Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 226156 | . | T | A | CCDS3853.1:NM_004168.2:c.615taT>taA_NP_004159.2:p.205Y>* | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
|---|---|---|---|---|---|---|---|
|
|
|
|
|
PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | TYR | A:173 | A:205 | 38.0 | 0.165 | H | -68.1 | -36.2 | 11.0 | 0.048 | 0.117 |
B:Q9NX18:0.117 |
FAD HOH |
9.590 9.928 |
CD1 OH |
O3B O |
|
| TYR | C:173 | C:205 | 41.0 | 0.178 | H | -68.7 | -39.6 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | TYR | A:205 | A:163 | 50.0 | 0.217 | H | -44.5 | -49.6 | 19.0 | 0.083 | 0.134 |
B:Q007T0:0.135 |
FAD HOH |
9.572 9.854 |
CD1 OH |
O3B O |
|
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | TYR | A:205 | A:163 | 48.0 | 0.209 | H | -61.0 | -49.1 | 16.0 | 0.07 | 0.139 |
B:Q007T0:0.139 |
FAD |
9.609 |
CD1 |
O3B |
|
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | TYR | A:163 | A:163 | 49.0 | 0.213 | H | -59.5 | -50.1 | 18.0 | 0.078 | 0.135 |
B:Q007T0:0.135 |
FAD HOH |
9.500 4.917 |
CD1 OH |
O3B O |
|
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | TYR | A:163 | A:163 | 51.0 | 0.222 | H | -59.8 | -52.9 | 19.0 | 0.083 | 0.139 |
B:None:0.139 |
FAD |
9.593 |
CD1 |
O3B |
|
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 52.0 | 0.226 | H | -69.0 | -42.0 | 21.0 | 0.091 | 0.135 |
B:Q007T0:0.135 |
FAD |
9.613 |
CD1 |
O3B |
|
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 54.0 | 0.235 | H | -60.4 | -42.8 | 20.0 | 0.087 | 0.148 |
B:Q007T0:0.148 |
FAD |
9.753 |
CD1 |
O3B |
|
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 57.0 | 0.248 | H | -61.9 | -46.4 | 20.0 | 0.087 | 0.161 |
B:Q007T0:0.161 |
FAD |
9.555 |
CD1 |
O3B |
|
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 54.0 | 0.235 | H | -62.7 | -49.4 | 17.0 | 0.074 | 0.161 |
B:Q007T0:0.161 |
FAD |
9.540 |
CD1 |
O3B |
|
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 53.0 | 0.23 | H | -56.8 | -43.9 | 22.0 | 0.096 | 0.134 |
B:Q007T0:0.135 |
FAD |
9.727 |
CD1 |
O3B |
|
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 56.0 | 0.243 | H | -59.0 | -44.1 | 20.0 | 0.087 | 0.156 |
B:Q007T0:0.157 |
FAD |
9.607 |
CD1 |
O3B |
|
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 54.0 | 0.235 | H | -70.6 | -47.3 | 18.0 | 0.078 | 0.157 |
B:Q007T0:0.157 |
FAD |
9.654 |
CD1 |
O3B |
|
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 48.0 | 0.209 | H | -69.0 | -43.9 | 16.0 | 0.07 | 0.139 |
B:Q007T0:0.139 |
FAD |
9.744 |
CD1 |
O3B |
|
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 57.0 | 0.248 | H | -64.8 | -44.5 | 17.0 | 0.074 | 0.174 |
B:Q007T0:0.174 |
FAD |
9.717 |
CD1 |
O3B |
|
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 57.0 | 0.248 | H | -68.6 | -51.7 | 16.0 | 0.07 | 0.178 |
B:Q007T0:0.174 C:D0VWV4:0.004 |
|||||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 52.0 | 0.226 | H | -68.7 | -48.9 | 16.0 | 0.07 | 0.156 |
B:Q007T0:0.157 |
FAD |
9.282 |
CD1 |
O3B |
|
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 54.0 | 0.235 | H | -65.5 | -43.4 | 18.0 | 0.078 | 0.157 |
B:Q007T0:0.157 |
FAD |
9.609 |
CD1 |
O3B |
|
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 56.0 | 0.243 | H | -70.3 | -40.3 | 16.0 | 0.07 | 0.173 |
B:Q007T0:0.174 |
FAD |
9.774 |
CD1 |
O3B |
|
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 53.0 | 0.23 | H | -62.4 | -46.0 | 16.0 | 0.07 | 0.16 |
B:Q007T0:0.161 |
FAD |
9.231 |
CD1 |
O3B |
|
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 51.0 | 0.222 | H | -53.4 | -54.8 | 18.0 | 0.078 | 0.144 |
B:Q007T0:0.143 |
FAD |
9.292 |
CD1 |
O3B |
|
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 55.0 | 0.239 | H | -57.3 | -43.0 | 20.0 | 0.087 | 0.152 |
B:Q007T0:0.152 |
FAD |
9.609 |
CD1 |
O3B |
|
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | TYR | A:163 | A:163 | 47.0 | 0.204 | H | -65.3 | -49.1 | 16.0 | 0.07 | 0.134 |
B:Q007T0:0.135 |
FAD |
9.971 |
CD1 |
O3B |
|
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | TYR | A:163 | A:163 | 58.0 | 0.252 | H | -58.6 | -45.8 | 20.0 | 0.087 | 0.165 |
B:Q007T0:0.157 C:D0VWV4:0.009 |
FAD HOH |
9.875 5.629 |
CD1 C |
O3B O |
|
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | TYR | A:163 | A:163 | 51.0 | 0.222 | H | -56.9 | -49.3 | 17.0 | 0.074 | 0.148 |
B:Q007T0:0.148 |
FAD HOH |
9.805 4.395 |
CD1 OH |
O3B O |
|
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | TYR | A:162 | A:162 | 54.0 | 0.235 | H | -66.0 | -40.5 | 4.0 | 0.017 | 0.218 |
B:Q9YHT2:0.217 |
FAD UNL HOH |
9.510 6.954 2.445 |
CD1 OH OH |
O3B O1 O |
|
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | TYR | A:162 | A:162 | 54.0 | 0.235 | H | -64.6 | -43.7 | 5.0 | 0.022 | 0.213 |
B:3851612:0.213 C:None:0.004 |
FAD HOH |
9.252 3.180 |
CD1 OH |
O3B O |
|
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | TYR | A:162 | A:162 | 56.0 | 0.243 | H | -65.2 | -46.4 | 22.0 | 0.096 | 0.147 |
B:Q9YHT2:0.148 |
FAD UNL UNL UNL UNL UNL UNL UNL HOH |
9.889 5.992 8.346 8.979 8.370 7.518 8.522 4.355 2.939 |
CD1 OH OH OH N C OH OH OH |
O3B C O O O O O O O |
|
| TYR | E:162 | N:162 | 56.0 | 0.243 | H | -65.7 | -44.8 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | TYR | A:162 | A:162 | 55.0 | 0.239 | H | -62.5 | -48.4 | 20.0 | 0.087 | 0.152 |
B:Q9YHT2:0.152 |
FAD HOH |
9.660 2.546 |
CD1 OH |
O3B O |
|
| TYR | E:162 | N:162 | 56.0 | 0.243 | H | -60.9 | -48.2 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | TYR | A:162 | A:162 | 54.0 | 0.235 | H | -59.6 | -39.5 | 21.0 | 0.091 | 0.144 |
B:Q9YHT2:0.143 |
FAD UNL HOH |
9.425 3.873 3.776 |
CD1 OH CD2 |
O3B O1 O |
|
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | TYR | A:162 | A:162 | 56.0 | 0.243 | H | -64.8 | -42.6 | 20.0 | 0.087 | 0.156 |
B:Q9YHT2:0.157 |
AZI FAD HOH |
9.130 9.688 2.645 |
OH CD1 OH |
N3 O3B O |
|
| TYR | E:162 | N:162 | 56.0 | 0.243 | H | -65.5 | -41.6 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:162 | A:162 | 54.0 | 0.235 | H | -63.0 | -47.4 | 19.0 | 0.083 | 0.152 |
B:Q9YHT2:0.152 |
FAD UNL UNL HOH |
9.462 3.196 9.234 3.749 |
CD1 OH OH CD2 |
O3B N1 N3 O |
|
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:162 | A:162 | 56.0 | 0.243 | H | -69.5 | -38.6 | 21.0 | 0.091 | 0.152 |
B:Q9YHT2:0.152 |
FAD UNL UNL HOH |
9.659 9.557 3.493 3.642 |
CD1 OH OH CD2 |
O3B N3 C1 O |
|
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:162 | A:162 | 54.0 | 0.235 | H | -67.2 | -42.4 | 18.0 | 0.078 | 0.157 |
B:Q9YHT2:0.157 |
FAD UNL UNL HOH |
9.610 9.485 3.684 3.716 |
CD1 OH OH CD2 |
O3B N3 C1 O |
|
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | TYR | A:162 | A:162 | 54.0 | 0.235 | H | -63.1 | -48.1 | 21.0 | 0.091 | 0.144 |
B:Q9YHT2:0.143 |
FAD UNL UNL HOH |
9.698 3.194 9.511 3.654 |
CD1 OH OH CD2 |
O3B C2 N3 O |
|
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:162 | A:162 | 54.0 | 0.235 | H | -62.8 | -42.4 | 21.0 | 0.091 | 0.144 |
B:Q9YHT2:0.143 |
FAD UNL HOH |
9.562 3.150 3.689 |
CD1 OH CD2 |
O3B C2 O |
|
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:162 | A:162 | 50.0 | 0.217 | H | -64.9 | -46.9 | 18.0 | 0.078 | 0.139 |
B:Q9YHT2:0.139 |
FAD UNL UNL HOH |
9.553 9.464 3.363 6.842 |
CD1 OH OH OH |
O3B N3 C1 O |
|
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | TYR | A:162 | A:162 | 54.0 | 0.235 | H | -62.7 | -45.2 | 17.0 | 0.074 | 0.161 |
B:Q9YHT2:0.157 C:D0VWW3:0.004 |
FAD UNL UNL HOH |
9.587 9.747 3.583 3.687 |
CD1 OH OH CD2 |
O3B N3 C1 O |
|
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | TYR | A:205 | A:205 | 52.0 | 0.226 | H | -63.4 | -48.3 | |