 46.0 0.2 H -77.4 -30.8 11.0 0.048 0.152 B:Q007T0:0.152
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:114 A:114 45.0 0.196 T -82.2 -18.7 6.0 0.026 0.17 B:Q007T0:0.17
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 TYR A:114 A:114 39.0 0.17 H -63.5 -28.5 11.0 0.048 0.122 B:Q007T0:0.122
 HOH
 4.251
 O
 O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 TYR A:114 A:114 43.0 0.187 H -72.6 -31.1 12.0 0.052 0.135 B:Q007T0:0.135
 HOH
 7.450
 OH
 O
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 TYR A:113 A:113 38.0 0.165 H -73.5 -18.6 8.0 0.035 0.13 B:Q9YHT2:0.13
 HOH
 2.431
 OH
 O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 TYR A:113 A:113 37.0 0.161 T -83.0 -11.8 10.0 0.043 0.118 B:3851612:0.117
 HOH
 3.873
 O
 O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 TYR A:113 A:113 38.0 0.165 T -73.2 -10.5 7.0 0.03 0.135 B:Q9YHT2:0.135
 UNL
UNL
UNL
UNL
HOH
 4.211
7.922
6.486
7.351
2.367
 CE1
CE1
O
O
OH
 O
N1
O
O
O
TYR E:113 N:113 37.0 0.161 T -77.2 -11.3 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 TYR A:113 A:113 40.0 0.174 T -84.0 -5.9 9.0 0.039 0.135 B:Q9YHT2:0.135
 HOH
 2.629
 O
 O
TYR E:113 N:113 39.0 0.17 T -84.5 -6.4 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 TYR A:113 A:113 41.0 0.178 H -81.5 -36.8 12.0 0.052 0.126 B:Q9YHT2:0.126
 HOH
 3.038
 CE2
 O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 TYR A:113 A:113 39.0 0.17 T -84.2 -9.3 8.0 0.035 0.135 B:Q9YHT2:0.135
 HOH
 2.513
 OH
 O
TYR E:113 N:113 40.0 0.174 T -85.3 -9.8 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:113 A:113 36.0 0.157 H -70.0 -28.6 5.0 0.022 0.135 B:Q9YHT2:0.135
 UNL
UNL
HOH
 7.179
6.409
2.579
 OH
OH
OH
 O
O
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:113 A:113 38.0 0.165 H -72.3 -23.7 4.0 0.017 0.148 B:Q9YHT2:0.148
 UNL
HOH
 6.068
2.436
 OH
OH
 N1
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:113 A:113 39.0 0.17 H -69.4 -22.9 6.0 0.026 0.144 B:Q9YHT2:0.143
 UNL
UNL
HOH
 6.564
5.356
2.319
 OH
N
OH
 O
O
O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 TYR A:113 A:113 34.0 0.148 T -66.6 -15.5 2.0 0.009 0.139 B:Q9YHT2:0.139
 UNL
HOH
 4.699
3.426
 CA
O
 N3
O
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:113 A:113 35.0 0.152 T -73.5 -11.2 2.0 0.009 0.143 B:Q9YHT2:0.143
 UNL
HOH
 7.960
3.352
 OH
O
 O
O
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:113 A:113 34.0 0.148 H -72.8 -16.3 4.0 0.017 0.131 B:Q9YHT2:0.13
 HOH
 2.743
 OH
 O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:113 A:113 37.0 0.161 H -70.8 -19.7 4.0 0.017 0.144 B:Q9YHT2:0.143
 UNL
UNL
HOH
 6.502
5.253
2.360
 OH
N
OH
 O
O
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 TYR A:156 A:156 44.0 0.191 T -77.8 -6.2