Variant
| Genome | Chromosome | Position | VCF ID | Ref | Alt | mRNA Change | mRNA Info | GRCh37 | chr5 | 233630 | . | C | A | CCDS3853.1:NM_004168.2:c.934Cgt>Agt_NP_004159.2:p.312R>S | Homo sapiens succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (SDHA), mRNA. |
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PDB
| Entity | Residue | Monomer | BioUnit | Ligand | View | ||||||||||||||||||
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| PDB | Entity | Uniprot | Identity | Evalue | ExpMethod | Date | Name | Label | Auth | ASA | rASA | SS | φ | ψ | ASA | rASA | ΔASA | Interaction | Name | Distance | Atom(p) | Atom(l) | |
| 6vax | 1 | P31040 | 100.0 | 0.0 |
X-RAY |
2020-08-26 | ARG | A:280 | A:312 | 6.0 | 0.027 | H | -68.5 | -21.8 | 6.0 | 0.027 | 0.0 |
OAA |
7.541 |
NH1 |
O2 |
||
| ARG | C:280 | C:312 | 7.0 | 0.031 | H | -67.0 | -21.7 | NA | NA | NA | |||||||||||||
| 4ytp | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2015-08-05 | ARG | A:312 | A:270 | 5.0 | 0.022 | H | -71.8 | -39.6 | 5.0 | 0.022 | 0.0 | ||||||
| 4yxd | 1 | Q0QF01 | 94.58 | 0.0 |
X-RAY |
2016-03-02 | ARG | A:312 | A:270 | 6.0 | 0.027 | H | -76.4 | -39.4 | 6.0 | 0.027 | 0.0 | ||||||
| 1zoy | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ARG | A:270 | A:270 | 5.0 | 0.022 | H | -66.0 | -42.9 | 5.0 | 0.022 | 0.0 |
HOH |
4.712 |
NH1 |
O |
||
| 1zp0 | 1 | ? | 96.3 | 0.0 |
X-RAY |
2005-07-12 | ARG | A:270 | A:270 | 4.0 | 0.018 | H | -65.0 | -42.9 | 4.0 | 0.018 | 0.0 |
3NP |
5.412 |
NH2 |
C2 |
||
| 3abv | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 7.0 | 0.031 | H | -70.6 | -38.9 | 7.0 | 0.031 | 0.0 |
MLI |
5.706 |
NH2 |
O6 |
||
| 3ae1 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 5.0 | 0.022 | H | -71.0 | -29.2 | 5.0 | 0.022 | 0.0 |
MLI |
5.983 |
NH2 |
O9 |
||
| 3ae2 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 9.0 | 0.04 | H | -67.3 | -35.3 | 9.0 | 0.04 | 0.0 |
MLI |
5.549 |
NH2 |
O7 |
||
| 3ae3 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 5.0 | 0.022 | G | -80.7 | -17.2 | 5.0 | 0.022 | 0.0 | ||||||
| 3ae4 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 6.0 | 0.027 | H | -65.5 | -40.6 | 6.0 | 0.027 | 0.0 |
MLI |
6.101 |
NH2 |
O6 |
||
| 3ae5 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 6.0 | 0.027 | H | -66.3 | -25.7 | 6.0 | 0.027 | 0.0 |
MLI |
6.517 |
NH2 |
C1 |
||
| 3ae6 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 4.0 | 0.018 | H | -75.0 | -24.6 | 4.0 | 0.018 | 0.0 | ||||||
| 3ae7 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 1.0 | 0.004 | H | -75.3 | 78.6 | 1.0 | 0.004 | 0.0 | ||||||
| 3ae8 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 5.0 | 0.022 | H | -71.2 | -30.2 | 5.0 | 0.022 | 0.0 | ||||||
| 3ae9 | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 4.0 | 0.018 | H | -74.7 | -28.7 | 4.0 | 0.018 | 0.0 |
MLI |
5.075 |
NH2 |
O9 |
||
| 3aea | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 4.0 | 0.018 | H | -74.6 | -28.9 | 4.0 | 0.018 | 0.0 |
MLI |
6.296 |
NH2 |
O8 |
||
| 3aeb | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 6.0 | 0.027 | H | -70.3 | -30.3 | 6.0 | 0.027 | 0.0 |
MLI |
5.560 |
NH2 |
O6 |
||
| 3aec | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 6.0 | 0.027 | H | -74.1 | -23.7 | 6.0 | 0.027 | 0.0 | ||||||
| 3aed | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 4.0 | 0.018 | H | -77.7 | -21.9 | 4.0 | 0.018 | 0.0 |
MLI |
6.092 |
NH2 |
O6 |
||
| 3aee | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 3.0 | 0.013 | T | -78.4 | -29.7 | 3.0 | 0.013 | 0.0 |
FAD |
9.714 |
NH2 |
O4 |
||
| 3aef | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 5.0 | 0.022 | H | -67.1 | -33.5 | 5.0 | 0.022 | 0.0 |
HOH |
6.956 |
NH2 |
O |
||
| 3aeg | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-02-09 | ARG | A:270 | A:270 | 4.0 | 0.018 | H | -77.9 | -29.2 | 4.0 | 0.018 | 0.0 |
FAD |
9.758 |
NH2 |
O4 |
||
| 3sfd | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ARG | A:270 | A:270 | 8.0 | 0.036 | H | -67.1 | -40.5 | 8.0 | 0.036 | 0.0 |
OAA HOH |
6.175 8.851 |
NH2 N |
O4 O |
||
| 3sfe | 1 | Q0QF01 | 96.3 | 0.0 |
X-RAY |
2011-09-07 | ARG | A:270 | A:270 | 7.0 | 0.031 | H | -70.8 | -39.2 | 7.0 | 0.031 | 0.0 |
OAA HOH |
6.222 7.406 |
NH2 O |
O4 O |
||
| 1yq3 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:269 | A:269 | 5.0 | 0.022 | H | -74.6 | -33.9 | 5.0 | 0.022 | 0.0 |
TEO HOH |
5.437 2.726 |
NH2 O |
O1B O |
||
| 1yq4 | 1 | 50736125 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:269 | A:269 | 5.0 | 0.022 | H | -69.3 | -31.8 | 5.0 | 0.022 | 0.0 |
3NP HOH |
5.706 2.663 |
NH2 O |
O1 O |
||
| 2fbw | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2005-12-20 | ARG | A:269 | A:269 | 6.0 | 0.027 | H | -72.6 | -34.6 | 6.0 | 0.027 | 0.0 |
Y3P UNL UNL HOH |
5.739 4.819 9.422 2.927 |
NH2 O NH1 O |
O1 C2 OAA O |
||
| ARG | E:269 | N:269 | 6.0 | 0.027 | H | -72.2 | -34.1 | NA | NA | NA | |||||||||||||
| 2h88 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ARG | A:269 | A:269 | 6.0 | 0.027 | H | -71.4 | -33.1 | 6.0 | 0.027 | 0.0 |
TEO HOH |
5.569 2.690 |
NH2 O |
O1B O |
||
| ARG | E:269 | N:269 | 5.0 | 0.022 | H | -73.1 | -34.1 | NA | NA | NA | |||||||||||||
| 2h89 | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2006-06-20 | ARG | A:269 | A:269 | 11.0 | 0.049 | H | -63.7 | -31.0 | 11.0 | 0.049 | 0.0 |
MLI HOH |
5.162 2.952 |
NH2 NH1 |
O6 O |
||
| 2wqy | 1 | Q9YHT1 | 91.79 | 0.0 |
X-RAY |
2010-08-25 | ARG | A:269 | A:269 | 5.0 | 0.022 | H | -70.9 | -33.9 | 5.0 | 0.022 | 0.0 |
UNL OAA HOH |
6.676 5.778 2.835 |
O NH2 NH1 |
O6 O4 O |
||
| ARG | E:269 | N:269 | 5.0 | 0.022 | H | -70.3 | -34.3 | NA | NA | NA | |||||||||||||
| 6myo | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:269 | A:269 | 7.0 | 0.031 | H | -73.0 | -34.1 | 7.0 | 0.031 | 0.0 |
OAA HOH |
5.629 2.635 |
NH2 NH1 |
O5 O |
||
| 6myp | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:269 | A:269 | 7.0 | 0.031 | H | -71.3 | -22.8 | 7.0 | 0.031 | 0.0 |
OAA HOH |
5.987 2.303 |
NH2 O |
O5 O |
||
| 6myq | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:269 | A:269 | 8.0 | 0.036 | H | -71.3 | -32.8 | 8.0 | 0.036 | 0.0 |
Y3P HOH |
5.574 2.799 |
NH2 NE |
O1 O |
||
| 6myr | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-10-16 | ARG | A:269 | A:269 | 7.0 | 0.031 | H | -74.6 | -30.9 | 7.0 | 0.031 | 0.0 |
OAA |
5.565 |
NH2 |
O5 |
||
| 6mys | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:269 | A:269 | 7.0 | 0.031 | H | -71.9 | -31.1 | 7.0 | 0.031 | 0.0 |
OAA |
5.389 |
NH2 |
O5 |
||
| 6myt | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:269 | A:269 | 6.0 | 0.027 | H | -74.4 | -24.0 | 6.0 | 0.027 | 0.0 |
OAA UNL UNL UNL HOH |
5.499 9.535 6.144 4.917 2.410 |
NH2 NH2 O O O |
O5 O O O O |
||
| 6myu | 1 | F1NPJ4 | 91.79 | 0.0 |
X-RAY |
2019-11-06 | ARG | A:269 | A:269 | 7.0 | 0.031 | H | -75.7 | -29.7 | 7.0 | 0.031 | 0.0 |
OAA UNL HOH |
5.593 4.864 2.708 |
NH2 O NH1 |
O5 O O |
||
AlphaFold DB
| Entity | Residue | Monomer | View | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ID | Entity | Uniprot | Identity | Evalue | Name | Label | Auth | ASA | rASA | SS | φ | ψ | |
| af-p31040-f1 | 1 | P31040 | 100.0 | 0.0 | ARG | A:312 | A:312 | 6.0 | 0.027 | H | -71.2 | -35.6 | |