Variant
Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 231062 | . | C | A | CCDS3853.1:NM_004168.2:c.842aCc>aAc_NP_004159.2:p.281T>N | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | THR | A:249 | A:281 | 3.0 | 0.021 | H | -67.9 | -45.0 | 3.0 | 0.021 | 0.0 |
EDO HOH |
8.750 5.068 |
O O |
C2 O |
||
THR | C:249 | C:281 | 4.0 | 0.029 | H | -69.9 | -45.7 | NA | NA | NA | |||||||||||||
4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | THR | A:281 | A:239 | 3.0 | 0.021 | H | -54.9 | -49.5 | 3.0 | 0.021 | 0.0 |
HOH |
3.061 |
O |
O |
||
4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | THR | A:281 | A:239 | 5.0 | 0.036 | H | -60.1 | -39.5 | 5.0 | 0.036 | 0.0 | ||||||
1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | THR | A:239 | A:239 | 2.0 | 0.014 | H | -62.2 | -43.0 | 2.0 | 0.014 | 0.0 |
HOH |
2.867 |
OG1 |
O |
||
1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | THR | A:239 | A:239 | 3.0 | 0.021 | H | -61.5 | -46.9 | 3.0 | 0.021 | 0.0 | ||||||
3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 2.0 | 0.014 | H | -62.8 | -48.5 | 2.0 | 0.014 | 0.0 | ||||||
3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 3.0 | 0.021 | H | -62.7 | -49.0 | 3.0 | 0.021 | 0.0 | ||||||
3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 2.0 | 0.014 | H | -62.3 | -46.5 | 2.0 | 0.014 | 0.0 | ||||||
3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 2.0 | 0.014 | H | -70.0 | -27.7 | 2.0 | 0.014 | 0.0 | ||||||
3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 3.0 | 0.021 | H | -63.3 | -43.5 | 3.0 | 0.021 | 0.0 | ||||||
3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 1.0 | 0.007 | H | -74.1 | -28.5 | 1.0 | 0.007 | 0.0 | ||||||
3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 2.0 | 0.014 | H | -61.8 | -40.5 | 2.0 | 0.014 | 0.0 | ||||||
3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 5.0 | 0.036 | H | -62.1 | -45.1 | 5.0 | 0.036 | 0.0 | ||||||
3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 6.0 | 0.043 | H | -61.4 | -52.4 | 6.0 | 0.043 | 0.0 | ||||||
3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 5.0 | 0.036 | H | -60.4 | -45.1 | 5.0 | 0.036 | 0.0 | ||||||
3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 2.0 | 0.014 | H | -72.8 | -23.4 | 2.0 | 0.014 | 0.0 | ||||||
3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 3.0 | 0.021 | H | -58.0 | -52.2 | 3.0 | 0.021 | 0.0 | ||||||
3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 4.0 | 0.029 | H | -57.0 | -47.9 | 4.0 | 0.029 | 0.0 | ||||||
3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 6.0 | 0.043 | H | -56.3 | -55.5 | 6.0 | 0.043 | 0.0 | ||||||
3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 3.0 | 0.021 | H | -71.3 | -7.7 | 3.0 | 0.021 | 0.0 | ||||||
3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 2.0 | 0.014 | H | -61.3 | -54.2 | 2.0 | 0.014 | 0.0 | ||||||
3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | THR | A:239 | A:239 | 2.0 | 0.014 | H | -68.5 | -34.6 | 2.0 | 0.014 | 0.0 | ||||||
3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | THR | A:239 | A:239 | 4.0 | 0.029 | H | -65.9 | -38.2 | 4.0 | 0.029 | 0.0 |
HOH |
6.338 |
N |
O |
||
3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | THR | A:239 | A:239 | 2.0 | 0.014 | H | -58.4 | -47.0 | 2.0 | 0.014 | 0.0 | ||||||
1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | THR | A:238 | A:238 | 1.0 | 0.007 | H | -52.8 | -47.4 | 1.0 | 0.007 | 0.0 |
HOH |
2.698 |
O |
O |
||
1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | THR | A:238 | A:238 | 3.0 | 0.021 | H | -43.0 | -51.0 | 3.0 | 0.021 | 0.0 |
HOH |
3.235 |
O |
O |
||
2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | THR | A:238 | A:238 | 2.0 | 0.014 | H | -56.8 | -44.6 | 2.0 | 0.014 | 0.0 |
UNL UNL UNL HOH |
9.553 9.789 7.418 2.727 |
N C C OG1 |
N3 O O O |
||
THR | E:238 | N:238 | 3.0 | 0.021 | H | -58.9 | -44.3 | NA | NA | NA | |||||||||||||
2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | THR | A:238 | A:238 | 3.0 | 0.021 | H | -56.7 | -45.9 | 3.0 | 0.021 | 0.0 |
HOH |
2.909 |
O |
O |
||
THR | E:238 | N:238 | 3.0 | 0.021 | H | -57.0 | -46.3 | NA | NA | NA | |||||||||||||
2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | THR | A:238 | A:238 | 4.0 | 0.029 | H | -49.1 | -51.8 | 4.0 | 0.029 | 0.0 |
UNL HOH |
4.741 2.963 |
O OG1 |
O1 O |
||
2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | THR | A:238 | A:238 | 2.0 | 0.014 | H | -59.0 | -41.7 | 2.0 | 0.014 | 0.0 |
HOH |
2.705 |
OG1 |
O |
||
THR | E:238 | N:238 | 2.0 | 0.014 | H | -58.6 | -42.1 | NA | NA | NA | |||||||||||||
6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:238 | A:238 | 2.0 | 0.014 | H | -55.6 | -43.8 | 2.0 | 0.014 | 0.0 |
HOH |
2.447 |
O |
O |
||
6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:238 | A:238 | 3.0 | 0.021 | H | -64.8 | -41.8 | 3.0 | 0.021 | 0.0 |
UNL HOH |
8.832 2.763 |
OG1 O |
C2 O |
||
6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:238 | A:238 | 2.0 | 0.014 | H | -62.1 | -41.6 | 2.0 | 0.014 | 0.0 |
UNL HOH |
9.010 2.718 |
O O |
O1 O |
||
6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | THR | A:238 | A:238 | 2.0 | 0.014 | H | -59.4 | -42.4 | 2.0 | 0.014 | 0.0 |
HOH |
2.668 |
O |
O |
||
6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:238 | A:238 | 2.0 | 0.014 | H | -66.1 | -44.3 | 2.0 | 0.014 | 0.0 |
HOH |
7.278 |
CG2 |
O |
||
6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:238 | A:238 | 2.0 | 0.014 | H | -62.7 | -44.9 | 2.0 | 0.014 | 0.0 |
UNL HOH |
9.441 2.813 |
O OG1 |
O1 O |
||
6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | THR | A:238 | A:238 | 1.0 | 0.007 | H | -58.0 | -46.7 | 1.0 | 0.007 | 0.0 |
UNL HOH |
8.958 2.715 |
O OG1 |
O1 O |
AlphaFold DB
Entity | Residue | Monomer | View | ||||||||||
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ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | THR | A:281 | A:281 | 2.0 | 0.014 | H | -62.5 | -45.0 |