Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 230997 . C A CCDS3853.1:NM_004168.2:c.777taC>taA_NP_004159.2:p.259Y>* Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6vax 1 P31040 100.0 0.0 X-RAY
 2020-08-26 TYR A:227 A:259 2.0 0.009 -138.7 40.0 2.0 0.009 0.0 FAD
K
HOH
 8.292
6.715
3.135
 N
CE1
OH
 O1A
K
O
TYR C:227 C:259 2.0 0.009 -139.5 38.8 NA NA NA
4ytp 1 Q0QF01 94.58 0.0 X-RAY
 2015-08-05 TYR A:259 A:217 2.0 0.009 -135.3 30.1 2.0 0.009 0.0 FAD
 8.013
 N
 O2A
4yxd 1 Q0QF01 94.58 0.0 X-RAY
 2016-03-02 TYR A:259 A:217 1.0 0.004 -146.5 37.7 1.0 0.004 0.0 FAD
 7.825
 N
 O2A
1zoy 1 Q0QF01 96.3 0.0 X-RAY
 2005-07-12 TYR A:217 A:217 2.0 0.009 -142.2 44.0 2.0 0.009 0.0 FAD
HOH
 7.968
2.917
 N
OH
 O2A
O
1zp0 1 ? 96.3 0.0 X-RAY
 2005-07-12 TYR A:217 A:217 1.0 0.004 -140.0 43.3 1.0 0.004 0.0 FAD
 7.872
 N
 O2A
3abv 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -130.3 39.4 2.0 0.009 0.0 FAD
 7.490
 N
 O2A
3ae1 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -136.6 38.1 2.0 0.009 0.0 FAD
 7.902
 N
 O2A
3ae2 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -123.6 38.6 2.0 0.009 0.0 FAD
 7.587
 N
 O1A
3ae3 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 3.0 0.013 -140.7 45.7 3.0 0.013 0.0 FAD
 7.886
 N
 O2A
3ae4 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -131.1 42.9 2.0 0.009 0.0 FAD
 7.932
 N
 O2A
3ae5 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -124.7 40.8 2.0 0.009 0.0 FAD
 7.620
 N
 O2A
3ae6 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 3.0 0.013 -129.5 38.7 3.0 0.013 0.0 FAD
 7.579
 N
 O2A
3ae7 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 1.0 0.004 -114.0 49.8 1.0 0.004 0.0 FAD
 7.903
 N
 O2A
3ae8 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 1.0 0.004 -129.4 48.1 1.0 0.004 0.0 FAD
 8.124
 N
 O2A
3ae9 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -120.2 45.4 2.0 0.009 0.0 FAD
 8.121
 N
 O1A
3aea 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -121.0 50.5 2.0 0.009 0.0 FAD
 8.327
 N
 O1A
3aeb 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -125.3 37.7 2.0 0.009 0.0 FAD
 7.431
 N
 O2A
3aec 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 1.0 0.004 -118.2 47.4 1.0 0.004 0.0 FAD
 8.049
 N
 O3'
3aed 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -138.6 50.1 2.0 0.009 0.0 FAD
 7.885
 N
 O1A
3aee 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 1.0 0.004 -144.1 46.3 1.0 0.004 0.0 FAD
 7.952
 N
 O2A
3aef 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -134.2 37.9 2.0 0.009 0.0 FAD
 7.997
 N
 O2A
3aeg 1 Q0QF01 96.3 0.0 X-RAY
 2011-02-09 TYR A:217 A:217 2.0 0.009 -116.0 33.5 2.0 0.009 0.0 FAD
 7.675
 N
 O2A
3sfd 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 TYR A:217 A:217 2.0 0.009 -125.9 25.4 2.0 0.009 0.0 FAD
HOH
 7.639
2.851
 N
OH
 O2A
O
3sfe 1 Q0QF01 96.3 0.0 X-RAY
 2011-09-07 TYR A:217 A:217 2.0 0.009 -129.8 36.4 2.0 0.009 0.0 FAD
 7.587
 N
 O2A
1yq3 1 Q9YHT1 91.79 0.0 X-RAY
 2005-12-20 TYR A:216 A:216 2.0 0.009 -139.8 52.5 2.0 0.009 0.0 FAD
HOH
 7.890
2.954
 N
OH
 O1A
O
1yq4 1 50736125 91.79 0.0 X-RAY
 2005-12-20 TYR A:216 A:216 2.0 0.009 -141.0 55.7 2.0 0.009 0.0 FAD
HOH
 7.598
3.088
 N
OH
 O1A
O
2fbw 1 F1NPJ4 91.79 0.0 X-RAY
 2005-12-20 TYR A:216 A:216 2.0 0.009 -139.3 38.5 2.0 0.009 0.0 FAD
K
UNL
HOH
 7.814
7.265
9.956
2.961
 N
CE1
O
OH
 O1A
K
O
O
TYR E:216 N:216 2.0 0.009 -139.7 41.2 NA NA NA
2h88 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 TYR A:216 A:216 3.0 0.013 -136.6 39.6 3.0 0.013 0.0 K
FAD
HOH
 7.132
7.858
2.850
 CE2
N
OH
 K
O1A
O
TYR E:216 N:216 1.0 0.004 -137.3 39.3 NA NA NA
2h89 1 Q9YHT1 91.79 0.0 X-RAY
 2006-06-20 TYR A:216 A:216 2.0 0.009 -150.7 52.0 2.0 0.009 0.0 K
FAD
HOH
 7.509
7.919
3.034
 CE2
N
N
 K
O1A
O
2wqy 1 Q9YHT1 91.79 0.0 X-RAY
 2010-08-25 TYR A:216 A:216 2.0 0.009 -136.7 42.7 2.0 0.009 0.0 K
FAD
HOH
 7.223
7.852
3.002
 CE2
N
OH
 K
O1A
O
TYR E:216 N:216 2.0 0.009 -137.2 42.4 NA NA NA
6myo 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:216 A:216 2.0 0.009 -144.8 43.9 2.0 0.009 0.0 FAD
K
PEG
HOH
 7.721
7.289
9.872
3.104
 N
CE1
O
OH
 O1A
K
C2
O
6myp 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:216 A:216 4.0 0.017 -135.7 50.0 4.0 0.017 0.0 FAD
K
UNL
HOH
 8.050
7.232
6.787
3.156
 N
CE1
OH
OH
 O1A
K
C1
O
6myq 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:216 A:216 2.0 0.009 -136.3 45.0 2.0 0.009 0.0 FAD
K
PEG
HOH
 7.741
7.321
9.802
3.049
 N
CE1
O
OH
 O1A
K
C2
O
6myr 1 F1NPJ4 91.79 0.0 X-RAY
 2019-10-16 TYR A:216 A:216 2.0 0.009 -142.8 37.3 2.0 0.009 0.0 FAD
K
PEG
UNL
UNL
HOH
 7.659
7.071
9.845
8.981
5.522
4.850
 N
CE1
O
N
N
N
 O1A
K
C2
O
O
O
6mys 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:216 A:216 2.0 0.009 -137.6 41.4 2.0 0.009 0.0 FAD
K
HOH
 7.721
7.235
5.293
 N
CE1
N
 O1A
K
O
6myt 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:216 A:216 2.0 0.009 -134.9 44.0 2.0 0.009 0.0 FAD
K
UNL
HOH
 8.139
7.162
6.509
3.368
 N
CE2
N
N
 O1A
K
O
O
6myu 1 F1NPJ4 91.79 0.0 X-RAY
 2019-11-06 TYR A:216 A:216 2.0 0.009 -145.6 45.1 2.0 0.009 0.0 FAD
K
PEG
HOH
 7.767
7.266
9.804
2.769
 N
CE1
O
OH
 O1A
K
C2
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p31040-f1 1 P31040 100.0 0.0 TYR A:259 A:259 1.0 0.004 -131.1 32.2