Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 230998 | . | G | A | CCDS3853.1:NM_004168.2:c.778Ggg>Agg_NP_004159.2:p.260G>R | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | GLY | A:228 | A:260 | 0.0 | 0.0 | G | -61.0 | -19.6 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.472 7.190 |
CA N |
C8M O |
||
| GLY | C:228 | C:260 | 1.0 | 0.013 | G | -62.9 | -19.0 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | GLY | A:260 | A:218 | 0.0 | 0.0 | G | -47.5 | -20.7 | 0.0 | 0.0 | 0.0 |
FAD |
8.226 |
CA |
C8M |
||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | GLY | A:260 | A:218 | 1.0 | 0.013 | G | -57.7 | -19.8 | 1.0 | 0.013 | 0.0 |
FAD |
8.595 |
CA |
C8M |
||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLY | A:218 | A:218 | 1.0 | 0.013 | G | -58.1 | -28.8 | 1.0 | 0.013 | 0.0 |
FAD HOH |
8.335 3.926 |
CA N |
C8M O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLY | A:218 | A:218 | 0.0 | 0.0 | G | -54.9 | -35.2 | 0.0 | 0.0 | 0.0 |
FAD |
7.860 |
CA |
C8M |
||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 2.0 | 0.027 | G | -52.7 | -29.2 | 2.0 | 0.027 | 0.0 |
FAD |
8.129 |
CA |
C8M |
||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 0.0 | 0.0 | G | -55.0 | -11.2 | 0.0 | 0.0 | 0.0 |
FAD |
7.632 |
CA |
C8M |
||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 1.0 | 0.013 | G | -48.4 | -26.5 | 1.0 | 0.013 | 0.0 |
FAD |
7.895 |
CA |
C8M |
||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 2.0 | 0.027 | G | -60.1 | -21.8 | 2.0 | 0.027 | 0.0 |
FAD |
8.123 |
CA |
C8M |
||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 1.0 | 0.013 | G | -48.7 | -30.6 | 1.0 | 0.013 | 0.0 |
FAD |
8.001 |
CA |
C8M |
||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 1.0 | 0.013 | G | -55.9 | -22.3 | 1.0 | 0.013 | 0.0 |
FAD |
7.666 |
CA |
C8M |
||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 0.0 | 0.0 | G | -56.2 | -27.2 | 0.0 | 0.0 | 0.0 |
FAD |
7.523 |
CA |
C8M |
||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 1.0 | 0.013 | G | -61.6 | -25.4 | 1.0 | 0.013 | 0.0 |
FAD |
7.618 |
CA |
C8M |
||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 1.0 | 0.013 | G | -60.5 | -23.3 | 1.0 | 0.013 | 0.0 |
FAD |
7.766 |
CA |
C8M |
||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 3.0 | 0.04 | G | -58.5 | -23.0 | 3.0 | 0.04 | 0.0 |
FAD |
8.072 |
CA |
C8M |
||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 2.0 | 0.027 | G | -62.6 | -26.3 | 2.0 | 0.027 | 0.0 |
FAD |
7.720 |
CA |
C8M |
||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 1.0 | 0.013 | G | -51.3 | -23.2 | 1.0 | 0.013 | 0.0 |
FAD |
7.946 |
CA |
C8M |
||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 1.0 | 0.013 | G | -58.1 | -28.2 | 1.0 | 0.013 | 0.0 |
FAD |
7.370 |
CA |
C8M |
||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 2.0 | 0.027 | G | -54.3 | -34.3 | 2.0 | 0.027 | 0.0 |
FAD |
8.040 |
CA |
C8M |
||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 0.0 | 0.0 | G | -60.4 | -31.8 | 0.0 | 0.0 | 0.0 |
FAD |
7.744 |
CA |
C8M |
||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 0.0 | 0.0 | G | -58.5 | -14.3 | 0.0 | 0.0 | 0.0 |
FAD |
8.594 |
CA |
C8M |
||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLY | A:218 | A:218 | 1.0 | 0.013 | G | -57.4 | -10.8 | 1.0 | 0.013 | 0.0 |
FAD |
7.797 |
CA |
C8M |
||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLY | A:218 | A:218 | 0.0 | 0.0 | G | -44.0 | -27.3 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.396 7.595 |
CA N |
C8M O |
||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLY | A:218 | A:218 | 2.0 | 0.027 | G | -51.8 | -29.4 | 2.0 | 0.027 | 0.0 |
FAD |
8.260 |
CA |
C8M |
||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLY | A:217 | A:217 | 0.0 | 0.0 | G | -62.5 | -20.9 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.010 3.048 |
CA N |
C8M O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLY | A:217 | A:217 | 1.0 | 0.013 | G | -66.4 | -19.9 | 1.0 | 0.013 | 0.0 |
FAD HOH |
8.029 5.044 |
CA N |
C8M O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLY | A:217 | A:217 | 0.0 | 0.0 | G | -60.2 | -22.4 | 0.0 | 0.0 | 0.0 |
FAD UNL UNL HOH |
8.288 9.627 8.939 2.886 |
CA C O N |
C8M O N3 O |
||
| GLY | E:217 | N:217 | 1.0 | 0.013 | G | -63.2 | -24.9 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLY | A:217 | A:217 | 1.0 | 0.013 | G | -59.6 | -22.6 | 1.0 | 0.013 | 0.0 |
AZI FAD HOH |
8.635 8.201 2.947 |
O CA N |
N3 C8M O |
||
| GLY | E:217 | N:217 | 1.0 | 0.013 | G | -59.1 | -21.3 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLY | A:217 | A:217 | 1.0 | 0.013 | G | -61.4 | -18.7 | 1.0 | 0.013 | 0.0 |
FAD HOH |
8.274 3.377 |
CA N |
C8M O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | GLY | A:217 | A:217 | 0.0 | 0.0 | G | -60.2 | -22.7 | 0.0 | 0.0 | 0.0 |
FAD HOH |
8.024 2.820 |
CA N |
C8M O |
||
| GLY | E:217 | N:217 | 0.0 | 0.0 | G | -59.7 | -23.6 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:217 | A:217 | 1.0 | 0.013 | G | -58.8 | -21.6 | 1.0 | 0.013 | 0.0 |
FAD PEG UNL UNL HOH |
8.121 7.918 8.966 9.805 3.246 |
CA O O O N |
C8M C2 O2 O O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:217 | A:217 | 0.0 | 0.0 | G | -64.1 | -18.6 | 0.0 | 0.0 | 0.0 |
FAD PEG UNL HOH |
8.087 8.107 7.651 3.189 |
CA O O N |
C8M C2 O03 O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:217 | A:217 | 2.0 | 0.027 | G | -55.9 | -29.3 | 2.0 | 0.027 | 0.0 |
FAD PEG UNL HOH |
8.166 7.837 9.029 2.907 |
CA O O N |
C8M C2 O2 O |
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| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | GLY | A:217 | A:217 | 0.0 | 0.0 | G | -54.4 | -23.2 | 0.0 | 0.0 | 0.0 |
FAD PEG UNL UNL HOH |
8.160 7.875 4.988 7.944 6.507 |
CA O N O N |
C8M C2 O O2 O |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:217 | A:217 | 0.0 | 0.0 | G | -61.9 | -14.7 | 0.0 | 0.0 | 0.0 |
FAD UNL HOH |
8.128 8.912 6.935 |
CA O N |
C8M N3 O |
||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:217 | A:217 | 0.0 | 0.0 | G | -60.9 | -20.3 | 0.0 | 0.0 | 0.0 |
FAD PEG UNL UNL UNL HOH |
8.275 8.199 9.259 9.177 7.194 2.920 |
CA O O O N N |
C8M C2 O2 C1 O O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLY | A:217 | A:217 | 1.0 | 0.013 | G | -54.0 | -25.9 | 1.0 | 0.013 | 0.0 |
FAD PEG UNL HOH |
8.118 7.891 9.094 2.782 |
CA O O N |
C8M C2 O2 O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | GLY | A:260 | A:260 | 0.0 | 0.0 | G | -54.9 | -22.8 | |