Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 228417 | . | A | C | CCDS3853.1:NM_004168.2:c.739Ata>Cta_NP_004159.2:p.247I>L | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | ILE | A:215 | A:247 | 0.0 | 0.0 | E | -93.3 | 94.8 | 0.0 | 0.0 | 0.0 |
FAD HOH |
9.203 7.320 |
CD1 CG2 |
C2A O |
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ILE | C:215 | C:247 | 0.0 | 0.0 | E | -84.2 | 99.5 | NA | NA | NA | |||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ILE | A:247 | A:205 | 0.0 | 0.0 | E | -86.3 | 111.9 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.947 9.858 |
CD1 CG2 |
C2A O |
||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ILE | A:247 | A:205 | 0.0 | 0.0 | E | -100.3 | 106.9 | 0.0 | 0.0 | 0.0 |
FAD |
8.904 |
CD1 |
C2A |
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1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -92.4 | 107.3 | 0.0 | 0.0 | 0.0 |
FAD HOH |
9.091 6.734 |
CD1 O |
C2A O |
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1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -87.4 | 106.0 | 0.0 | 0.0 | 0.0 |
FAD |
9.591 |
CD1 |
C2A |
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3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -96.1 | 113.3 | 0.0 | 0.0 | 0.0 |
FAD |
9.158 |
CD1 |
C2A |
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3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -97.9 | 115.6 | 0.0 | 0.0 | 0.0 |
FAD |
9.021 |
CD1 |
C2A |
||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -98.2 | 106.3 | 0.0 | 0.0 | 0.0 |
FAD |
9.061 |
CD1 |
C2A |
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3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -94.1 | 99.3 | 0.0 | 0.0 | 0.0 |
FAD |
8.748 |
CD1 |
C2A |
||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -116.0 | 98.8 | 0.0 | 0.0 | 0.0 |
FAD |
8.679 |
CD1 |
C2A |
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3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -107.7 | 104.3 | 0.0 | 0.0 | 0.0 |
FAD |
8.992 |
CD1 |
C2A |
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3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -102.1 | 107.7 | 0.0 | 0.0 | 0.0 |
FAD |
8.990 |
CD1 |
C2A |
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3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -84.8 | 100.3 | 0.0 | 0.0 | 0.0 |
FAD |
8.615 |
CD1 |
C2A |
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3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -105.2 | 101.3 | 0.0 | 0.0 | 0.0 |
FAD |
9.193 |
CD1 |
C2A |
||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -106.9 | 92.3 | 0.0 | 0.0 | 0.0 |
FAD |
9.660 |
CD1 |
N7A |
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3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -85.1 | 107.8 | 0.0 | 0.0 | 0.0 |
FAD |
8.856 |
CD1 |
C2A |
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3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -106.3 | 102.9 | 0.0 | 0.0 | 0.0 |
FAD |
9.157 |
CD1 |
C2A |
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3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -85.4 | 108.3 | 0.0 | 0.0 | 0.0 |
FAD |
8.699 |
CD1 |
C2A |
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3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -86.5 | 110.3 | 0.0 | 0.0 | 0.0 |
FAD |
8.690 |
CD1 |
C2A |
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3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -89.6 | 118.9 | 0.0 | 0.0 | 0.0 |
FAD |
9.172 |
CD1 |
C2A |
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3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -94.8 | 123.1 | 0.0 | 0.0 | 0.0 |
FAD |
8.940 |
CD1 |
C2A |
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3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -98.6 | 88.7 | 0.0 | 0.0 | 0.0 |
FAD |
8.948 |
CD1 |
C2A |
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3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -94.7 | 113.0 | 0.0 | 0.0 | 0.0 |
FAD HOH |
9.076 8.922 |
CD1 CG1 |
C2A O |
||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ILE | A:205 | A:205 | 0.0 | 0.0 | E | -93.2 | 113.0 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.873 7.900 |
CD1 CG2 |
C2A O |
||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -107.2 | 109.6 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.834 5.849 |
CE1 CE2 |
C2A O |
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1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -103.8 | 100.6 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.932 6.206 |
CE1 O |
C2A O |
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2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -103.1 | 106.6 | 0.0 | 0.0 | 0.0 |
FAD UNL UNL UNL UNL HOH |
8.812 9.981 9.142 7.608 8.702 6.227 |
CE1 CZ N CZ CZ CE2 |
C2A O O O O O |
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PHE | E:204 | N:204 | 1.0 | 0.005 | E | -103.5 | 106.1 | NA | NA | NA | |||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -101.0 | 109.8 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.969 5.660 |
CE1 CZ |
C2A O |
||
PHE | E:204 | N:204 | 1.0 | 0.005 | E | -102.6 | 106.1 | NA | NA | NA | |||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -107.2 | 98.8 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.757 5.545 |
CE1 O |
C2A O |
||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -104.1 | 109.0 | 0.0 | 0.0 | 0.0 |
AZI FAD UNL HOH |
8.083 8.816 8.626 6.077 |
CZ CE1 CE2 CE2 |
N1 C2A C2 O |
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PHE | E:204 | N:204 | 0.0 | 0.0 | E | -104.1 | 107.6 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -108.2 | 95.4 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.694 6.196 |
CE2 O |
C2A O |
||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -102.2 | 111.3 | 0.0 | 0.0 | 0.0 |
FAD UNL UNL UNL UNL HOH |
8.642 9.951 9.657 8.441 9.342 6.400 |
CE2 C CZ CZ CZ O |
C2A C1 O O O O |
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6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -108.0 | 102.0 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.798 6.215 |
CE1 O |
C2A O |
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6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -99.1 | 114.9 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.823 9.186 |
CE1 CD2 |
C2A O |
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6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -100.2 | 119.0 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.742 8.706 |
CE1 CD2 |
C2A O |
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6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -104.5 | 102.7 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.616 6.211 |
CE1 O |
C2A O |
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6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | PHE | A:204 | A:204 | 0.0 | 0.0 | E | -104.2 | 99.9 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.756 6.349 |
CE1 O |
C2A O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | ILE | A:247 | A:247 | 0.0 | 0.0 | E | -108.6 | 98.4 |