Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 226067 | . | C | A | CCDS3853.1:NM_004168.2:c.526Cag>Aag_NP_004159.2:p.176Q>K | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | GLN | A:144 | A:176 | 14.0 | 0.078 | -100.5 | 133.1 | 14.0 | 0.078 | 0.0 |
FAD OAA HOH |
9.605 9.505 6.991 |
NE2 NE2 NE2 |
O2 O5 O |
|||
GLN | C:144 | C:176 | 5.0 | 0.028 | -93.1 | 130.8 | NA | NA | NA | ||||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | GLN | A:176 | A:134 | 3.0 | 0.017 | E | -112.9 | 146.7 | 3.0 | 0.017 | 0.0 |
FAD |
9.457 |
NE2 |
O2 |
||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | GLN | A:176 | A:134 | 6.0 | 0.033 | E | -133.8 | 124.0 | 6.0 | 0.033 | 0.0 |
FAD |
9.902 |
NE2 |
O2 |
||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLN | A:134 | A:134 | 3.0 | 0.017 | E | -138.6 | 116.4 | 3.0 | 0.017 | 0.0 |
FAD HOH |
8.901 3.174 |
NE2 N |
O2 O |
||
1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLN | A:134 | A:134 | 5.0 | 0.028 | E | -136.2 | 114.3 | 5.0 | 0.028 | 0.0 |
FAD 3NP |
8.675 9.063 |
NE2 NE2 |
O2 C2 |
||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 6.0 | 0.033 | E | -107.2 | 151.0 | 6.0 | 0.033 | 0.0 |
FAD MLI |
9.629 9.868 |
OE1 NE2 |
O2 O8 |
||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 3.0 | 0.017 | -104.8 | 142.1 | 3.0 | 0.017 | 0.0 |
FAD MLI |
9.720 9.385 |
OE1 NE2 |
O2 O7 |
|||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 4.0 | 0.022 | E | -104.3 | 148.5 | 4.0 | 0.022 | 0.0 |
FAD MLI |
9.499 9.785 |
OE1 NE2 |
O2 C1 |
||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 4.0 | 0.022 | E | -101.4 | 141.1 | 4.0 | 0.022 | 0.0 |
FAD |
9.826 |
NE2 |
O2 |
||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 3.0 | 0.017 | E | -117.4 | 133.0 | 3.0 | 0.017 | 0.0 |
FAD MLI |
9.575 9.161 |
NE2 NE2 |
O2 C1 |
||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 2.0 | 0.011 | -127.1 | 131.4 | 2.0 | 0.011 | 0.0 |
FAD MLI |
9.443 8.385 |
NE2 NE2 |
O2 O9 |
|||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 3.0 | 0.017 | E | -106.1 | 147.3 | 3.0 | 0.017 | 0.0 |
FAD |
9.896 |
NE2 |
O2 |
||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 3.0 | 0.017 | E | -123.0 | 139.5 | 3.0 | 0.017 | 0.0 |
FAD |
9.611 |
NE2 |
O2 |
||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 5.0 | 0.028 | E | -104.9 | 135.7 | 5.0 | 0.028 | 0.0 | ||||||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 5.0 | 0.028 | E | -95.9 | 147.6 | 5.0 | 0.028 | 0.0 |
MLI |
9.902 |
NE2 |
O6 |
||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 5.0 | 0.028 | E | -107.3 | 132.2 | 5.0 | 0.028 | 0.0 |
FAD MLI |
9.630 9.034 |
NE2 NE2 |
O2 O7 |
||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 5.0 | 0.028 | E | -110.2 | 138.5 | 5.0 | 0.028 | 0.0 |
FAD MLI |
9.688 9.575 |
NE2 NE2 |
O2 O8 |
||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 1.0 | 0.006 | -79.9 | 142.3 | 1.0 | 0.006 | 0.0 |
FAD |
9.725 |
NE2 |
O2 |
|||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 5.0 | 0.028 | -111.9 | 133.1 | 5.0 | 0.028 | 0.0 |
FAD MLI |
9.496 8.896 |
NE2 NE2 |
O2 O9 |
|||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 4.0 | 0.022 | E | -110.8 | 132.9 | 4.0 | 0.022 | 0.0 |
FAD |
9.114 |
NE2 |
O2 |
||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 6.0 | 0.033 | -120.3 | 130.2 | 6.0 | 0.033 | 0.0 |
FAD HOH |
9.317 9.510 |
NE2 NE2 |
O2 O |
|||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:134 | A:134 | 5.0 | 0.028 | E | -103.9 | 150.5 | 5.0 | 0.028 | 0.0 | ||||||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLN | A:134 | A:134 | 4.0 | 0.022 | E | -123.7 | 135.1 | 4.0 | 0.022 | 0.0 |
FAD OAA HOH |
9.181 8.437 5.479 |
NE2 NE2 C |
O2 O1 O |
||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLN | A:134 | A:134 | 6.0 | 0.033 | E | -130.8 | 132.1 | 6.0 | 0.033 | 0.0 |
FAD OAA HOH |
9.265 8.615 6.013 |
NE2 NE2 O |
O2 O1 O |
||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLN | A:133 | A:133 | 5.0 | 0.028 | -123.3 | 140.3 | 5.0 | 0.028 | 0.0 |
FAD TEO HOH |
9.208 8.759 2.922 |
NE2 NE2 NE2 |
O2 O4B O |
|||
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLN | A:133 | A:133 | 3.0 | 0.017 | -104.6 | 132.8 | 3.0 | 0.017 | 0.0 |
FAD 3NP HOH |
9.215 9.691 2.985 |
NE2 NE2 CG |
O2 C2 O |
|||
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLN | A:133 | A:133 | 4.0 | 0.022 | -118.8 | 136.4 | 4.0 | 0.022 | 0.0 |
FAD Y3P UNL UNL HOH |
9.336 8.732 3.019 7.447 2.769 |
NE2 NE2 N O NE2 |
O2 HC3 OAA O O |
|||
GLN | E:133 | N:133 | 4.0 | 0.022 | -120.5 | 133.0 | NA | NA | NA | ||||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLN | A:133 | A:133 | 5.0 | 0.028 | -115.9 | 134.4 | 5.0 | 0.028 | 0.0 |
FAD TEO HOH |
9.284 8.762 2.895 |
NE2 NE2 O |
O2 O4A O |
|||
GLN | E:133 | N:133 | 5.0 | 0.028 | -115.6 | 136.1 | NA | NA | NA | ||||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLN | A:133 | A:133 | 7.0 | 0.039 | -138.5 | 120.6 | 7.0 | 0.039 | 0.0 |
FAD MLI HOH |
9.365 9.235 2.993 |
NE2 NE2 NE2 |
O2 O9 O |
|||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | GLN | A:133 | A:133 | 4.0 | 0.022 | E | -116.1 | 133.4 | 4.0 | 0.022 | 0.0 |
FAD OAA HOH |
9.335 8.788 2.753 |
NE2 NE2 NE2 |
O2 O2 O |
||
GLN | E:133 | N:133 | 4.0 | 0.022 | E | -116.4 | 132.7 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:133 | A:133 | 4.0 | 0.022 | -124.7 | 130.4 | 4.0 | 0.022 | 0.0 |
FAD OAA HOH |
9.513 8.956 2.963 |
NE2 NE2 NE2 |
O2 O2 O |
|||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:133 | A:133 | 4.0 | 0.022 | -121.5 | 141.5 | 4.0 | 0.022 | 0.0 |
FAD OAA UNL HOH |
9.368 8.731 6.177 2.950 |
NE2 NE2 C NE2 |
O2 O2 O O |
|||
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:133 | A:133 | 4.0 | 0.022 | -117.9 | 137.0 | 4.0 | 0.022 | 0.0 |
FAD Y3P HOH |
9.123 8.589 2.973 |
NE2 NE2 NE2 |
O2 HC3 O |
|||
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | GLN | A:133 | A:133 | 5.0 | 0.028 | E | -132.0 | 126.9 | 5.0 | 0.028 | 0.0 |
FAD OAA HOH |
9.355 8.862 3.013 |
NE2 NE2 NE2 |
O2 O2 O |
||
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:133 | A:133 | 3.0 | 0.017 | -138.7 | 134.9 | 3.0 | 0.017 | 0.0 |
FAD OAA HOH |
9.505 8.818 2.792 |
NE2 NE2 NE2 |
O2 O2 O |
|||
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:133 | A:133 | 4.0 | 0.022 | -113.4 | 127.4 | 4.0 | 0.022 | 0.0 |
FAD OAA UNL UNL HOH |
9.064 8.850 2.975 9.863 2.823 |
NE2 NE2 NE2 O NE2 |
O2 O2 O O O |
|||
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:133 | A:133 | 4.0 | 0.022 | -124.4 | 134.7 | 4.0 | 0.022 | 0.0 |
FAD OAA HOH |
9.253 8.684 3.016 |
NE2 NE2 NE2 |
O2 O2 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | GLN | A:176 | A:176 | 5.0 | 0.028 | -112.3 | 130.6 |