Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 231100 | . | C | A | CCDS3853.1:NM_004168.2:c.880Cag>Aag_NP_004159.2:p.294Q>K | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | GLN | A:262 | A:294 | 13.0 | 0.072 | E | -84.2 | 131.8 | 13.0 | 0.072 | 0.0 |
FAD OAA GOL K HOH |
7.545 6.382 3.808 9.329 5.351 |
OE1 OE1 CA N N |
C1' O4 O3 K O |
||
| GLN | C:262 | C:294 | 10.0 | 0.056 | E | -86.3 | 133.1 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | GLN | A:294 | A:252 | 0.0 | 0.0 | E | -87.9 | 120.9 | 0.0 | 0.0 | 0.0 |
FAD |
7.259 |
OE1 |
C1' |
||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | GLN | A:294 | A:252 | 0.0 | 0.0 | E | -84.3 | 120.7 | 0.0 | 0.0 | 0.0 |
FAD |
7.148 |
OE1 |
C1' |
||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -83.9 | 124.8 | 0.0 | 0.0 | 0.0 |
FAD HOH |
6.887 5.784 |
OE1 N |
C1' O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -83.7 | 125.1 | 0.0 | 0.0 | 0.0 |
FAD 3NP |
7.049 2.825 |
OE1 NE2 |
C1' O1 |
||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 1.0 | 0.006 | E | -71.6 | 121.5 | 1.0 | 0.006 | 0.0 |
FAD MLI |
6.679 5.638 |
OE1 OE1 |
C1' O9 |
||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -64.4 | 116.8 | 0.0 | 0.0 | 0.0 |
FAD MLI |
7.674 6.108 |
OE1 OE1 |
C1' O6 |
||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 1.0 | 0.006 | E | -76.9 | 122.6 | 1.0 | 0.006 | 0.0 |
FAD MLI |
7.069 5.541 |
OE1 OE1 |
C1' O9 |
||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -84.9 | 125.9 | 0.0 | 0.0 | 0.0 |
FAD |
7.425 |
OE1 |
C1' |
||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 1.0 | 0.006 | E | -84.5 | 131.5 | 1.0 | 0.006 | 0.0 |
FAD MLI |
7.522 5.792 |
OE1 OE1 |
C1' O9 |
||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -77.6 | 128.1 | 0.0 | 0.0 | 0.0 |
FAD MLI |
7.286 5.563 |
OE1 OE1 |
C1' O8 |
||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -77.0 | 127.5 | 0.0 | 0.0 | 0.0 |
FAD |
7.120 |
OE1 |
C1' |
||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -81.1 | 139.0 | 0.0 | 0.0 | 0.0 |
FAD |
7.129 |
OE1 |
C1' |
||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -78.6 | 132.5 | 0.0 | 0.0 | 0.0 |
FAD |
7.471 |
OE1 |
C1' |
||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -81.3 | 122.7 | 0.0 | 0.0 | 0.0 |
FAD MLI |
7.274 5.990 |
OE1 OE1 |
C1' O8 |
||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 1.0 | 0.006 | E | -83.5 | 128.8 | 1.0 | 0.006 | 0.0 |
FAD MLI |
7.439 6.222 |
OE1 OE1 |
C1' O6 |
||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -79.9 | 126.6 | 0.0 | 0.0 | 0.0 |
FAD MLI |
6.838 5.013 |
OE1 OE1 |
C1' O9 |
||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -69.5 | 116.9 | 0.0 | 0.0 | 0.0 |
FAD |
8.368 |
CG |
C1' |
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| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -78.4 | 128.2 | 0.0 | 0.0 | 0.0 |
FAD MLI |
6.975 5.313 |
OE1 OE1 |
C1' O8 |
||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -77.3 | 122.7 | 0.0 | 0.0 | 0.0 |
FAD |
7.170 |
OE1 |
C1' |
||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -74.2 | 132.7 | 0.0 | 0.0 | 0.0 |
FAD HOH |
7.074 5.685 |
OE1 OE1 |
C1' O |
||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -80.2 | 124.8 | 0.0 | 0.0 | 0.0 |
FAD |
7.098 |
OE1 |
C1' |
||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLN | A:252 | A:252 | 0.0 | 0.0 | E | -82.6 | 124.5 | 0.0 | 0.0 | 0.0 |
FAD OAA HOH |
6.877 4.886 5.110 |
OE1 OE1 N |
C1' O2 O |
||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | GLN | A:252 | A:252 | 1.0 | 0.006 | E | -81.9 | 122.2 | 1.0 | 0.006 | 0.0 |
FAD OAA |
6.697 4.651 |
OE1 OE1 |
C1' O2 |
||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLN | A:251 | A:251 | 1.0 | 0.006 | E | -86.7 | 122.5 | 1.0 | 0.006 | 0.0 |
FAD TEO HOH |
6.838 4.502 3.057 |
OE1 OE1 NE2 |
C1' O4A O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLN | A:251 | A:251 | 1.0 | 0.006 | E | -91.8 | 126.4 | 1.0 | 0.006 | 0.0 |
FAD 3NP HOH |
6.652 4.323 2.802 |
OE1 OE1 NE2 |
C1' N1 O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | GLN | A:251 | A:251 | 1.0 | 0.006 | E | -83.2 | 122.9 | 1.0 | 0.006 | 0.0 |
FAD Y3P K HOH |
6.746 4.698 9.273 2.991 |
OE1 OE1 N NE2 |
C1' O4 K O |
||
| GLN | E:251 | N:251 | 2.0 | 0.011 | E | -85.7 | 119.1 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLN | A:251 | A:251 | 2.0 | 0.011 | E | -83.1 | 124.7 | 2.0 | 0.011 | 0.0 |
K FAD TEO HOH |
9.289 7.000 4.812 2.972 |
N OE1 OE1 NE2 |
K C1' O4B O |
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| GLN | E:251 | N:251 | 2.0 | 0.011 | E | -82.6 | 125.4 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | GLN | A:251 | A:251 | 0.0 | 0.0 | E | -89.7 | 126.2 | 0.0 | 0.0 | 0.0 |
K FAD MLI HOH |
9.164 7.174 4.955 3.093 |
N OE1 OE1 NE2 |
K C1' O8 O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | GLN | A:251 | A:251 | 1.0 | 0.006 | E | -83.7 | 124.7 | 1.0 | 0.006 | 0.0 |
K FAD OAA HOH |
9.185 6.870 4.739 2.893 |
N OE1 OE1 NE2 |
K C1' O1 O |
||
| GLN | E:251 | N:251 | 3.0 | 0.017 | E | -84.6 | 123.1 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:251 | A:251 | 1.0 | 0.006 | E | -88.6 | 122.7 | 1.0 | 0.006 | 0.0 |
FAD OAA K HOH |
7.108 4.541 9.161 2.815 |
OE1 OE1 CB NE2 |
C1' O1 K O |
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| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:251 | A:251 | 1.0 | 0.006 | E | -82.5 | 128.3 | 1.0 | 0.006 | 0.0 |
FAD OAA K UNL HOH |
7.134 4.543 9.317 9.819 3.289 |
OE1 OE1 N NE2 NE2 |
C1' O1 K N3 O |
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| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:251 | A:251 | 2.0 | 0.011 | E | -91.5 | 124.3 | 2.0 | 0.011 | 0.0 |
FAD Y3P K HOH |
6.859 4.549 9.227 2.887 |
OE1 OE1 N NE2 |
C1' O4 K O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | GLN | A:251 | A:251 | 1.0 | 0.006 | E | -86.9 | 131.4 | 1.0 | 0.006 | 0.0 |
FAD OAA K UNL UNL HOH |
7.198 4.633 9.340 9.899 9.241 7.110 |
OE1 OE1 N NE2 O NE2 |
C1' O1 K N3 O O |
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| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:251 | A:251 | 1.0 | 0.006 | E | -79.5 | 130.5 | 1.0 | 0.006 | 0.0 |
FAD K OAA HOH |
6.962 9.249 4.572 8.220 |
OE1 N OE1 N |
C1' K O1 O |
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| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:251 | A:251 | 2.0 | 0.011 | E | -84.9 | 127.6 | 2.0 | 0.011 | 0.0 |
FAD OAA K UNL UNL HOH |
6.914 4.521 9.247 9.674 8.856 3.218 |
OE1 OE1 N NE2 NE2 NE2 |
C1' O1 K N3 O O |
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| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | GLN | A:251 | A:251 | 1.0 | 0.006 | E | -94.1 | 120.4 | 1.0 | 0.006 | 0.0 |
FAD OAA K HOH |
6.969 4.607 9.216 3.086 |
OE1 OE1 N NE2 |
C1' O1 K O |
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AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | GLN | A:294 | A:294 | 1.0 | 0.006 | E | -83.8 | 123.8 | |