Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 228311 . T A CCDS3853.1:NM_004168.2:c.633taT>taA_NP_004159.2:p.211Y>* Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 TYR A:179 A:211 91.0 0.396 T -105.3 24.3 91.0 0.396 0.0 HOH
 8.268
 CE2
 O
TYR C:179 C:211 81.0 0.352 T -95.9 23.8 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 TYR A:211 A:169 64.0 0.278 S -142.1 166.4 58.0 0.252 0.026 B:Q007T0:0.026
 HOH
 9.325
 OH
 O
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 TYR A:211 A:169 60.0 0.261 T -130.7 172.7 56.0 0.243 0.018 B:Q007T0:0.017
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 TYR A:169 A:169 60.0 0.261 S -117.2 172.2 55.0 0.239 0.022 B:Q007T0:0.022
 HOH
 5.373
 O
 O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 TYR A:169 A:169 60.0 0.261 S -115.2 176.4 55.0 0.239 0.022 B:None:0.022
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 55.0 0.239 S -117.0 162.2 52.0 0.226 0.013 B:Q007T0:0.013
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 52.0 0.226 S -109.3 165.6 48.0 0.209 0.017 B:Q007T0:0.017
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 57.0 0.248 S -125.2 156.2 56.0 0.243 0.005 B:Q007T0:0.004
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 58.0 0.252 S -120.9 167.9 52.0 0.226 0.026 B:Q007T0:0.026
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 51.0 0.222 S -108.7 169.0 47.0 0.204 0.018 B:Q007T0:0.017
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 57.0 0.248 S -138.0 161.5 55.0 0.239 0.009 B:Q007T0:0.009
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 50.0 0.217 S -113.4 150.1 47.0 0.204 0.013 B:Q007T0:0.013
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 51.0 0.222 S -114.2 154.5 51.0 0.222 0.0
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 60.0 0.261 S -129.1 161.2 56.0 0.243 0.018 B:Q007T0:0.013
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 61.0 0.265 S -122.1 156.8 57.0 0.248 0.017 B:Q007T0:0.017
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 53.0 0.23 S -116.7 158.7 50.0 0.217 0.013 B:Q007T0:0.013
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 53.0 0.23 S -118.0 166.6 50.0 0.217 0.013 B:Q007T0:0.013
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 52.0 0.226 S -110.6 153.1 52.0 0.226 0.0
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 59.0 0.257 T -117.4 166.8 55.0 0.239 0.018 B:Q007T0:0.017
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 55.0 0.239 T -107.9 160.2 51.0 0.222 0.017 B:Q007T0:0.017
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 53.0 0.23 S -121.9 161.2 50.0 0.217 0.013 B:Q007T0:0.013
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:169 A:169 62.0 0.27 T -132.7 170.6 56.0 0.243 0.027 B:Q007T0:0.026
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 TYR A:169 A:169 62.0 0.27 S -119.7 160.7 61.0 0.265 0.005 B:Q007T0:0.004
 HOH
 2.585
 OH
 O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 TYR A:169 A:169 58.0 0.252 S -118.9 164.4 57.0 0.248 0.004 B:Q007T0:0.004
 HOH
 6.403
 N
 O
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 TYR A:168 A:168 51.0 0.222 S -113.3 173.3 46.0 0.2 0.022 C:None:0.022
 UNL
UNL
HOH
 3.748
6.855
2.765
 C
O
O
 O1
O1
O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 TYR A:168 A:168 53.0 0.23 S -127.3 159.1 49.0 0.213 0.017 C:None:0.017
 HOH
 3.343
 CB
 O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 TYR A:168 A:168 55.0 0.239 S -113.4 165.7 52.0 0.226 0.013 B:Q9YHT2:0.004
C:A0A3Q2U2Y6:0.009
 UNL
UNL
UNL
UNL
UNL
HOH
 3.650
6.877
6.979
4.492
9.835
3.220
 O
OH
O
CE1
O
CA
 O
O
O
N3
O
O
TYR E:168 N:168 55.0 0.239 S -111.9 164.2 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 TYR A:168 A:168 59.0 0.257 S -120.8 172.4 50.0 0.217 0.04 B:Q9YHT2:0.013
C:None:0.03
 UNL
HOH
 8.800
3.093
 N
O
 O1
O
TYR E:168 N:168 58.0 0.252 S -119.4 173.4 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 TYR A:168 A:168 53.0 0.23 S -120.6 166.0 49.0 0.213 0.017 C:None:0.017
 UNL
UNL
HOH
 4.402
9.970
3.204
 C
O
CB
 O1
O1
O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 TYR A:168 A:168 56.0 0.243 S -113.8 168.1 51.0 0.222 0.021 B:Q9YHT2:0.013
C:None:0.013
 UNL
HOH
 8.794
2.974
 N
O
 C2
O
TYR E:168 N:168 57.0 0.248 S -113.7 168.1 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:168 A:168 52.0 0.226 S -120.0 162.3 48.0 0.209 0.017 B:Q9YHT2:0.017
 UNL
UNL
UNL
HOH
 7.214
7.720
8.099
3.163
 O
OH
OH
CA
 N2
O
O
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:168 A:168 52.0 0.226 S -122.4 162.1 48.0 0.209 0.017 B:Q9YHT2:0.009
C:D0VWW3:0.004
 UNL
UNL
HOH
 6.948
8.317
2.807
 OH
O
O
 N1
C2
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:168 A:168 51.0 0.222 S -122.4 163.1 44.0 0.191 0.031 B:Q9YHT2:0.017
C:D0VWW3:0.017
 UNL
UNL
UNL
HOH
 8.278
9.615
7.708
2.836
 OH
OH
O
O
 O
O
C2
O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 TYR A:168 A:168 54.0 0.235 S -113.9 170.3 49.0 0.213 0.022 B:Q9YHT2:0.013
C:D0VWW3:0.009
 UNL
UNL
UNL
HOH
 4.269
9.990
8.703
3.560
 O
OH
OH
CA
 O8
O
N3
O
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:168 A:168 57.0 0.248 S -107.4 171.5 52.0 0.226 0.022 B:Q9YHT2:0.013
C:D0VWW3:0.013
 UNL
UNL
HOH
 4.379
8.844
6.430
 O
OH
C
 O8
O
O
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:168 A:168 54.0 0.235 S -121.4 162.2 51.0 0.222 0.013 B:Q9YHT2:0.013
 UNL
UNL
HOH
 9.818
7.843
3.119
 N
O
OH
 O1
C2
O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:168 A:168 52.0 0.226 S -119.0 165.6 46.0 0.2 0.026 B:Q9YHT2:0.017
C:D0VWW3:0.009
 UNL
UNL
UNL
HOH
 8.293
9.595
7.791
2.931
 OH
OH
O
O
 O
O
C2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 TYR A:211 A:211 31.0 0.135 S -103.2 -179.0